Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Summary Expression Gene Literature (32) GO Terms (9) Nucleotides (98) Proteins (25) Interactants (434) Wiki
XB-GENEPAGE- 490399

Gene Symbol: lhx5

Gene Name: LIM homeobox 5

Synonyms: xlim-5 , xlim-2a , Xlim5
Add Xenopus synonyms , Nomenclature history


Gene Function: LIM and homeodomain containing transcription factor

Protein Function:
Probably involved in the patterning of the nervous system, in particular in the early specification of the diencephalon.


Interactants: Loading ...

OMIM Disease Associations:
 
Xenbase Gene ID XB-GENE-490400 XB-GENE-17330956 XB-GENE-865965
Gene Symbol lhx5 lhx5.L lhx5.S
Chromosome Chr01 chr1L chr1S
Molecules tropicalis laevis.L laevis.S
Gene GBrowse 8.0 JBrowse 8.0 GBrowse 7.1 JBrowse 7.1 GBrowse 4.1 JGI Genome 4.1 Ensembl 4.1 GBrowse 9.1 JBrowse 9.1 GBrowse 9.1 JBrowse 9.1 GBrowse 7.2 JBrowse 7.2 GBrowse 6.0
Entrez Gene
Entrez Gene
mRNA Refseq Refseq
Protein Refseq TrEMBL Refseq Swiss-Prot
Genomic tropicalis laevis.L laevis.S
Genome Browser
Links
Genomic Synteny Genomicus   Metazome
Expression tropicalis laevis.L laevis.S
Ensembl Ensembl
UniGene Str.14655 [+] Xl.1047 [+]
RNA-Seq profile Stage profile: Stage profile:       Tissue heatmap:
Experimental regulation Regulation heatmap:
Images 11 expression image(s) for tropicalis and laevis
Data Mining tropicalis laevis.L laevis.S
XenMine lhx5 lhx5.L lhx5.S
Phenotype tropicalis laevis.L laevis.S
Smith Morpholino Screen    
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM:Gene, HGNC, GeneCards LHX5 OMIM, MalaCards, KEGG Disease, DECIPHER Ensembl, Protein Atlas, Allen Brain Atlas
mouse
MGI Lhx5 MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
zebrafish
ZFIN lhx5 ZFIN Ensembl
chicken
GEISHA LHX5 Ensembl
fruit fly
worm
WORMBASE
Publications
First: The LIM class homeobox gene lim5: implied role in CNS patterning in Xenopus and zebrafish. [Dev Biol 1995]
Most recent: Conservatism and variability of gene expression profiles among homeologous transcription factors in Xenopus laevis. [Dev Biol 2017]
View All Papers 5 paper(s) referencing morpholinos 1 paper(s) referencing OMIMs
Functional Ontologies tropicalis laevis.L laevis.S
GO 7 terms 0 term 7 terms
EC
PANTHER lhx5
KEGG Pathways K18493 K18493
KOG [K] Transcription factor LIM3, contains LIM and HOX domains
Reagents tropicalis laevis.L laevis.S
CRISPR / TALEN CRISPR tools CRISPR tools CRISPR tools
Clones
GE Dharmacon GE Dharmacon GE Dharmacon
Source BioScience Source BioScience
Morpholino lhx5 MO1 lhx5 MO1 lhx5 MO1
ORF lhx5 ORF1
Affymetrix 1.0 Str.14655.1.S1_at [+] Xl.1047.1.S1_at [+]
Affymetrix 2.0 Xl2.21652.1.S1_at [+]

Symbol legend[+]

My Xenbase: [ Log-in / Register ]
version: [4.6.0]

Major funding for Xenbase is provided by the National Institute of Child Health and Human Development, grant P41 HD064556