Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Summary Expression Gene Literature (12) GO Terms (9) Nucleotides (119) Proteins (38) Interactants (74) Wiki
XB-GENEPAGE-491964
Gene Symbol:
lox

Gene Name:
lysyl oxidase

Synonyms:
Xlox ( Add synonyms , Nomenclature history )

Gene Function:
copper-dependent amine oxidase

Protein Function :
Mediates the post-translational oxidative deamination of lysine residues on target proteins leading to the formation of deaminated lysine (allysine).


InterPro :
Csc1 N , PHM7 cyt , RSN1 7TM , Lysyl oxidase [+]

Interactants:
Loading ...

Diseases: 


Disease Ontology:
cutis laxa [+]

OMIM:
CUTIS LAXA, AUTOSOMAL RECESSIVE, TYPE IA; ARCL1A [+]

External Links:
1/3
 
Xenbase Gene ID XB-GENE-491965 XB-GENE-491969 XB-GENE-17342033
Gene Symbol lox lox.L lox.S
Chromosome Chr1 chr1L chr1S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.1 Version 9.1
CDS Gene model Gene model Gene model
Entrez Gene 780067
734204
108707204
mRNA RefSeq NCBI Nucleotide NCBI Nucleotide
Protein NCBI Protein RefSeq  More.. NCBI Protein RefSeq  More.. NCBI Protein TrEMBL
Genomic
 X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine lox lox.L lox.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards LOX OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Lox MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Lox Ensembl
zebrafish
ZFIN, AGR loxa ZFIN Ensembl
chicken
GEISHA LOX Ensembl
fruit fly
FLYBASE Loxl1 Ensembl
worm
Publications
First A recombinant adenovirus that directs secretion of biologically active kappa-bungarotoxin from mammalian cells., Brain Res Mol Brain Res 1997  
Most Recent Epigenetic control of myeloid cells behavior by Histone Deacetylase activity (HDAC) during tissue and organ regeneration in Xenopus laevis., Dev Comp Immunol 2021  
All View All Papers
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 9 terms 5 terms 5 terms
PANTHER lox
KEGG Pathways K00277 K00277 K00277
KOG
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks lox
ORFs lox ORF1 lox.L ORF1
Clones Horizon Source BioScience Horizon Source BioScience Horizon
Plasmids Addgene Addgene

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info