Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Summary Expression Gene Literature (3) GO Terms (13) Nucleotides (164) Proteins (33) Interactants (33) Wiki
XB-GENEPAGE- 489577

Gene Symbol: pacsin2

Gene Name: protein kinase C and casein kinase substrate in neurons 2

Synonyms: x-PACSIN2 , sdpii
Add Xenopus synonyms , Nomenclature history


Gene Function: protein-tyrosine kinase

Protein Function:
Lipid-binding protein that is able to promote the tubulation of the phosphatidic acid-containing membranes it preferentially binds. Plays a role in intracellular vesicle-mediated transport. Involved in...[+]


Interactants: YYY

OMIM Disease Associations:
1/2
 
Xenbase Gene ID XB-GENE-489578 XB-GENE-17330265 XB-GENE-489582
Gene Symbol pacsin2 pacsin2.L pacsin2.S
Chromosome scaffold_259 chr3L chr3S
Molecules tropicalis laevis.L laevis.S
Gene GBrowse 8.0 JBrowse 8.0 GBrowse 4.1 JGI Genome 4.1 Ensembl 4.1 GBrowse 9.1 JBrowse 9.1 GBrowse 9.1 JBrowse 9.1 GBrowse 7.2 JBrowse 7.2 GBrowse 6.0
Entrez Gene
Entrez Gene
Entrez Gene
mRNA Refseq NCBI Nucleotide Refseq
Protein Refseq TrEMBL NCBI Protein Refseq Swiss-Prot
Genomic tropicalis laevis.L laevis.S
Genome Browser
GBrowse
tropicalis genome v8.0 gene model
GBrowse
laevis genome v9.1 gene model
GBrowse
laevis genome v9.1 gene model
Links
Genomic Synteny Genomicus   Metazome
Expression tropicalis laevis.L laevis.S
Ensembl Ensembl
UniGene Str.27565 Xl.52492 [+]
RNA-Seq profile Stage profile: Stage profile:       Tissue heatmap:
Images 6 expression image(s) for tropicalis and laevis
Data Mining tropicalis laevis.L laevis.S
XenMine pacsin2 pacsin2.L pacsin2.S
Phenotype tropicalis laevis.L laevis.S
Smith Morpholino Screen    
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM:Gene, HGNC, GeneCards PACSIN2 OMIM, MalaCards, KEGG Disease, DECIPHER Ensembl, Protein Atlas, Allen Brain Atlas
mouse
MGI Pacsin2 MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
zebrafish
ZFIN pacsin2 ZFIN Ensembl
chicken
GEISHA PACSIN2 Ensembl
fruit fly
worm
WORMBASE
Publications
First: PACSIN2 is a regulator of the metalloprotease/disintegrin ADAM13. [Dev Biol 2000]
Most recent: PACSIN2 regulates cell adhesion during gastrulation in Xenopus laevis. [Dev Biol 2008]
View All Papers
Functional Ontologies tropicalis laevis.L laevis.S
GO 4 terms 0 term 12 terms
EC now EC:2.7.10.1 and EC:2.7.10.2
PANTHER pacsin2
KEGG Pathways K20123 K20123
KOG [TUZ] Adaptor protein PACSIN
Reagents tropicalis laevis.L laevis.S
CRISPR / TALEN CRISPR tools CRISPR tools CRISPR tools
Clones
GE Dharmacon GE Dharmacon GE Dharmacon
Source BioScience Source BioScience
Antibody Pacsin2 Ab1 Pacsin2 Ab1
Morpholino pacsin2 MO1 , pacsin2 MO2 pacsin2 MO1 , pacsin2 MO2 pacsin2 MO1 , pacsin2 MO2
ORF slc2a14 ORF2
Affymetrix 1.0 Str.27565.1.S1_at Xl.17287.1.A1_at [+]
Affymetrix 2.0 Xl2.6995.1.S1_at Xl2.551.1.S1_at [+]

Symbol legend[+]

My Xenbase: [ Log-in / Register ]
version: [4.5.0]

Major funding for Xenbase is provided by the National Institute of Child Health and Human Development, grant P41 HD064556