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Summary Expression Gene Literature (8) GO Terms (14) Nucleotides (156) Proteins (38) Interactants (151) Wiki
XB-GENEPAGE-489121
Gene Symbol:
actn2

Gene Name:
actinin alpha 2

Synonyms:
( Add synonyms , Nomenclature history )

Gene Function:
actin bundling

Protein Function :


InterPro :
EF hand dom , Spectrin/alpha-actinin , CH-domain , Actinin actin-bd CS [+]

Interactants:
Loading ...

Diseases: 


Disease Ontology:
dilated cardiomyopathy 1AA

OMIM:
CARDIOMYOPATHY, DILATED, 1AA, WITH OR WITHOUT LEFT VENTRICULAR NONCOMPACTION; CM

External Links:
 
Xenbase Gene ID XB-GENE-489122 XB-GENE-17345825 XB-GENE-865836
Gene Symbol actn2 actn2.L actn2.S
Chromosome Chr5 chr5L chr5S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.1 Version 9.1
CDS Gene model Gene model Gene model
Entrez Gene 448602
446752
432169
mRNA RefSeq NCBI Nucleotide NCBI Nucleotide
Protein NCBI Protein RefSeq  More.. NCBI Protein RefSeq  More.. NCBI Protein RefSeq  More..
Genomic
 X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics X. tropicalis X. laevis.L X. laevis.S
Embryonic Protein Expression Stage profile: Stage profile:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine actn2 actn2.L actn2.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC, AGR, Monarch, OMIM, GeneCards ACTN2 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Actn2 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Actn2 Ensembl
zebrafish
ZFIN, AGR ZFIN, AGR actn2b actn2a ZFIN Ensembl
chicken
GEISHA ACTN2 Ensembl
fruit fly
Publications
First Distinct roles for telethonin N-versus C-terminus in sarcomere assembly and maintenance., Dev Dyn 2010                    
Most Recent Regulation of actin assembly by PI(4,5)P2 and other inositol phospholipids: An update on possible mechanisms., Biochem Biophys Res Commun 2018  
All View All Papers 2 paper(s) referencing morpholinos
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 14 terms 2 terms 2 terms
PANTHER actn2
KEGG Pathways K21073 [+] K21073 K05699 [+]
KOG [Z] Ca2+-binding actin-bundling protein (actinin), alpha chain (EF-Hand protein superfamily)
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks actn2
Antibodies Actn2 Ab1 , Actn2 Ab2 , Actn2 Ab3 Actn2 Ab1 , Actn2 Ab2 , Actn2 Ab3
Clones Horizon Source BioScience Horizon Horizon
Plasmids Addgene Addgene

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