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Summary Expression Gene Literature (20) GO Terms (11) Nucleotides (75) Proteins (30) Interactants (317) Wiki
XB-GENEPAGE-491113

Gene Symbol: dicer1

Gene Name: dicer 1, ribonuclease III

Synonyms: dicer , dcr1 , herna ( Add Xenopus synonyms , Nomenclature history )

Gene Function: double-strand-specific ribonuclease

Protein Function :
Double-stranded RNA (dsRNA) endoribonuclease playing a central role in short dsRNA-mediated post-transcriptional gene silencing. Cleaves naturally occurring long dsRNAs and short hairpin pre-microRNAs ...[+]

Interactants: Loading ...
Disease Ontology: multinodular goiter [+]

OMIM Diseases: GOITER, MULTINODULAR 1, WITH OR WITHOUT SERTOLI-LEYDIG CELL TUMORS; MNG1 [+]

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Xenbase Gene ID XB-GENE-491114 XB-GENE-17331064 XB-GENE-6460379
Gene Symbol dicer1 dicer1.L dicer1.S
Chromosome Chr08 chr8L chr8S
Molecules tropicalis laevis.L laevis.S
Gene Genomic sequence Genomic sequence Genomic sequence
CDS Gene model
Entrez Gene
Entrez Gene
Entrez Gene
mRNA RefSeq NCBI Nucleotide RefSeq
Protein RefSeq TrEMBL Swiss-Prot NCBI Protein TrEMBL RefSeq TrEMBL
Genomic tropicalis laevis.L laevis.S
Genome Browser
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics tropicalis laevis.L laevis.S
Embryonic Protein Expression Stage profile: Stage profile:
Data Mining tropicalis laevis.L laevis.S
XenMine dicer1 dicer1.L dicer1.S
Phenotype tropicalis laevis.L laevis.S
Smith Morpholino Screen    
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM:Gene, HGNC, GeneCards DICER1 OMIM, MalaCards, KEGG Disease, DECIPHER Ensembl, Protein Atlas, Allen Brain Atlas
mouse
MGI, AGR Dicer1 MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
zebrafish
ZFIN, AGR dicer1 ZFIN Ensembl
chicken
GEISHA DICER1 Ensembl
fruit fly
worm
WORMBASE
Publications
First Exonucleolytic degradation of double-stranded RNA by an activity in Xenopus laevis germinal vesicles., Proc Natl Acad Sci U S A 2003  
Most Recent Endodermal Maternal Transcription Factors Establish Super-Enhancers during Zygotic Genome Activation., Cell Rep 2019                            
All View All Papers 2 paper(s) referencing morpholinos 2 paper(s) referencing OMIMs
Functional Ontologies tropicalis laevis.L laevis.S
GO 10 terms 5 terms 6 terms
PANTHER dicer1
KEGG Pathways K11592 K11592 K11592
KOG [A] dsRNA-specific nuclease Dicer and related ribonucleases
Reagents tropicalis laevis.L laevis.S
CRISPR / TALEN CRISPR tools CRISPR tools CRISPR tools
Clones
Dharmacon Dharmacon Dharmacon
Antibody Dicer1 Ab1 Dicer1 Ab1 Dicer1 Ab1
Morpholino dicer1 MO1 , dicer1 MO2 , dicer1 MO3 , dicer1 MO4 , dicer1 MO5 dicer1 MO1 , dicer1 MO2 , dicer1 MO3 , dicer1 MO4 , dicer1 MO5 dicer1 MO1 , dicer1 MO2 , dicer1 MO3 , dicer1 MO4 , dicer1 MO5
Affymetrix 1.0 StrJgi.2481.1.S1_s_at [+]
Affymetrix 2.0

Symbol legend: - Blast this sequence    - View this sequence       - Literature or expression images  
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