lhx2 Summary [species: Xenopus laevis and Xenopus tropicalis] - Xenbase Gene Catalog

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Summary

Gene Literature (12)

Nucleotides (47)

Interactants (81)

XB-GENEPAGE-490330

Gene Symbol: lhx2 Gene Name: LIM homeobox 2 Synonyms: x-Lhx2, XLhx2 Add Xenopus synonyms Gene Function: homeodomain transcription factor Interactants: pax6(7) , lhx9(6) , lhx1(5) , otx2(5) , rax(5) , lhx5(4) , six6(4) View All

XB-GENE-490331

XB-GENE-865959

XB-GENE-6252391

Molecules		tropicalis	laevis a		laevis b
Gene		JGI XT Genome 7.1 JGI XT Genome 4.1 Ensembl 4.1	JGI XL Genome 6.0
		Entrez Gene	Entrez Gene		Entrez Gene
mRNA		NCBI Nucleotide >XM_002938749\|PREDICTED: Xenopus (Silurana) tropicalis LIM/homeobox protein Lhx2-like (LOC100486746), mRNA ATGGAATTAGGCTACCAAAGCTTCTGTCAGATTTCCCACGCGTGTCATTTCCACGCTGCAGAGATGCTTTTCCACAGTCTATCAGGGGGGGAGATGCATGGGGTCATCGATGAGATGGACAGAAGGAGCAAGAACGAAGTGTCGGCTATCAGCTCTGCAATTGATAGAGGGGAGACTGAGACGACTATGCCATCCATCAGCAGTGACCGGGCCGCACTCTGTGCAGGGTGTGGAGGGAAGATTTCAGACCGGTACTACCTCTTGGCAGTTGACAAACAATGGCATATGCGTTGCCTAAAGTGCTGTGAATGTAAATTAAACCTGGAGTCGGAGCTTACCTGCTTCAGCAAAGATGGAAGCATATACTGCAAAGAGGACTATTACAGGCGATTTTCAGTCCAAAGATGTGCCAGGTGCCACTTGGGAATCTCTGCCTCTGAGATGGTAATGAGAGCCAGGGACTTAGTGTATCACCTCAACTGCTTTACCTGCAACACTTGCAACAAGATGCTCACCACTGGGGACCATTTTGGCATGAAGGACAATTTAGTATACTGCCGGCTCCACTTTGAGACTTTGATACAGGGAGAATACCAAGTTCACTTCAGTCACTCGGATGTAGCATCAGGGAAGGGCTCAGGACTTGGCACAGGGGCTGCCTCTTTGGGGCTGCCTTACTACAATGGCGTGGGAACTGTCCAGAAAGGGAGACCGAGAAAGAGGAAAAGCCCAGGTCCTGGGGCGGACTTGGCTGCCTACAACGCAGCTCTGAGCTGCAATGAAAATGATGGAGACCATATGGATAGAGACCAGCAGTACACGCCGAATCAGAAAACCAAAAGAATGAGGACCTCCTTCAAACACCATCAGCTACGAACAATGAAGTCCTACTTTGCTATCAACCACAACCCAGATGCCAAGGACCTAAAGCAGCTAGCTCAGAAGACAGGTTTAACCAAAAGGGTTTTACAGGTATGGTTTCAGAATGCACGAGCCAAATTCAGAAGGAATCTCCTGCGACAAGAAAACAATGGAGTGGACAAAACATCTGATTCCACACTTCAAGCTGGAACTCCATCAGGGCCAGCGTCTGAAATCTCCAATGCCTCCATGAGTCCATCTAGCACCCCAACAACGTTAACAGACTTGACTAACCCTACCATGCCAACTGTGACCTCTGTACTGACATCGGTGCCTGGCAACTTGGACGTACACGAGTCTCGAAGCCCTCCCCAAACAACTCTTACAAATCTCTTCTGA	NCBI Nucleotide >AJ311712\|Xenopus laevis partial mRNA for Lhx2 protein (Lhx2 gene), N-terminal TTGCGTTGCCTGAAGTGCTGTGAATGTAAATTAAACCTGGAGTCGGAGCTTACCTGCTTTAGCAAAGACGGAAGTATATACTGCAAGGAGGACTATTACAGGCGATTTTCAGTCCAGAGATGCGCCAGATGCCACTTGGGAATCTCTGCCTCTGAGATGGTAATGAGAGCCAGGGACTTAGTGTATCACCTCAACTGCTTTACCTGCAACACTTGCAACAAGATGCTCACCACTGGGGACCATTTTGGGATGAAGGACAATTTAGTATACTGCCGGCTCCACTTTGAGACTTTGATACAGGGAGAATACCAAGTTCATTTCGGTCACTCGGATGTAGCATCAAGGAAGGGCTCAGGGGCTACCTCTTTGGGGCTG		NCBI Nucleotide >AJ311713\|Xenopus laevis partial mRNA for Lhx2 protein (Lhx2 gene), C-terminal TGCGTGGACATGTCCAGAAGGGGAGACCAAGAAAGAGAAAAAGTCCAGGTTCTGGGGCGGATCTAGCTGCCTACAACGCAGCTCTAAGCTTCAATGAAAATGATGGAGACCATATGGATAGAGACCAGCAGTACACGCCCAATCAGAAAACCAAAAGAATGAGGACCTCCTTCAAACACCATCAGCTACGAACAATGAAGTCCTACTTTGCTATCAACCACAATCCAGATGCCAAGGACTTAAAGCAGTTAGCTCAGAAGACAGGTTTAACCAAAAGGGTTTTGCAGGTA
Protein		NCBI Protein >XP_002938795\|PREDICTED: LIM/homeobox protein Lhx2-like [Xenopus (Silurana) tropicalis] MELGYQSFCQISHACHFHAAEMLFHSLSGGEMHGVIDEMDRRSKNEVSAISSAIDRGETETTMPSISSDRAALCAGCGGKISDRYYLLAVDKQWHMRCLKCCECKLNLESELTCFSKDGSIYCKEDYYRRFSVQRCARCHLGISASEMVMRARDLVYHLNCFTCNTCNKMLTTGDHFGMKDNLVYCRLHFETLIQGEYQVHFSHSDVASGKGSGLGTGAASLGLPYYNGVGTVQKGRPRKRKSPGPGADLAAYNAALSCNENDGDHMDRDQQYTPNQKTKRMRTSFKHHQLRTMKSYFAINHNPDAKDLKQLAQKTGLTKRVLQVWFQNARAKFRRNLLRQENNGVDKTSDSTLQAGTPSGPASEISNASMSPSSTPTTLTDLTNPTMPTVTSVLTSVPGNLDVHESRSPPQTTLTNLF	NCBI Protein >CAC35215\|Lhx2 protein [Xenopus laevis] LRCLKCCECKLNLESELTCFSKDGSIYCKEDYYRRFSVQRCARCHLGISASEMVMRARDLVYHLNCFTCNTCNKMLTTGDHFGMKDNLVYCRLHFETLIQGEYQVHFGHSDVASRKGSGATSLGL		NCBI Protein >CAC35216\|Lhx2 protein [Xenopus laevis] RGHVQKGRPRKRKSPGSGADLAAYNAALSFNENDGDHMDRDQQYTPNQKTKRMRTSFKHHQLRTMKSYFAINHNPDAKDLKQLAQKTGLTKRVLQV

