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Summary Expression Gene Literature (49) GO Terms (36) Nucleotides (56) Proteins (29) Interactants (605) Wiki
XB-GENEPAGE-492635
Gene Symbol:
wnt8b

Gene Name:
Wnt family member 8B

Synonyms:
Xwnt-8b , xwnt8b , wnt-8b ( Add synonyms , Nomenclature history )

Gene Function:
secreted growth factor/developmental regulator

Protein Function :
Ligand for members of the frizzled family of seven transmembrane receptors. Plays a role in the initiation of dorsal axis development. May activate a Nieuwkoop center-like signaling pathway.


InterPro :
Protein Wnt-8A/8C , Wnt CS , Wnt8 , Wnt [+]

Interactants:
Loading ...

Diseases: 


External Links:
 
Xenbase Gene ID XB-GENE-492636 XB-GENE-17333070 XB-GENE-866182
Gene Symbol wnt8b wnt8b.L wnt8b.S
Chromosome Chr7 chr7L chr7S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.1 Version 9.1
CDS Gene model Gene model
Entrez Gene 100496786
399098
mRNA NCBI Nucleotide NCBI Nucleotide
Protein NCBI Protein NCBI Protein  More.. RefSeq Swiss-Prot  More..
Genomic
 X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine wnt8b wnt8b.L wnt8b.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards WNT8B OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Wnt8b MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Wnt8b Ensembl
zebrafish
ZFIN, AGR wnt8b ZFIN Ensembl
chicken
GEISHA WNT8B Ensembl
fruit fly
worm
Publications
First Cloning and developmental expression in Xenopus laevis of seven additional members of the Wnt family., Oncogene 1992  
Most Recent Barhl2 maintains T cell factors as repressors and thereby switches off the Wnt/β-Catenin response driving Spemann organizer formation., Development 2019                                              
All View All Papers 8 paper(s) referencing morpholinos 1 paper(s) referencing Disease Ontology
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 33 terms 0 term 7 terms
PANTHER wnt8b
KEGG Pathways K00507 [+] K00714
KOG [T] Wnt family of developmental regulators
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks wnt8b
Clones Horizon Source BioScience Horizon Source BioScience
Plasmids Addgene Addgene

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