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Summary Expression Gene Literature (57) GO Terms (4) Nucleotides (563) Proteins (43) Interactants (328) Wiki
XB-GENEPAGE-489657
Gene Symbol:
lmnb1

Gene Name:
lamin B1

Synonyms:
Lamin-L(I) , lamin-b , lamin b , lamin b1 ( Add synonyms , Nomenclature history )

Gene Function:
nucleoskeletal protein

Protein Function :
Lamins are components of the nuclear lamina, a fibrous layer on the nucleoplasmic side of the inner nuclear membrane, which is thought to provide a framework for the nuclear envelope and may also inter...[+]



Interactants:
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Diseases: 


Disease Ontology:
adult-onset autosomal dominant demyelinating leukodystrophy

OMIM:
LEUKODYSTROPHY, DEMYELINATING, ADULT-ONSET, AUTOSOMAL DOMINANT; ADLD

External Links:
 
Xenbase Gene ID XB-GENE-489658 XB-GENE-489662 XB-GENE-17340188
Gene Symbol lmnb1 lmnb1.L lmnb1.S
Chromosome Chr1 chr1L chr1S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.1 Version 9.1
CDS Gene model Gene model Gene model
Entrez Gene 394806
379745
397911
mRNA RefSeq NCBI Nucleotide NCBI Nucleotide
Protein NCBI Protein RefSeq  More.. NCBI Protein RefSeq  More.. RefSeq Swiss-Prot  More..
Genomic
X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics X. tropicalis X. laevis.L X. laevis.S
Embryonic Protein Expression Stage profile: Stage profile:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine lmnb1 lmnb1.L lmnb1.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards LMNB1 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Lmnb1 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Lmnb1 Ensembl
zebrafish
ZFIN, AGR lmnb1 ZFIN Ensembl
chicken
GEISHA LMNB1 Ensembl
fruit fly
worm
Publications
First Detection of nuclear lamin B epitopes in oocyte nuclei from mice, sea urchins, and clams using a human autoimmune serum., Dev Biol 1987  
Most Recent Extreme nuclear branching in healthy epidermal cells of the Xenopus tail fin., J Cell Sci 2018  
All View All Papers 4 paper(s) referencing morpholinos 1 paper(s) referencing Disease Ontology
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 4 terms 4 terms 2 terms
PANTHER lmnb1
KEGG Pathways K07611 K07611 K07611
KOG [DY] Nuclear envelope protein lamin, intermediate filament superfamily
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks lmnb1
Antibodies Lmnb1 Ab1 , Lmnb1 Ab2 , Lmnb1 Ab3 , Lmnb1 Ab4 , Lmnb1 Ab5 Lmnb1 Ab2 , Lmnb1 Ab3 , Lmnb1 Ab4 , Lmnb1 Ab5 Lmnb1 Ab1 , Lmnb1 Ab5
ORFs lmnb1 ORF1 lmnb1.L ORF1 lmnb1.S ORF1
Clones Horizon Source BioScience Horizon Source BioScience Horizon
Plasmids Addgene Addgene

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info   [+] Expand list
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