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Summary Expression Gene Literature (5) GO Terms (8) Nucleotides (69) Proteins (36) Interactants (219) Wiki
XB-GENEPAGE-488766
Gene Symbol: hdac4

Gene Name: histone deacetylase 4

Synonyms: ( Add synonyms , Nomenclature history )

Gene Function: regulation of gene expression

Protein Function :
Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an importan...[+]

Interactants: Loading ...
Diseases:  OMIM: CHROMOSOME 2q37 DELETION SYNDROME

External Disease Links: ClinVar, MalaCards, KEGG Disease, DECIPHER
 
Xenbase Gene ID XB-GENE-488767 XB-GENE-17335610 XB-GENE-6486313
Gene Symbol hdac4 hdac4.L hdac4.S
Chromosome Chr09 chr9_10L chr9_10S
Molecules tropicalis laevis.L laevis.S
Genomic Sequence Version 9.1 Version 9.2 Version 9.2
CDS Gene model Gene model Gene model
Entrez Gene 100489340
108701411
108703026
mRNA NCBI Nucleotide NCBI Nucleotide NCBI Nucleotide
Protein NCBI Protein TrEMBL NCBI Protein NCBI Protein TrEMBL
Genomic tropicalis laevis.L laevis.S
Genome Browser
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics tropicalis laevis.L laevis.S
Embryonic Protein Expression Stage profile:
Data Mining tropicalis laevis.L laevis.S
XenMine hdac4 hdac4.L hdac4.S
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM:Gene, HGNC, GeneCards HDAC4 OMIM Ensembl, Protein Atlas, Allen Brain Atlas
mouse
MGI, AGR Hdac4 MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
zebrafish
ZFIN, AGR hdac4 ZFIN Ensembl
chicken
GEISHA HDAC4 Ensembl
fruit fly
FLYBASE HDAC4 Ensembl
worm
WORMBASE
Publications
First A DNAJB chaperone subfamily with HDAC-dependent activities suppresses toxic protein aggregation., Mol Cell 2010                
Most Recent BAP1 regulates epigenetic switch from pluripotency to differentiation in developmental lineages giving rise to BAP1-mutant cancers., Sci Adv 2019  
All View All Papers 1 paper(s) referencing OMIMs
Functional Ontologies tropicalis laevis.L laevis.S
GO 8 terms 0 term 5 terms
PANTHER hdac4
KEGG Pathways K11406
KOG [B] Histone deacetylase complex, catalytic component HDA1
Reagents tropicalis laevis.L laevis.S
CRISPRscan Tracks hdac4
Clones Horizon Horizon Horizon Source BioScience

Symbol legend: - Blast this sequence    - View this sequence       - Literature or expression images  
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