Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Summary Expression Gene Literature (152) GO Terms (9) Nucleotides (924) Proteins (34) Interactants (1505) Wiki
XB-GENEPAGE-489926
Gene Symbol:
tuba4b

Gene Name:
tubulin alpha 4b

Synonyms:
tuba4 , alpha tubulin , alpha-tubulin , tuba4a ( Add synonyms , Nomenclature history )

Gene Function:
microtubule component

Protein Function :
Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.



Interactants:
Loading ...

Diseases: 


External Links:
 
Xenbase Gene ID XB-GENE-489927 XB-GENE-865914 XB-GENE-17341026
Gene Symbol tuba4b tuba4b.L tuba4b.S
Chromosome Chr09 chr9_10L chr9_10S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 9.1 Version 9.2 Version 9.2
CDS Gene model Gene model Gene model
Entrez Gene 549448
493577
108702924
mRNA RefSeq RefSeq NCBI Nucleotide
Protein RefSeq Swiss-Prot  More.. NCBI Protein RefSeq  More.. NCBI Protein NCBI Protein  More..
Genomic
X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics X. tropicalis X. laevis.L X. laevis.S
Embryonic Protein Expression Stage profile:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine tuba4b tuba4b.L tuba4b.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, TUBA4B Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Tuba4a MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
zebrafish
chicken
GEISHA TUBA4AL Ensembl
fruit fly
worm
Publications
First Monoclonal antibodies specific for an acetylated form of alpha-tubulin recognize the antigen in cilia and flagella from a variety of organisms., J Cell Biol 1985  
Most Recent The neurodevelopmental disorder risk gene DYRK1A is required for ciliogenesis and control of brain size in Xenopus embryos., Development 2020                              
All View All Papers 33 paper(s) referencing morpholinos 8 paper(s) referencing OMIMs 20 paper(s) referencing Disease Ontology
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 9 terms 6 terms 6 terms
PANTHER tuba4b
KEGG Pathways K07374 K07374
KOG [Z] Alpha tubulin
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks tuba4b
Antibodies Tuba4b Ab11 , Tuba4b Ab12 , Tuba4b Ab13 , tuba4a Ab20 , Tuba4b Ab1 , Tuba4b Ab3 , Tuba4b Ab4 , Tuba4b Ab5 , Tuba4b Ab6 , Tuba4b Ab7 , Tuba4b Ab8 , Tuba4b Ab9 , Tuba4b Ab10 , Tuba4b Ab14 , Tuba4b Ab15 , Tuba4b Ab17 , Tuba4b Ab18 , Tuba4b Ab19 , Tuba4a Ab3 Tuba4b Ab11 , tuba4a Ab20 , Tuba4b Ab1 , Tuba4b Ab3 , Tuba4b Ab4 , Tuba4b Ab5 , Tuba4b Ab6 , Tuba4b Ab7 , Tuba4b Ab8 , Tuba4b Ab9 , Tuba4b Ab10 , Tuba4b Ab12 , Tuba4b Ab13 , Tuba4b Ab14 , Tuba4b Ab15 , Tuba4b Ab17 , Tuba4b Ab18 , Tuba4b Ab19 , Tuba4a Ab3 tuba4a Ab20 , Tuba4b Ab5 , Tuba4b Ab4 , Tuba4b Ab14 , Tuba4b Ab19 , Tuba4b Ab3 , Tuba4b Ab7 , Tuba4b Ab8 , Tuba4b Ab9 , Tuba4b Ab1 , Tuba4b Ab10 , Tuba4a Ab3 , Tuba4b Ab17
ORFs tuba4b.L ORF1
Clones Horizon Source BioScience Horizon Source BioScience Horizon
Plasmids Addgene Addgene

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info   [+] Expand list
Xenbase: The Xenopus Model Organism Knowledgebase.
Version: 4.15.0
Major funding for Xenbase is provided by grant P41 HD064556