Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Summary Expression Gene Literature (191) GO Terms (9) Nucleotides (106) Proteins (38) Interactants (1419) Wiki
XB-GENEPAGE-492664
Gene Symbol:
rax

Gene Name:
retina and anterior neural fold homeobox

Synonyms:
rx1 , Xrx1 , Xrax , Rx2A , rx , rx1a , rax-a , rax1 , Xrx1A , rax-b , rx-1 ( Add synonyms , Nomenclature history )

Gene Function:
homeodomain transcription factor

Protein Function :
Plays a critical role in eye formation by regulating the initial specification of retinal cells and/or their subsequent proliferation.


Antibodies: :
RAX AB1

InterPro :
OAR dom , Homeobox CS , Homeobox dom , Homeobox-like sf [+]

Interactants:
Loading ...

Diseases: 


Disease Ontology:
isolated microphthalmia 3 [+]

OMIM:
MICROPHTHALMIA, ISOLATED 3; MCOP3

External Links:
1/2
 
Xenbase Gene ID XB-GENE-492665 XB-GENE-866185 XB-GENE-6252134
Gene Symbol rax rax.L rax.S
Chromosome Chr1 chr1L chr1S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.1 Version 9.1
CDS Gene model Gene model Gene model
Entrez Gene 100038124
397999
397998
mRNA NCBI Nucleotide NCBI Nucleotide NCBI Nucleotide
Protein NCBI Protein RefSeq Swiss-Prot  More.. RefSeq Swiss-Prot  More..
Genomic
 X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine rax rax.L rax.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC, AGR, Monarch, OMIM, GeneCards RAX OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Rax MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Rax Ensembl
zebrafish
ZFIN, AGR rx1 ZFIN Ensembl
chicken
GEISHA RAX2 Ensembl
fruit fly
Publications
First Coordinated regulation of and transcriptional activation by Xenopus thyroid hormone and retinoid X receptors., J Biol Chem 1995  
Most Recent Retinol binding protein 1 affects Xenopus anterior neural development via all-trans retinoic acid signaling., Dev Dyn 2021  
All View All Papers 56 paper(s) referencing morpholinos 6 paper(s) referencing OMIMs 12 paper(s) referencing Disease Ontology
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 9 terms 7 terms 7 terms
PANTHER rax
KEGG Pathways K09332 K09332 K09332
KOG [R] Transcription factor, contains HOX domain
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks rax
Mutants Xtr.raxmGrngr
Antibodies RAX AB1 RAX AB1 RAX AB1
Morpholinos rax MO1 , rax MO2 , rax MO3 rax MO1 , rax MO2 , rax MO3 rax MO1 , rax MO2 , rax MO3
ORFs rax.L ORF1
Clones Horizon Source BioScience Horizon Source BioScience Horizon Source BioScience
Plasmids Addgene Addgene

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info