Gene Symbol: rangap1 Gene Name: Ran GTPase activating protein 1 Synonyms: fug1, rna1p Add Xenopus synonyms Gene Function: GTPase activator Interactants: ran(12) , rcc1(7) , ranbp2(6) , ranbp1(4) , sumo1(4) , cdkn2c(3) , ube2i(3) View All

Molecules		tropicalis	laevis a		laevis b
Gene		JGI XT Genome 7.1 JGI XT Genome 4.1 Ensembl 4.1	JGI XL Genome 6.0
		Entrez Gene	Entrez Gene		Entrez Gene
mRNA		Refseq >NM_001123468|Xenopus (Silurana) tropicalis Ran GTPase activating protein 1 (rangap1), mRNA GGCGACTGGGAAGCTGTACTTGCGGACTAGAGAAAAAGTGTGACAATGGCTTCTGAAGATATTGCGCAGTTGACAGATTCCCTGGCAAAGACAAAGGTGGAGGGAGGAGGAGAGCTAAGCTTTAAAGGGAAAAGCCTGAAACTCAACACTGCCCAGGATGCTGAAGAAGTGATTCGGGAAATTGAAGATTTTGAAGGGCTGCATGCTCTGCGGCTGGAAGGCAACACTGTGGGACTGGAGGCAGCTAAAGCAATAGCCAAAGTTCTGGAAAAGAAACCTGATCTGAAGCGCTGCCACTGGAGTGATATGTTTACAGGAAGGTTAAGGTCCGAAATTCCACCTTCTTTGATATCTCTTGGTGATGCTTTGATTACAGCTGGAGCTCAGCTGACCGAGCTGGATTTAAGTGACAATGCTTTTGGTCCTGATGGAGTGCGTGGTTTTGAAGCTCTTCTTAAGAGTCCAGCTTGTTTCACTCTACAGGAGCTCAAACTGAACAACTGTGGAATGGGAATTGGTGGAGGAAAGATCCTGGCTGCAGCCCTAACTGAGTGTTACAAGAAGTCTAGTTCCCATGGTAAGCCTCTGGCACTGAAAGTATTCATAGCAGGAAGGAACCGCTTGGAGAATGATGGTGCCACTGCACTGGCTGAAGCTTTTCGTCTCATTGGCACCTTAGAGGAGGTACACATGCCGCAGAATGGCATTAATCATGCTGGCATCACTGCTTTGGCAGAATCTTTTAAAGCCAACTCTTTGCTGAAAGTGATCAACCTTAATGATAATACATTCACAGAAAAGGGTGGCATTGCTATGGCTGAGGCATTAAAGACACTCAGGCAAGTGGAAGTAATCAATTTTGGGGACTGTTTGGTCCGTTCCAAGGGAGCACAGGCTATAGCAACTGCATTAAAAGAAGGGCTTCATAAATTAAAGGAGCTTAACCTCTCTTTTTGTGAAATTAAACGAGATGCAGCAGTGGTCTTAGCAGAATCTGTGGAAGATAGGTCTGAATTACAGAAACTGGATTTAAATGGAAATTGTCTTGGTGAGGGGGGCTGTGAGCAGGTGCAGGAAATCCTGGAAGGCATTAGCATGGCTAACATATTAGGCTCTTTAAGTGATGATGAGGGGGATGAAGATGAGGATGAAGATGAAGTAGATGATGATGACGACGATGATGACGACGACGATGATGAAGATGATGAAGAGGACGTGGAGGAGGAGGAAGAGGAGGAAGATGTAGATGATAATGAAAACAGAACAAAGCCTAATAAAATTTCATCACATGTATCCACACCAGCCGCTCCACCTAAACTTCCAGTTGATGCATCCACCTTTCTTAGCTTTCCCTCTCCTGAGAAGCTTGTGCGCATGGGTCCTAAACGTTCTACAATGATAATGCAGCAGATCGATGTTGCAGATACGGAAAAGGTGGTCCAAACGTTCATCCAGGTCTCCTCTGTGTACAGGGATGACAGTGAAGTAAAGGCGGCTGTTGAAGAAACTATTGATGGTCTAATGAAGAAGGCTTTTGAAAGCCGAGGTTTCCAAGAAAATCTGTTTATCACTAGTCTATTGGTGCATATGGGACTTCTCAAGAGTGAAGACAAAATTAAAACGGTACAGCACTTAAATGGCCCCTTGCTAACTCTGAATCACATGGTACAACAGAATTACTTCCCAAAATCTCTTGTTCCTATACTTCTGGCTTTCATCTCAAAGCCCAACCGTGTCCTGGAAAATAACGCCAGTGCCAGACACACATTGCTGCACAACCTTCATAATCTGTAACCTGCTTTGCTTCAACTTGGACTAAACTTTACCCAGCCCACAAAACATAAAAGCTCTTCATAGCAGGTTATATATGAGCAAGGGTTTATTAGGCATATTGCTGGGGAATAAGTTCCTTCTGGTCTTACCTACAAGGGGCCCCATTCCAGTCTTTTTGTTTACATTTGAAAAGAACTGTTCACCTCTCAATACCTTGATGATCCAGAGGCCCAGATTTGGACTCCAGATGAGCATTTTTTATAGGTTCATTGAGTGTTGTGTAACTGAATAATGTTACATCATTGGACAGTTCTCATATTCTCATTGAGTGGCGCATCTGTGTTTAATGCCAAATTATTGGATAATACTTTGTAAATTGAGTTTAGGGACAGTAAAAGTACTGTATCTTTATCATAAGCGATTGTACATGTATACACTGTATTCCTTCCTTAACGAGAGAAGCTGTAATGCATATCGGGTGCATATTTAGCCCTTGTAATTCCTGAAACAGTCTACTCCTGTTCCTGCCATAACTTTAGCCTGTTTGTCTGGCAGAGCTTGGCTTTAAGCTAAGGGAACTATCATGCATAGTACTCAAAGGGTAACAGATTACTCTTACATTTGTATACACTGCAAATCATATTCATGTTTTATTTAAATTACCTGGAGCAGATACTTGTGTTTTGGAAATACTTGTGCAGTTATTACTTGGCACAATAGAATTGCATTCAGTGATTTAATTACGCTCACTCCTTAGTCTGCAATTGTTCTACAGGAAGAATGTACCATAGGCCTTGCAGATGCCATTCATACCTAATGTGCCAGTACCCTGATGGCTGTAAGGTATTGCTGCTGTTCCTGTATAGTTTTCTATGTAGTCCTCTTTGGTGCCTACTCAATGGACATTTGAAATTGTTTTAGTCTTTATAGCTTTTAGAGTAGATTTGGGAGCAATTGTGCAAAAGGAAAAAAAAAATATGTAGCATTAATGTCCTTTAATGGCTGAGTAGAAAAAGAGTGTAAGCCTTTGGGTATCTGTCATCAAACAGCATCCTACCGTGCTTCCGCCAGCTGATTGCATCTACACGTGGGGGCGGCTTGCTCTGCTTTTTATAATCAGTTATTAAAGATTTCCTCTCTATACCAACACTGCTGGCAAGAGTGTTGGAGTTTTTTTTTTTTTTTGTTTTTTTTTAAGACGCAAAATGTCCCCAGTGATTTCCTTTGTAAATAATTTGTATTGCTTCTCAAGCAAAGACCCTACAGCTTCAGGGCGACTGTTGCTTCACTTCCAGGAGCCATCATGGATATCTATAAGGCCTATTCCAGAATGGATATTCACATCATATCATGGCTCTCCTTGATAAAACGATTTAGCTTGGGTGTGTGTATAGACTTGCTCACTTACCTCAAACACCACTTAAAAAAAAAAAAAAA	Refseq >NM_001086761|Xenopus laevis Ran GTPase activating protein 1 (rangap1-a), mRNA