Genomic		tropicalis
Genome Browser		Xenbase	Xenbase JGI Ensembl UCSC		Xenbase

Synteny		Metazome

Expression		tropicalis	laevis a		laevis b
UniGene			Xl.85824 [+] Xl.74690 Xl.80009		Xl.21557
Unigene EST Profile			EST Profile		EST Profile
GEO data			GEO		GEO
Images		9 expression image(s) for tropicalis and laevis

Orthology		MOD	Entrez Gene	Genetic Phenotypes	Morphants
human		OMIM:Gene, HGNC	LHX2
mouse		MGI	Lhx2	All(9) Targeted, knock Out(3) Targeted, other(5)
zebrafish		ZFIN ZFIN	lhx2a lhx2b	8 Lines(s)

Publications
First:		The LIM-homeodomain gene family in the developing Xenopus brain: conservation and divergences with the mouse related to the evolution of the forebrain. [J Neurosci 2001]
Most recent:		The role of miR-124a in early development of the Xenopus eye. [Mech Dev 2009]
		View All Papers 1 paper(s) referencing morpholinos

Functional Ontologies
GO: Molecular:		DNA binding transcription factor activity zinc ion binding
Biological:		regulation of transcription, DNA-dependent
Cellular Component:		nucleus
EC:
KOG:		[R] Transcription factor, contains HOX domain

Reagents		tropicalis	laevis a		laevis b
Clones			open biosystems		open biosystems
			geneservice/RZPD imagenes		geneservice/RZPD imagenes
Affymetrix 1.0		Str.40811.1.S1_s_at [+] Str.40811.1.S1_at StrEns.6799.1.S1_at	Xl.21558.1.S1_at [+] Xl.21558.1.A1_at Xl.11793.1.A1_at		Xl.21557.1.S1_at [+] Xl.21557.1.A1_at
Affymetrix 2.0			Xl2.47900.1.A1_at		Xl2.21557.1.A1_at [+] Xl2.21557.1.S1_x_at

Symbol legend[+]