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Summary Expression Gene Literature (13) GO Terms (4) Nucleotides (327) Proteins (36) Interactants (385) Wiki
XB-GENEPAGE- 491479

Gene Symbol: eed

Gene Name: embryonic ectoderm development

Synonyms: Xeed , wait1 , eed-a , eed-b , MGC82196
Add Xenopus synonyms , Nomenclature history


Gene Function: transcriptional repressor

Protein Function:
Polycomb group (PcG) protein. Component of the prc2/eed-ezh2 complex, which methylates 'Lys-9' and 'Lys-27' of histone H3, leading to transcriptional repression of the affected target gene. May play a ...[+]


Interactants: YYY

OMIM Disease Associations:
 
Xenbase Gene ID XB-GENE-491480 XB-GENE-6255887 XB-GENE-491484
Gene Symbol eed eed.L eed.S
Chromosome scaffold_2 chr2L chr2S
Molecules tropicalis laevis.L laevis.S
Gene GBrowse 7.1 JBrowse 7.1 GBrowse 4.1 JGI Genome 4.1 Ensembl 4.1 GBrowse 9.1 JBrowse 9.1 GBrowse 6.0 GBrowse 9.1 JBrowse 9.1 GBrowse 7.2 JBrowse 7.2 GBrowse 6.0
Entrez Gene
Entrez Gene
Entrez Gene
mRNA Refseq Refseq Refseq
Protein Refseq Swiss-Prot Refseq Swiss-Prot Refseq Swiss-Prot
Genomic tropicalis laevis.L laevis.S
Genome Browser
GBrowse
tropicalis genome v7.1 gene model
GBrowse
laevis genome v9.1 gene model
GBrowse
laevis genome v9.1 gene model
Links
Genomic Synteny Genomicus   Metazome
Expression tropicalis laevis.L laevis.S
Ensembl Ensembl
UniGene Str.46642 [+] Xl.5897 Xl.4736
RNA-Seq profile Stage profile: Stage profile:       Tissue heatmap:
Images 7 expression image(s) for tropicalis and laevis
Data Mining tropicalis laevis.L laevis.S
XenMine eed eed.L eed.S
Phenotype tropicalis laevis.L laevis.S
Smith Morpholino Screen tgas047c23      
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM:Gene, HGNC, GeneCards EED OMIM, MalaCards, KEGG Disease, DECIPHER Ensembl, Protein Atlas, Allen Brain Atlas
mouse
MGI Eed MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
zebrafish
ZFIN eed ZFIN Ensembl
chicken
GEISHA MIR6755 Ensembl
fruit fly
worm
WORMBASE
Publications
First: Regulation of Hoxb3 expression in the hindbrain and pharyngeal arches by rae28, a member of the mammalian Polycomb group of genes. [Mech Dev 2000]
Most recent: Sex chromosome differentiation and the W- and Z-specific loci in Xenopus laevis. [Dev Biol 2017]
View All Papers 2 paper(s) referencing morpholinos
Functional Ontologies tropicalis laevis.L laevis.S
GO 4 terms 4 terms 4 terms
EC
PANTHER eed
KEGG Pathways K11462 K11462 K11462
KOG [K] Transcriptional repressor EED/ESC/FIE, required for transcriptional silencing, WD repeat superfamily
Reagents tropicalis laevis.L laevis.S
CRISPR / TALEN CRISPR tools CRISPR tools CRISPR tools
Clones
GE Dharmacon GE Dharmacon GE Dharmacon
Source BioScience Source BioScience Source BioScience
Morpholino eed MO1 eed MO1 eed MO1
ORF eed ORF1
Affymetrix 1.0 Str.6112.1.S1_at [+] Xl.5897.1.S1_at Xl.4736.1.S1_at
Affymetrix 2.0 Xl2.5897.1.S1_at Xl2.4736.1.S2_s_at [+]

Symbol legend[+]

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