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Summary Expression Gene Literature (270) GO Terms (6) Nucleotides (228) Proteins (24) Interactants (990) Wiki
XB-GENEPAGE- 491120

Gene Symbol: tubb2b

Gene Name: tubulin beta 2B class IIb

Synonyms: n-tubulin , ntubulin , Xn-tubulin , N-Tub , neural beta-tubulin , NBT , NST
Add Xenopus synonyms , Nomenclature history


Gene Function: microtubule component

Protein Function:
Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.


Interactants: Loading ...

OMIM Disease Associations: POLYMICROGYRIA, SYMMETRIC OR ASYMMETRIC; PMGYSA
1/12
 
Xenbase Gene ID XB-GENE-491121 XB-GENE-17340462 XB-GENE-866032
Gene Symbol tubb2b tubb2b.L tubb2b.S
Chromosome Chr06 chr6L chr6S
Molecules tropicalis laevis.L laevis.S
Gene GBrowse 8.0 JBrowse 8.0 GBrowse 7.1 JBrowse 7.1 GBrowse 4.1 JGI Genome 4.1 Ensembl 4.1 GBrowse 9.1 JBrowse 9.1 GBrowse 9.1 JBrowse 9.1 GBrowse 7.2 JBrowse 7.2 GBrowse 6.0
Entrez Gene
Entrez Gene
mRNA Refseq Refseq
Protein Refseq TrEMBL Refseq Swiss-Prot TrEMBL
Genomic tropicalis laevis.L laevis.S
Genome Browser
Links
Genomic Synteny Genomicus   Metazome
Expression tropicalis laevis.L laevis.S
Ensembl Ensembl
UniGene Str.5452 Xl.121 [+]
RNA-Seq profile Stage profile: Stage profile:       Tissue heatmap:
Experimental regulation Regulation heatmap:
Images 260 expression image(s) for tropicalis and laevis
Data Mining tropicalis laevis.L laevis.S
XenMine tubb2b tubb2b.L tubb2b.S
Phenotype tropicalis laevis.L laevis.S
Smith Morpholino Screen    
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
TUBB2B OMIM, MalaCards, KEGG Disease, DECIPHER Ensembl, Protein Atlas, Allen Brain Atlas
mouse
MGI Tubb2b MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
zebrafish
ZFIN tubb2b ZFIN Ensembl
chicken
GEISHA TUBB2B Ensembl
fruit fly
worm
WORMBASE
Publications
First: Gene expression in the embryonic nervous system of Xenopus laevis. [Proc Natl Acad Sci U S A 1988]
Most recent: Six1 and Eya1 both promote and arrest neuronal differentiation by activating multiple Notch pathway genes. [Dev Biol 2017]
View All Papers 83 paper(s) referencing morpholinos 3 paper(s) referencing OMIMs
Functional Ontologies tropicalis laevis.L laevis.S
GO 6 terms 0 term 6 terms
EC
PANTHER tubb2b
KEGG Pathways K07375 K07375
KOG [Z] Beta tubulin
Reagents tropicalis laevis.L laevis.S
CRISPR / TALEN CRISPR tools CRISPR tools CRISPR tools
Clones EXRC - 1 clone(s)   EXRC - 1 clone(s)
GE Dharmacon GE Dharmacon GE Dharmacon
Source BioScience Source BioScience
Antibody Tubb2b Ab1 , Tubb2b Ab2 , Tubb2b Ab3 , Tubb2b Ab4 , Tubb2b Ab5 Tubb2b Ab1 , Tubb2b Ab2 , Tubb2b Ab3 , Tubb2b Ab4 , Tubb2b Ab5
ORF tubb2b ORF1
Affymetrix 1.0 Str.39273.2.S1_a_at [+] Xl.121.1.S1_at
Affymetrix 2.0 Xl2.121.1.S1_at

Symbol legend[+]

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