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XB-GENEPAGE-492019
Gene Symbol:
rlim
Gene Name: ring finger protein, LIM domain interacting
Synonyms:
XRnf12
,
rnf12
,
rnf12b
,
rlim-a
,
rlim-b
( Gene Function: mediator of ubiquitin ligase activity Protein Function
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Acts as an E3 ubiquitin-protein ligase specific for ldb1, mediating ubiquitination and proteasome-dependent degradation of excess ldb1 in a RING-dependent manner. Does not degrade ldb1 bound to lhx1/li...[+]
Interactants:
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Diseases: OMIM:
TONNE-KALSCHEUER SYNDROME; TOKAS
External Links:
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Xenbase Gene ID | XB-GENE-492020 | XB-GENE-6256130 | XB-GENE-866117 | |||||
Gene Symbol | rlim | rlim.L | rlim.S | Chromosome | Chr8 | chr8L | chr8S | |
Molecules | X. tropicalis | X. laevis.L | X. laevis.S | |||||
Genomic Sequence |
Version 10.0
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Version 9.1
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Version 9.1
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CDS |
Gene model
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Gene model
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Gene model
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Entrez Gene |
548845
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100137618
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398680
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mRNA |
RefSeq
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NCBI Nucleotide
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NCBI Nucleotide
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Protein
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Genomic |
X. tropicalis | X. laevis.L | X. laevis.S | |||||
Genome Browser (Click image to open in Genome Browser) |
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Genomic Synteny | Genomicus PANTHER | |||||||
Expression | Development Stages | Embryonic Tissues | Adult Tissues | |||||
Summary for |
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More Information |
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Proteomics | X. tropicalis | X. laevis.L | X. laevis.S | |||||
Embryonic Protein Expression | Stage profile:![]() |
Stage profile:![]() |
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Data Mining | X. tropicalis | X. laevis.L | X. laevis.S | |||||
XenMine | rlim | rlim.L | rlim.S | |||||
Orthology |
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human |
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mouse |
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rat |
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zebrafish |
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chicken |
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fruit fly |
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worm |
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Publications | ||||||||
First |
Selective degradation of excess Ldb1 by Rnf12/RLIM confers proper Ldb1 expression levels and Xlim-1/Ldb1 stoichiometry in Xenopus organizer functions., Development 2003 ![]() |
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Most Recent |
Conservatism and variability of gene expression profiles among homeologous transcription factors in Xenopus laevis., Dev Biol 2017 ![]() |
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All | View All Papers | |||||||
Functional Ontologies | X. tropicalis | X. laevis.L | X. laevis.S | |||||
GO | 15 terms | 8 terms | 9 terms | |||||
PANTHER | rlim | |||||||
KEGG Pathways | K16271 | K16271 | K16271 | |||||
KOG |
[O] FOG: Predicted E3 ubiquitin ligase
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Reagents | X. tropicalis | X. laevis.L | X. laevis.S | |||||
CRISPRscan Tracks | rlim | |||||||
ORFs | rlim.S ORF1 | |||||||
Clones | Horizon | Horizon Source BioScience | Horizon Source BioScience | |||||
Plasmids | Addgene | Addgene |
Symbol legend:



