Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Summary Expression Gene Literature (154) GO Terms (5) Nucleotides (81) Proteins (21) Interactants (782) Wiki
XB-GENEPAGE- 492664

Gene Symbol: rax

Gene Name: retina and anterior neural fold homeobox

Synonyms: rx1 , Xrx1 , Xrax , Rx2A , rx , rx1a , rax-a , rax1 , Xrx1A , rax-b , rx-1
Add Xenopus synonyms , Nomenclature history


Gene Function: homeodomain transcription factor

Protein Function:
Plays a critical role in eye formation by regulating the initial specification of retinal cells and/or their subsequent proliferation.


Interactants: YYY

OMIM Disease Associations: MICROPHTHALMIA, ISOLATED 3; MCOP3
1/2
 
Xenbase Gene ID XB-GENE-492665 XB-GENE-866185 XB-GENE-6252134
Gene Symbol rax rax.L rax.S
Chromosome scaffold_1 chr1L chr1S
Molecules tropicalis laevis.L laevis.S
Gene GBrowse 7.1 JBrowse 7.1 GBrowse 4.1 JGI Genome 4.1 Ensembl 4.1 GBrowse 9.1 JBrowse 9.1 GBrowse 7.2 JBrowse 7.2 GBrowse 6.0 GBrowse 9.1 JBrowse 9.1 GBrowse 7.2 JBrowse 7.2 GBrowse 6.0
Entrez Gene
Entrez Gene
Entrez Gene
mRNA NCBI Nucleotide Refseq Refseq
Protein NCBI Protein Refseq Swiss-Prot TrEMBL Refseq Swiss-Prot
Genomic tropicalis laevis.L laevis.S
Genome Browser
GBrowse
tropicalis genome v7.1 gene model
GBrowse
laevis genome v9.1 gene model
GBrowse
laevis genome v9.1 gene model
Links
Genomic Synteny Genomicus   Metazome
Expression tropicalis laevis.L laevis.S
Ensembl Ensembl
UniGene Str.53135 Xl.187 Xl.186 [+]
RNA-Seq profile Stage profile: Stage profile:       Tissue heatmap:
Images 172 expression image(s) for tropicalis and laevis
Data Mining tropicalis laevis.L laevis.S
XenMine rax rax.L rax.S
Phenotype tropicalis laevis.L laevis.S
Smith Morpholino Screen    
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM:Gene, HGNC, GeneCards RAX OMIM, MalaCards, KEGG Disease, DECIPHER Ensembl, Protein Atlas, Allen Brain Atlas
mouse
MGI Rax MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
zebrafish
ZFIN rx1 ZFIN Ensembl
chicken
GEISHA RAX2 Ensembl
fruit fly
worm
WORMBASE
Publications
First: Coordinated regulation of and transcriptional activation by Xenopus thyroid hormone and retinoid X receptors. [J Biol Chem 1995]
Most recent: Upregulation of matrix metalloproteinase triggers transdifferentiation of retinal pigmented epithelial cells in Xenopus laevis: A Link between inflammatory response and regeneration. [Dev Neurobiol 2017]
View All Papers 52 paper(s) referencing morpholinos
Functional Ontologies tropicalis laevis.L laevis.S
GO 0 term 5 terms 5 terms
EC
PANTHER rax
KEGG Pathways K09332 K09332
KOG [R] Transcription factor, contains HOX domain
Reagents tropicalis laevis.L laevis.S
CRISPR / TALEN CRISPR tools CRISPR tools CRISPR tools
Clones
GE Dharmacon GE Dharmacon GE Dharmacon
Source BioScience Source BioScience Source BioScience
Morpholino rax MO1 , rax MO2 rax MO1 , rax MO2 rax MO1 , rax MO2
ORF rax ORF1
Affymetrix 1.0 Str.40533.1.S1_at [+] Xl.187.1.S1_at Xl.186.1.S2_at [+]
Affymetrix 2.0 Xl2.187.1.S1_at Xl2.186.1.S1_at [+]

Symbol legend[+]

My Xenbase: [ Log-in / Register ]
version: [4.5.0]

Major funding for Xenbase is provided by the National Institute of Child Health and Human Development, grant P41 HD064556