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Summary Expression Gene Literature (24) GO Terms (16) Nucleotides (223) Proteins (49) Interactants (164) Wiki
XB-GENEPAGE-492019
Gene Symbol:
rlim

Gene Name:
ring finger protein, LIM domain interacting

Synonyms:
XRnf12 , rnf12 , rnf12b , rlim-a , rlim-b ( Add synonyms , Nomenclature history )

Gene Function:
mediator of ubiquitin ligase activity

Protein Function :
Acts as an E3 ubiquitin-protein ligase specific for ldb1, mediating ubiquitination and proteasome-dependent degradation of excess ldb1 in a RING-dependent manner. Does not degrade ldb1 bound to lhx1/li...[+]


InterPro :
WD40 repeat CS , WD40 repeat dom sf , WD40 repeat , SSU processome Utp12 [+]

Interactants:
Loading ...

Diseases: 


OMIM:
TONNE-KALSCHEUER SYNDROME; TOKAS

External Links:
 
Xenbase Gene ID XB-GENE-492020 XB-GENE-6256130 XB-GENE-866117
Gene Symbol rlim rlim.L rlim.S
Chromosome Chr8 chr8L chr8S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.1 Version 9.1
CDS Gene model Gene model Gene model
Entrez Gene 548845
100137618
398680
mRNA RefSeq NCBI Nucleotide NCBI Nucleotide
Protein RefSeq Swiss-Prot  More.. RefSeq Swiss-Prot  More.. RefSeq Swiss-Prot  More..
Genomic
 X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics X. tropicalis X. laevis.L X. laevis.S
Embryonic Protein Expression Stage profile: Stage profile:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine rlim rlim.L rlim.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards RLIM OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Rlim MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Rlim Rlim Ensembl
zebrafish
ZFIN, AGR rlim ZFIN Ensembl
chicken
GEISHA RLIM Ensembl
fruit fly
worm
Publications
First Selective degradation of excess Ldb1 by Rnf12/RLIM confers proper Ldb1 expression levels and Xlim-1/Ldb1 stoichiometry in Xenopus organizer functions., Development 2003                      
Most Recent Conservatism and variability of gene expression profiles among homeologous transcription factors in Xenopus laevis., Dev Biol 2017                            
All View All Papers
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 15 terms 8 terms 9 terms
PANTHER rlim
KEGG Pathways K16271 K16271 K16271
KOG [O] FOG: Predicted E3 ubiquitin ligase
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks rlim
ORFs rlim.S ORF1
Clones Horizon Horizon Source BioScience Horizon Source BioScience
Plasmids Addgene Addgene

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info   [+] Expand list