CAAGGCAAAAAAAGAAGAAAAAAAAACTCTCTCGCTTTAAGCCGCGTGCAGGGTGACGATTCCAAGCCGGGCAGCTTCTGGAAATCAAGTGAGAAAAAGCATAAAGATGGCTGCTGAAGATATCGCACAGTTGGCAGATTGCTTGGCAAAGGCAAAGGTTGGAGAAGGAGAGCTGAGCTTTAAAGGGAAAACACTAAAACTAAACACTGCCCAAGATGCTGAAGAAGTAATTCGGGAAATTGAAGAATTTGAAGGGCTGCAGGCTCTGCGTCTGGAAGGAAATACTGTGGGAGTGGAGGCAGCTAAAGTAATAGCCAAAGCTCTGGAAAAGAAATCTGATCTAAAGCGCTGCCACTGGAGTGATATGTTCACAGGGAGGTTGAGGTCCGAAATTCCACCAGCTTTGATATCTCTTGGGGATGCTTTGATTACAGCTGGAGCTCAACTGACAGAGCTGGACTTAAGTGACAATGCATTTGGTCCTGATGGAGTGCGTGGTTTTGAAGCTCTGCTCAAAAGTCCAACTTGTTTTACTCTACAGGAGCTTAAACTAAACAACTGTGGAATGGGAATTGGTGGAGGCAAGATCCTGGCTGCAGCCCTAACTGAGTGCTACAAGAAGTCTAGTTCCCATGGTAAGCCTCTGGCACTGAAAGTGTTCATAGCAGGAAGGAACCGCTTGGAAAATGATGGTGCCACCGCACTGTCCGAGGCTTTTCGGCTCATCGGCTCCTTGGAGGAGGTACACATGCCCCAGAATGGCATTAACCATGCTGGCATCACTGCTTTGGCAGACTCATTTAAAGCCAACTCTTTGCTGAAAGTGATCAACCTTAATGATAATACATTCACAGAGAAGGGTGGCATCGCTATGGCTGAGGCGTTAAAGACACTCAGGCAAGTGGAAGTAATCAATTTTGGGGACTGTTTGGTCCGCTCAAAGGGAGCACAGGCTATAGCATCAGCACTAAAAGAAGGGCTTCATAAATTAAAGGAGCTTAACCTTTCCTTTTGTGAAATTAAACGAGATGCAGCTGTGAGCTTAGCAGAATCTGTGGAAGATAAGTCTGACTTAGAGAAATTGGATTTAAATGGAAATTGTCTTGGTGAGGGGGGGTGTGAGCAGGTGCAGGAAATCTTGGATGGCATTAACATGGCTAACATACTAGGTTCTTTAAGTGATGATGAGGGTGATGAAGATGAAGACGAAGTGGATGATGATGACGACGACGATGATGATGAAGATGATGATGACGATGATGATGATGATGAAGAGGAAGTCGAGGAAGAAGAAGAAGAGGTGGAAGGAGGAGATGATGACGATAATGAAGAGAAGTCCAAAAAAATTCTATCACATGCATCAACACCCGCTTCTCCACCTAAACTTCCTGTTGATGTATCCACCTTTCTTAGCTTTCCTTCTCCAGATAAACTTGTTCGCATGGGTCCTAAACGTTCTACAATGATCGCACAGCAGGTCAATGTTTCAGATACAGAAAAGGTTGTTCAAGCTTTCATCCAGGTCTCGTCAGTGTACAGGGATGAGGGTGAAATAAAGGCGGCTGTTGAAGAAACTATTGATGGTTTAATGAAGGAGGCTTTTCAAAACACAGGTTTTCAAGCATGTCTATTTATCACTAATCTACTAGTGCATATGGGACTTCTTAAGAGTGAAGACAAAATTAAAACAATAACGCACTTAAATGGCCCCTTGCTAACTCTGAATCACATGGTACAGCAGAATTACTTCCCCAAGTCTCTTGTTCCTATACTTCTGGCTTTCATCTCAAAGCCCAACCGTGTCCTGGAAAATAACGCCAGTGCCCGACACACGTTGCTGCACAACCTTCATAATCTGTAACCTGTTTTGCTTCAACTGGACTAAACGACCCAGCCCACGAAATGTAAAAGCTCTCCAAAGCCCTGTTATATAAAAGCAAGGATTTATTAGGATTTATTTATTGCTGGTGAATAAGTTCCTTCTAGTCTTACCCATGGGGGCCCCATTCCAGTCTTTTTGTTTACATATGAAAAGAACCGTTCACCTCTCCGTACCTTGAGGACCCCGAGGCCCAGATTTACACTCCAATGGGGAATTTTTATAGGTCCATCGAGCGTTGCCTCATTGAATAATTTTACATCTTTGGACAGTAGTTTCACGGAGTCTCTGTTTGATGCCATGTTATTGGATAATACTTTGTAAATTATTTTAGGGACAGTAAAAGTACTGTACGCTATTTCCTCTTTATCATAAGCGATTGTGTATACACTGTATTCTTTCCTTGAACAAGTGAAGCTATTATGCATATCAGGTGCAGTTGCATATATAGCCCTTGTAGTATCCGTAAAAAAAAAAAAAAA		