Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Summary Expression Gene Literature (68) GO Terms (28) Nucleotides (313) Proteins (21) Interactants (441) Wiki
XB-GENEPAGE-490007

Gene Symbol: cav1

Gene Name: caveolin 1

Synonyms: caveolin-1 , Cav-1 , cgl3 , bscl3 , vip21 , cav1-a , cav1-b ( Add Xenopus synonyms , Nomenclature history )

Gene Function: caveolar plasma membrane protein

Protein Function :
May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity.

Interactants: Loading ...
Disease Ontology: congenital generalized lipodystrophy type 3

OMIM Diseases: LIPODYSTROPHY, CONGENITAL GENERALIZED, TYPE 3; CGL3 [+]

1/2
 
Xenbase Gene ID XB-GENE-490008 XB-GENE-865922 XB-GENE-6254656
Gene Symbol cav1 cav1.L cav1.S
Chromosome Chr03 chr3L chr3S
Molecules tropicalis laevis.L laevis.S
Gene Genomic sequence Genomic sequence Genomic sequence
CDS Gene model
Entrez Gene
Entrez Gene
Entrez Gene
mRNA Refseq Refseq Refseq
Protein Refseq TrEMBL TrEMBL Refseq TrEMBL Refseq TrEMBL
Genomic tropicalis laevis.L laevis.S
Genome Browser
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics tropicalis laevis.L laevis.S
Embryonic Protein Expression Stage profile:
Data Mining tropicalis laevis.L laevis.S
XenMine cav1 cav1.L cav1.S
Phenotype tropicalis laevis.L laevis.S
Smith Morpholino Screen    
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM:Gene, HGNC, GeneCards CAV1 OMIM, MalaCards, KEGG Disease, DECIPHER Ensembl, Protein Atlas, Allen Brain Atlas
mouse
MGI, AGR Cav1 MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
zebrafish
ZFIN, AGR cav1 ZFIN Ensembl
chicken
GEISHA CAV1 Ensembl
fruit fly
worm
WORMBASE
Publications
First Multiple structural elements contribute to voltage-dependent facilitation of neuronal alpha 1C (CaV1.2) L-type calcium channels., Neuropharmacology 2001  
Most Recent Peripheral nerve injury increases contribution of L-type calcium channels to synaptic transmission in spinal lamina II: Role of α2δ-1 subunits., Mol Pain 2018            
All View All Papers 5 paper(s) referencing morpholinos 2 paper(s) referencing OMIMs 4 paper(s) referencing Disease Ontology
Functional Ontologies tropicalis laevis.L laevis.S
GO 26 terms 4 terms 6 terms
PANTHER cav1
KEGG Pathways K06278 K06278 K06278
KOG
Reagents tropicalis laevis.L laevis.S
CRISPR / TALEN CRISPR tools CRISPR tools CRISPR tools
Clones
Dharmacon Dharmacon Dharmacon
Antibody cav1 Ab1 cav1 Ab1 cav1 Ab1
ORF cav1.L ORF1 cav1.S ORF1
Affymetrix 1.0 Str.50490.1.A1_at Xl.22006.1.S1_at [+]
Affymetrix 2.0 Xl2.22006.1.S2_at Xl2.33299.1.S1_at

Symbol legend: - Blast this sequence    - View this sequence       - Literature or expression images  
Xenbase: The Xenopus laevis and X. tropicalis resource.
Version: 4.11.2


Major funding for Xenbase is provided by grant P41 HD064556