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Summary Expression Gene Literature (65) GO Terms (16) Nucleotides (313) Proteins (21) Interactants (403) Wiki
XB-GENEPAGE- 490007

Gene Symbol: cav1

Gene Name: caveolin 1

Synonyms: caveolin-1 , Cav-1 , cgl3 , bscl3 , vip21 , cav1-a , cav1-b
Add Xenopus synonyms , Nomenclature history


Gene Function: caveolar plasma membrane protein

Protein Function :
May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity.


Interactants: Loading ...

Disease Ontology:
   CONGENITAL GENERALIZED LIPODYSTROPHY TYPE 3

OMIM Diseases:
   LIPODYSTROPHY, CONGENITAL GENERALIZED, TYPE 3; CGL3 [+]
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Xenbase Gene ID XB-GENE-490008 XB-GENE-865922 XB-GENE-6254656
Gene Symbol cav1 cav1.L cav1.S
Chromosome Chr03 chr3L chr3S
Molecules tropicalis laevis.L laevis.S
Gene Genomic sequence Genomic sequence Genomic sequence
CDS Gene model
Entrez Gene
Entrez Gene
Entrez Gene
mRNA Refseq Refseq Refseq
Protein Refseq TrEMBL TrEMBL Refseq TrEMBL Refseq TrEMBL
Genomic tropicalis laevis.L laevis.S
Genome Browser
Links
Genomic Synteny Genomicus PANTHER
Expression tropicalis laevis.L laevis.S
Ensembl Ensembl
UniGene Str.58354 Xl.22006 Xl.70144
RNA-Seq profile Stage profile: Stage profile:       Tissue heatmap:
Experimental regulation Regulation heatmap:
Images 64 expression image(s) for tropicalis and laevis
Data Mining tropicalis laevis.L laevis.S
XenMine cav1 cav1.L cav1.S
Phenotype tropicalis laevis.L laevis.S
Smith Morpholino Screen    
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM:Gene, HGNC, GeneCards CAV1 OMIM, MalaCards, KEGG Disease, DECIPHER Ensembl, Protein Atlas, Allen Brain Atlas
mouse
MGI, AGR Cav1 MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
zebrafish
ZFIN, AGR cav1 ZFIN Ensembl
chicken
GEISHA CAV1 Ensembl
fruit fly
worm
WORMBASE
Publications
First: Multiple structural elements contribute to voltage-dependent facilitation of neuronal alpha 1C (CaV1.2) L-type calcium channels. [Neuropharmacology 2001]
Most recent: Innate Immune Response and Off-Target Mis-splicing Are Common Morpholino-Induced Side Effects in Xenopus. [Dev Cell 2018]
View All Papers 5 paper(s) referencing morpholinos 1 paper(s) referencing OMIMs 3 paper(s) referencing Disease Ontology
Functional Ontologies tropicalis laevis.L laevis.S
GO 14 terms 4 terms 6 terms
PANTHER cav1
KEGG Pathways K06278 K06278 K06278
KOG
Reagents tropicalis laevis.L laevis.S
CRISPR / TALEN CRISPR tools CRISPR tools CRISPR tools
Clones
GE Dharmacon GE Dharmacon GE Dharmacon
Source BioScience Source BioScience Source BioScience
ORF cav1.L ORF1 cav1.S ORF1
Affymetrix 1.0 Str.50490.1.A1_at Xl.22006.1.S1_at [+]
Affymetrix 2.0 Xl2.22006.1.S2_at Xl2.33299.1.S1_at

Symbol legend[+]
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Major funding for Xenbase is provided by the National Institute of Child Health and Human Development, grant P41 HD064556