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Summary Expression Gene Literature (238) GO Terms (18) Nucleotides (1446) Proteins (40) Interactants (505) Wiki
XB-GENEPAGE- 489467

Gene Symbol: ran

Gene Name: RAN, member RAS oncogene family

Synonyms: ran-1 , tc4 , gsp1 , ara24 , RanTC4
Add Xenopus synonyms , Nomenclature history

Gene Function: small GTPase

Protein Function :
GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle.


Interactants: Loading ...

Disease Ontology Associations:

OMIM Disease Associations: RAS-RELATED NUCLEAR PROTEIN; RAN
 
Xenbase Gene ID XB-GENE-489468 XB-GENE-17336523 XB-GENE-865870
Gene Symbol ran ran.L ran.S
Chromosome Chr01 chr1L chr1S
Molecules tropicalis laevis.L laevis.S
Gene Genomic sequence Genomic sequence Genomic sequence
CDS Gene model
Entrez Gene
Entrez Gene
Entrez Gene
mRNA Refseq Refseq Refseq
Protein Refseq Swiss-Prot TrEMBL TrEMBL Refseq Swiss-Prot Swiss-Prot TrEMBL Refseq Swiss-Prot TrEMBL
Genomic tropicalis laevis.L laevis.S
Genome Browser
Links
Genomic Synteny Genomicus
Expression tropicalis laevis.L laevis.S
Ensembl Ensembl
UniGene Str.47018 [+] Xl.57143
RNA-Seq profile Stage profile: Stage profile:       Tissue heatmap:
Experimental regulation Regulation heatmap:
Images 5 expression image(s) for tropicalis and laevis
Data Mining tropicalis laevis.L laevis.S
XenMine ran ran.L ran.S
Phenotype tropicalis laevis.L laevis.S
Smith Morpholino Screen    
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM:Gene, HGNC, GeneCards RAN OMIM, MalaCards, KEGG Disease, DECIPHER Ensembl, Protein Atlas, Allen Brain Atlas
mouse
MGI, AGR Ran MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
zebrafish
ZFIN, AGR ran ZFIN Ensembl
chicken
GEISHA RAN Ensembl
fruit fly
FLYBASE Ran Ensembl
worm
WORMBASE
Publications
First: Substrate pathways demonstrated by transplanted Mauthner axons. [J Comp Neurol 1981]
Most recent: The quest for the holy "G" of chromosomal passengers. [Dev Cell 2017]
View All Papers 3 paper(s) referencing morpholinos 2 paper(s) referencing OMIMs 2 paper(s) referencing Disease Ontologies
Functional Ontologies tropicalis laevis.L laevis.S
GO 18 terms 7 terms 7 terms
PANTHER ran
KEGG Pathways K07936 K07936 K07936
KOG [U] GTPase Ran/TC4/GSP1 (nuclear protein transport pathway), small G protein superfamily
Reagents tropicalis laevis.L laevis.S
CRISPR / TALEN CRISPR tools CRISPR tools CRISPR tools
Clones
GE Dharmacon GE Dharmacon GE Dharmacon
Source BioScience Source BioScience
Morpholino ran MO1 , ran MO2 ran MO1 , ran MO2 ran MO1 , ran MO2
ORF ran-1-prov ORF1
Affymetrix 1.0 Str.6581.1.S1_at [+] Xl.4635.1.S1_at
Affymetrix 2.0 Xl2.4635.1.S1_a_at [+]

Symbol legend[+]
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Major funding for Xenbase is provided by the National Institute of Child Health and Human Development, grant P41 HD064556