Refseq >NM_001172197|Xenopus laevis Ran GTPase activating protein 1 (rangap1-b), mRNA CTTCAAGCCGGGCAGCTTGTGGAACTCAAGTGAGGAAAAGCGTGAAGATGGCTGCTGAAGATATCGCACAGTTGGCAGATTGCTTGGCAAAGGCAAACGTTGGAGACGGAGAGCTGAGCTTTAAAGGGAAAACTCTGAAACTCAACACTGCCCAAGATGCCGAAGAAGTGATTCGGGAAATTGAAGAATATGAAGGGCTGCAGGCTCTGCGTCTGGAAGGCAATACTGTGGGAGTGGAGGCAGCTAAAGCAATAGCCGAAGTTCTGCAAAGGAAACCTGATCTGAAGCGTTGCCACTGGAGTGATATGTTTACAGGGAGGTTAAGGCCCGAGATTCCAACTGCTTTGAGATCTCTTGGTGATGCTTTGATTACAGCTGGAGCTCAATTGACTGAACTGGACTTAAGTGACAATGCATTTGGACCTGATGGAGTGCGTGGATTTGAAGCTCTTCTCAAAAGTCCAACTTGTTTTACTCTACAGGAGCTCAAACTGAACAACTGTGGAATGGGAATTGGGGGAGGAAAGATCCTGGCTGCAGCACTAACAGAGTGCCACAAGAAGTCTAGCGCCCATGGTAAGCCTCTGGCATTGAAAGTGTTCATAGCAGGAAGGAACCGCTTGGAAAATGATGGTGCCACTGCACTCTCTGAGGCTTTTCGGCTCATCGGCACCTTGGAGGAAGTACACATGCCTCAAAATGGCATTAATCACGCTGGCATCACCGCTTTGGCAGAATCTTTTAAAGCCAACTCTTTGCTGAAAGTGATTAACCTTAATGATAATACTTTCACAGAAAAGGGTGGCGTCGCTATGGCTGAGGCATTAAAGACACTCAGGCAAGTGGAAGTAATCAATTTTGGGGACTGTTTGGTCCGCTCAAAGGGAGCACAGGCTATAGCGTCTGCACTTAAAGAAGGGCTTCATAAATTAAAGGATCTTAACCTTTCCTATTGTGAAATTAAAGCAGATGCAGCCGTGAGTTTAGTAGAATCGGTGGAAGATAAGTCTGACTTAGAGAAATTGGATTTAAATGGAAATTGTCTTGGTGAGGAGGGCTGTGAGCAGGTGCAGGAAATCCTAGAGAGCATTAACATGGCCAACATATTAGGCTCTTTAAGTGATGATGAGGGTGATGAGGATGAGGATGACGATGATGATGATGATGATGATGATGATGAAGATGAAGATGATGATGAAAATGATGATGAGGAAGTTGAGGAGGAGGAAGAAGAAGTAGAGGAGGAGGAAGGAGGAGATAATGAAAACAAAGAGAAGTCCAAAGAAATTCCATGCTTAAGTGGATCAGCACCAGCTTCTCCACCTAAACTTCCTGTTGATGCATCCACCTTTCTTAGCTTTCCTTCCCCAGAGAAACTTGTGCGCATGGGTCCTAGACGTTCTGCAATGATAGCACAACAGGTCAATGTTGCAGATACAGAAAAGGTGGTCCAAGCTTTCATTCAGGTCTCCTCTGTGTATAGGGAGGATGGTGAAATAAAGGCGGCTGTTGAAGAAACTATTGATGGTTTAATGAAGGAGGCTTTTGAAAACAGAGGTTTCCAAGCAAATGTGTTTATCACTAGTCTACTGGTGCAAATGGGACTTCTTAAGAGTGAAGACAAAATGAAAACAATACCACACTTAAATGGCCCTTTGCTAACTCTGAATCACATGGTACAGCAGAATTACTTCCCAAAGTCTCTTGCTTCTACTCTTCTTGCTTTCATCTCCAAGCCCAACGGTGTCCTGGAAAATAACGCCAGTGCCAGACACACATTGCTGTGCAACCTTCATAATCTGTAACCTGCTTTGCTTCAACTGGACTAAACTTTACCCAGACCACAAAATGTAAAAGCTCTTCGAATCACGTTCTGTAAAATCAAGGATTTTTTAGGCCAAATAGATGGTGAATCAGTTCCTTCTAGTCTTACCTACAGGGGCCCCCATTCCAGTCTTTCTGTTTACATTTGAAAAGAACTGTTCACCTCTCAGTACCTTGAGGATCCAGAGGCCAAGATTGGACTCCAATGAGGACATTTTGATAGGTTCATCGAGTAATATCATTGGACAGTTCTCATAGTTACATTGAGTGGCACGCCTGTGTTTGATGCCACTTTGTAAATTATTTTAGGGACAGTAAAAGTACTGTATGCTACTTCATCTTTATCATAAGCCATTGAATGTGTATACACTGTATTCTTTCCTGGAACCGTGAAGCTATTCTGGAAATCTGGTGCAGTTACATATTTAGCCCTTGTAAATTCAGAAAATCTACTTCTGTTCCTGCTCTATGCTTTGGCCTGTCTGTCTGGAAGGGTTAAAGCTTAAGGAAAGCTCAAGGATAGTGATCAAAGGGTAACCGGTTACTCTTATTTACATTTGTCTACACTGCAAATCATATTCATGTTTTATTTAACTTGTAGCTTTGTTCTGAAATGCCTGTGCAGTTATTAGTTGACACAGTAGAATTGCAATGATGCTCAGTCCTTCTTATTCTGTAATTGTTCTACAGGAAGGATGTACCGTGGGCCTTACAGATACATAATATGATGATACCTGATGGCTGGAAGGTATTGCTGCTGTTCCTGTATAGTTTTGTATTGAGGGCTGAATCCTCTTCGGTGCCTACTTTTTTATAGACATTTGACTTTGAATTAGTCATCTAAAAATTTTTTTACATCTATTGGAGTAGAGTTGAAAGTAACTTTGCAAAAGCAAAACGCATCCAGCAATGCTTCTGCCTACTCACTGAAATTGCAGGCAGAAGTGTTTGAGACTTTTCTTATAAACGTTAAAAAAAATTGGTGGACTTTGTCAGTAACTGTACCGTTATAAATCAAAAAAAAAAAAAAA
Protein		Refseq >NP_001116940|Ran GTPase activating protein 1 [Xenopus (Silurana) tropicalis] MASEDIAQLTDSLAKTKVEGGGELSFKGKSLKLNTAQDAEEVIREIEDFEGLHALRLEGNTVGLEAAKAIAKVLEKKPDLKRCHWSDMFTGRLRSEIPPSLISLGDALITAGAQLTELDLSDNAFGPDGVRGFEALLKSPACFTLQELKLNNCGMGIGGGKILAAALTECYKKSSSHGKPLALKVFIAGRNRLENDGATALAEAFRLIGTLEEVHMPQNGINHAGITALAESFKANSLLKVINLNDNTFTEKGGIAMAEALKTLRQVEVINFGDCLVRSKGAQAIATALKEGLHKLKELNLSFCEIKRDAAVVLAESVEDRSELQKLDLNGNCLGEGGCEQVQEILEGISMANILGSLSDDEGDEDEDEDEVDDDDDDDDDDDDEDDEEDVEEEEEEEDVDDNENRTKPNKISSHVSTPAAPPKLPVDASTFLSFPSPEKLVRMGPKRSTMIMQQIDVADTEKVVQTFIQVSSVYRDDSEVKAAVEETIDGLMKKAFESRGFQENLFITSLLVHMGLLKSEDKIKTVQHLNGPLLTLNHMVQQNYFPKSLVPILLAFISKPNRVLENNASARHTLLHNLHNL	Refseq >NP_001080230|RAN GTPase activating protein 1 [Xenopus laevis] MAAEDIAQLADCLAKAKVGEGELSFKGKTLKLNTAQDAEEVIREIEEFEGLQALRLEGNTVGVEAAKVIAKALEKKSDLKRCHWSDMFTGRLRSEIPPALISLGDALITAGAQLTELDLSDNAFGPDGVRGFEALLKSPTCFTLQELKLNNCGMGIGGGKILAAALTECYKKSSSHGKPLALKVFIAGRNRLENDGATALSEAFRLIGSLEEVHMPQNGINHAGITALADSFKANSLLKVINLNDNTFTEKGGIAMAEALKTLRQVEVINFGDCLVRSKGAQAIASALKEGLHKLKELNLSFCEIKRDAAVSLAESVEDKSDLEKLDLNGNCLGEGGCEQVQEILDGINMANILGSLSDDEGDEDEDEVDDDDDDDDDEDDDDDDDDDEEEVEEEEEEVEGGDDDDNEEKSKKILSHASTPASPPKLPVDVSTFLSFPSPDKLVRMGPKRSTMIAQQVNVSDTEKVVQAFIQVSSVYRDEGEIKAAVEETIDGLMKEAFQNTGFQACLFITNLLVHMGLLKSEDKIKTITHLNGPLLTLNHMVQQNYFPKSLVPILLAFISKPNRVLENNASARHTLLHNLHNL		