Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Summary Expression Gene Literature (20) GO Terms (19) Nucleotides (63) Proteins (21) Interactants (283) Wiki
XB-GENEPAGE-490223
Gene Symbol:
shroom3

Gene Name:
shroom family member 3

Synonyms:
shrm , shroom , apxl3 ( Add synonyms , Nomenclature history )

Gene Function:


Protein Function :
Controls cell shape changes in the neuroepithelium during neural tube closure (PubMed:14680628). Induces apical constriction in epithelial cells by promoting the apical accumulation of F-actin and myos...[+]



Interactants:
Loading ...

Diseases: 


External Links:
1/9
 
Xenbase Gene ID XB-GENE-490224 XB-GENE-490228 XB-GENE-17346032
Gene Symbol shroom3 shroom3.L shroom3.S
Chromosome Chr01 chr1L
Molecules tropicalis laevis.L laevis.S
Genomic Sequence Version 9.1 Version 9.2
CDS Gene model Gene model
Entrez Gene 100491559
734194
mRNA NCBI Nucleotide RefSeq
Protein NCBI Protein RefSeq
Genomic
tropicalis laevis.L laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Data Mining tropicalis laevis.L laevis.S
XenMine shroom3 shroom3.L shroom3.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards SHROOM3 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Shroom3 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Shroom3 Ensembl
zebrafish
ZFIN, AGR shroom3 ZFIN Ensembl
chicken
GEISHA SHROOM3 Ensembl
fruit fly
worm
Publications
First Shroom induces apical constriction and is required for hingepoint formation during neural tube closure., Curr Biol 2003                            
Most Recent Anillin regulates epithelial cell mechanics by structuring the medial-apical actomyosin network., Elife 2019                                
All View All Papers 6 paper(s) referencing morpholinos 2 paper(s) referencing OMIMs 1 paper(s) referencing Disease Ontology
Functional Ontologies tropicalis laevis.L laevis.S
GO 11 terms 14 terms 0 term
PANTHER shroom3
KEGG Pathways K18625
KOG
Reagents tropicalis laevis.L laevis.S
CRISPRscan Tracks shroom3
Mutants Xtr.shroom3emHorb
Morpholinos shroom3 MO1 shroom3 MO1 shroom3 MO1
Clones EXRC Horizon Source BioScience Horizon Source BioScience

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info   [+] Expand list
Xenbase: The Xenopus Model Organism Knowledgebase.
Version: 4.14.0
Major funding for Xenbase is provided by grant P41 HD064556