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Summary Expression Gene Literature (321) GO Terms (8) Nucleotides (231) Proteins (24) Interactants (1645) Wiki
XB-GENEPAGE-491120

Gene Symbol: tubb2b

Gene Name: tubulin beta 2B class IIb

Synonyms: n-tubulin , ntubulin , Xn-tubulin , N-Tub , neural beta-tubulin , NBT , NST ( Add synonyms , Nomenclature history )

Gene Function: microtubule component

Protein Function :
Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.

Interactants: Loading ...
Disease Ontology: complex cortical dysplasia with other brain malformations 7

OMIM Diseases: CORTICAL DYSPLASIA, COMPLEX, WITH OTHER BRAIN MALFORMATIONS 7; CDCBM7

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Xenbase Gene ID XB-GENE-491121 XB-GENE-17340462 XB-GENE-866032
Gene Symbol tubb2b tubb2b.L tubb2b.S
Chromosome Chr06 chr6L chr6S
Molecules tropicalis laevis.L laevis.S
Gene Genomic sequence Genomic sequence Genomic sequence
CDS Gene model
Entrez Gene
Entrez Gene
mRNA RefSeq RefSeq
Protein RefSeq TrEMBL RefSeq TrEMBL Swiss-Prot
Genomic tropicalis laevis.L laevis.S
Genome Browser
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics tropicalis laevis.L laevis.S
Embryonic Protein Expression Stage profile:
Data Mining tropicalis laevis.L laevis.S
XenMine tubb2b tubb2b.L tubb2b.S
Phenotype tropicalis laevis.L laevis.S
Smith Morpholino Screen    
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM:Gene, HGNC, GeneCards TUBB2B OMIM, MalaCards, KEGG Disease, DECIPHER Ensembl, Protein Atlas, Allen Brain Atlas
mouse
MGI, AGR Tubb2b MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
zebrafish
ZFIN, AGR tubb2b ZFIN Ensembl
chicken
GEISHA TUBB2B Ensembl
fruit fly
worm
WORMBASE
Publications
First Gene expression in the embryonic nervous system of Xenopus laevis., Proc Natl Acad Sci U S A 1988        
Most Recent Calcium Activity Dynamics Correlate with Neuronal Phenotype at a Single Cell Level and in a Threshold-Dependent Manner., Int J Mol Sci 2019                        
All View All Papers 91 paper(s) referencing morpholinos 7 paper(s) referencing OMIMs 12 paper(s) referencing Disease Ontology
Functional Ontologies tropicalis laevis.L laevis.S
GO 8 terms 0 term 6 terms
PANTHER tubb2b
KEGG Pathways K07375 K07375
KOG [Z] Beta tubulin
Reagents tropicalis laevis.L laevis.S
CRISPR / TALEN CRISPR tools CRISPR tools CRISPR tools
Clones EXRC - 1 clone(s)   EXRC - 1 clone(s)
Dharmacon Dharmacon Dharmacon
Antibody Tubb2b Ab1 , Tubb2b Ab2 , Tubb2b Ab3 , Tubb2b Ab4 , Tubb2b Ab5 , Tubb2b Ab6 , Tubb2b Ab8 Tubb2b Ab6 , Tubb2b Ab8 Tubb2b Ab1 , Tubb2b Ab2 , Tubb2b Ab3 , Tubb2b Ab4 , Tubb2b Ab5 , Tubb2b Ab6 , Tubb2b Ab8
ORF tubb2b ORF1 tubb2b.S ORF1
Affymetrix 1.0 Str.39273.2.S1_a_at [+] Xl.121.1.S1_at
Affymetrix 2.0 Xl2.121.1.S1_at

Symbol legend: - Blast this sequence    - View this sequence       - Literature or expression images  
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