Refseq >NP_001165668|ran GTPase-activating protein 1 [Xenopus laevis] MAAEDIAQLADCLAKANVGDGELSFKGKTLKLNTAQDAEEVIREIEEYEGLQALRLEGNTVGVEAAKAIAEVLQRKPDLKRCHWSDMFTGRLRPEIPTALRSLGDALITAGAQLTELDLSDNAFGPDGVRGFEALLKSPTCFTLQELKLNNCGMGIGGGKILAAALTECHKKSSAHGKPLALKVFIAGRNRLENDGATALSEAFRLIGTLEEVHMPQNGINHAGITALAESFKANSLLKVINLNDNTFTEKGGVAMAEALKTLRQVEVINFGDCLVRSKGAQAIASALKEGLHKLKDLNLSYCEIKADAAVSLVESVEDKSDLEKLDLNGNCLGEEGCEQVQEILESINMANILGSLSDDEGDEDEDDDDDDDDDDDEDEDDDENDDEEVEEEEEEVEEEEGGDNENKEKSKEIPCLSGSAPASPPKLPVDASTFLSFPSPEKLVRMGPRRSAMIAQQVNVADTEKVVQAFIQVSSVYREDGEIKAAVEETIDGLMKEAFENRGFQANVFITSLLVQMGLLKSEDKMKTIPHLNGPLLTLNHMVQQNYFPKSLASTLLAFISKPNGVLENNASARHTLLCNLHNL UniProtKB

Genomic		tropicalis
Genome Browser		Xenbase	Xenbase JGI Ensembl UCSC		Xenbase
Synteny		Metazome

Expression		tropicalis	laevis a		laevis b
UniGene			Xl.14056		Xl.57165
Unigene EST Profile			EST Profile		EST Profile
GEO data			GEO		GEO
Images		0 expression image(s) for tropicalis and laevis

Orthology		MOD	Entrez Gene	Genetic Phenotypes	Morphants
human		OMIM:Gene, HGNC	RANGAP1
mouse		MGI	Rangap1	All(3) Gene Trapped(1) Targeted, other(2)
zebrafish		ZFIN	rangap1b

Publications
First:		Interaction of the nuclear GTP-binding protein Ran with its regulatory proteins RCC1 and RanGAP1. [Biochemistry 1995]
Most recent:		Subgroup II PAK-mediated phosphorylation regulates Ran activity during mitosis. [J Cell Biol 2010]
		View All Papers

Functional Ontologies
GO: Molecular:
Biological:
Cellular Component:
EC:
KOG:		[AYT] Ran GTPase-activating protein

Reagents		tropicalis	laevis a		laevis b
Clones			open biosystems		open biosystems
			geneservice/RZPD imagenes		geneservice/RZPD imagenes
Affymetrix 1.0			Xl.14056.1.S1_at		Xl.5282.1.S1_at
Affymetrix 2.0			Xl2.14056.1.S1_at		Xl2.5282.1.S1_at [+] Xl2.5282.2.A1_at

Symbol legend[+]

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