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Summary Expression Gene Literature (21) GO Terms (9) Nucleotides (53) Proteins (26) Interactants (312) Wiki
XB-GENEPAGE-490074

Gene Symbol: lhx3

Gene Name: LIM homeobox 3

Synonyms: LIM-3 , xLIM-3 , lim3 ( Add synonyms , Nomenclature history )

Gene Function: LIM and homeodomain containing transcription factor

Protein Function :
May be involved in the specification and maintenance of differentiation of distinct neuronal and neuroendocrine tissues. Early marker for the pituitary and pineal lineages, it may be involved in specif...[+]

Interactants: Loading ...
Disease Ontology: hypopituitarism

OMIM Diseases: PITUITARY HORMONE DEFICIENCY, COMBINED, 2; CPHD2 [+]

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Xenbase Gene ID XB-GENE-490075 XB-GENE-865930 XB-GENE-17344008
Gene Symbol lhx3 lhx3.L lhx3.S
Chromosome Chr02 chr8L chr8S
Molecules tropicalis laevis.L laevis.S
Gene Genomic sequence Genomic sequence Genomic sequence
CDS Gene model
Entrez Gene
Entrez Gene
mRNA NCBI Nucleotide RefSeq
Protein NCBI Protein TrEMBL RefSeq TrEMBL Swiss-Prot
Genomic tropicalis laevis.L laevis.S
Genome Browser
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics tropicalis laevis.L laevis.S
Embryonic Protein Expression
Data Mining tropicalis laevis.L laevis.S
XenMine lhx3 lhx3.L lhx3.S
Phenotype tropicalis laevis.L laevis.S
Smith Morpholino Screen    
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM:Gene, HGNC, GeneCards LHX3 OMIM, MalaCards, KEGG Disease, DECIPHER Ensembl, Protein Atlas, Allen Brain Atlas
mouse
MGI, AGR Lhx3 MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
zebrafish
ZFIN, AGR lhx3 ZFIN Ensembl
chicken
GEISHA LHX3 Ensembl
fruit fly
worm
WORMBASE
Publications
First Expression of LIM class homeobox gene Xlim-3 in Xenopus development is limited to neural and neuroendocrine tissues., Dev Biol 1993                
Most Recent Conservatism and variability of gene expression profiles among homeologous transcription factors in Xenopus laevis., Dev Biol 2017                            
All View All Papers 4 paper(s) referencing morpholinos 1 paper(s) referencing OMIMs 1 paper(s) referencing Disease Ontology
Functional Ontologies tropicalis laevis.L laevis.S
GO 8 terms 5 terms 0 term
PANTHER lhx3
KEGG Pathways K09374
KOG [K] Transcription factor LIM3, contains LIM and HOX domains
Reagents tropicalis laevis.L laevis.S
CRISPR / TALEN CRISPR tools CRISPR tools CRISPR tools
Clones
Dharmacon Dharmacon Dharmacon
Affymetrix 1.0 Str.26236.1.S1_at [+] Xl.32.1.S1_at
Affymetrix 2.0 Xl2.32.1.S1_at

Symbol legend: - Blast this sequence    - View this sequence       - Literature or expression images  
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