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Summary Expression Gene Literature (8) GO Terms (7) Nucleotides (192) Proteins (45) Interactants (31) Wiki
XB-GENEPAGE-489111
Gene Symbol:
fnbp1l

Gene Name:
formin binding protein 1 like

Synonyms:
toca-1 , toca1 ( Add synonyms , Nomenclature history )

Gene Function:
mediator of Cdc42-dependent actin nucleation

Protein Function :
Required to coordinate membrane tubulation with reorganization of the actin cytoskeleton during endocytosis. Essential for autophagy of intracellular bacterial pathogens. Promotes cdc42-induced actin p...[+]



Interactants:
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Diseases: 


External Links:
 
Xenbase Gene ID XB-GENE-489112 XB-GENE-865835 XB-GENE-17338248
Gene Symbol fnbp1l fnbp1l.L fnbp1l.S
Chromosome Chr04 chr4L chr4S
Molecules tropicalis laevis.L laevis.S
Genomic Sequence Version 9.1 Version 9.2 Version 9.2
CDS Gene model Gene model Gene model
Entrez Gene 448740
735241
446802
mRNA RefSeq RefSeq RefSeq
Protein RefSeq Swiss-Prot RefSeq RefSeq
Genomic
tropicalis laevis.L laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics tropicalis laevis.L laevis.S
Embryonic Protein Expression Stage profile: Stage profile:
Data Mining tropicalis laevis.L laevis.S
XenMine fnbp1l fnbp1l.L fnbp1l.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards FNBP1L OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Fnbp1l MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Fnbp1l Ensembl
zebrafish
ZFIN, AGR fnbp1l ZFIN Ensembl
chicken
GEISHA FNBP1L Ensembl
fruit fly
worm
Publications
First Toca-1 mediates Cdc42-dependent actin nucleation by activating the N-WASP-WIP complex., Cell 2004  
Most Recent Chromatin Accessibility Impacts Transcriptional Reprogramming in Oocytes., Cell Rep 2018  
All View All Papers
Functional Ontologies tropicalis laevis.L laevis.S
GO 7 terms 1 terms 7 terms
PANTHER fnbp1l
KEGG Pathways K20121 K20121 K20121
KOG [Z] Cdc42-interacting protein CIP4
Reagents tropicalis laevis.L laevis.S
CRISPRscan Tracks fnbp1l
Antibodies Fnbp1l Ab1 Fnbp1l Ab1
ORFs fnbp1l.L ORF1
Clones Horizon Source BioScience Horizon Source BioScience Horizon

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info   [+] Expand list
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