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XB-GENEPAGE-
492780
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Gene Symbol: cirbp
Gene Name: cold inducible RNA binding protein Synonyms: Xcirp , cirp , cirbp-a , cirp1 , cirbp-b , cirbp2 , xCIRP2 , CIRP2 Add Xenopus synonyms , Nomenclature history Gene Function: cytoplasmic RNA-binding protein Protein Function  :
Cold-inducible mRNA binding protein. Acts cooperatively with elavl1/elrA to stabilize AU-rich element (ARE)-containing mRNAs by binding to them and inhibiting their deadenylation. Essential for embryon...[+]
Interactants: Loading ... 
Disease Ontology: OMIM Diseases: |
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| Xenbase Gene ID | XB-GENE-492781 | XB-GENE-6256647 | XB-GENE-492785 | ||||
| Gene Symbol | cirbp | cirbp.L | cirbp.S | ||||
| Chromosome | Chr01 | chr1L | chr1S | ||||
| Molecules | tropicalis | laevis.L | laevis.S | ||||
| Gene |
Genomic sequence
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Genomic sequence
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Genomic sequence
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| CDS |
Gene model
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Entrez Gene
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Entrez Gene
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Entrez Gene
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| mRNA |
Refseq
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Refseq
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Refseq
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| Protein
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Refseq
Swiss-Prot
TrEMBL
TrEMBL
TrEMBL
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Refseq
Swiss-Prot
TrEMBL
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Refseq
Swiss-Prot
TrEMBL
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| Genomic | tropicalis | laevis.L | laevis.S | ||||
| Genome Browser |
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| Links |
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| Genomic Synteny | Genomicus PANTHER | ||||||
| Expression | tropicalis | laevis.L | laevis.S | ||||
| Ensembl | Ensembl | ||||||
| UniGene | Str.47654 Str.26251 [+] | Xl.4515 | Xl.8151 [+] | ||||
| RNA-Seq profile | Stage profile: |
Stage profile:
Tissue heatmap:
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| Experimental regulation |
Regulation heatmap:
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| Images | 18 expression image(s) for tropicalis and laevis | ||||||
| Data Mining | tropicalis | laevis.L | laevis.S | ||||
| XenMine | cirbp | cirbp.L | cirbp.S | ||||
| Phenotype | tropicalis | laevis.L | laevis.S | ||||
| Smith Morpholino Screen | |||||||
| Orthology |
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| mouse |
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| zebrafish |
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| fruit fly |
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| worm |
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| Publications | |||||||
| First: |
XCIRP (Xenopus homolog of cold-inducible RNA-binding protein) is expressed transiently in developing pronephros and neural tissue. [Gene 1998]
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| Most recent: | Asymmetric distribution of biomolecules of maternal origin in the Xenopus laevis egg and their impact on the developmental plan. [Sci Rep 2018] | ||||||
| View All Papers 3 paper(s) referencing morpholinos | |||||||
| Functional Ontologies | tropicalis | laevis.L | laevis.S | ||||
| GO | 18 terms | 24 terms | 18 terms | ||||
| PANTHER | cirbp | ||||||
| KEGG Pathways | K13195 | K13195 | K13195 | ||||
| KOG |
[A] Alternative splicing factor SRp20/9G8 (RRM superfamily)
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| Reagents | tropicalis | laevis.L | laevis.S | ||||
| CRISPR / TALEN | CRISPR tools | CRISPR tools | CRISPR tools | ||||
| Clones | |||||||
| GE Dharmacon | GE Dharmacon | GE Dharmacon | |||||
| Source BioScience | Source BioScience | Source BioScience | |||||
| Antibody | Cirbp Ab1 | Cirbp Ab1 | Cirbp Ab1 | ||||
| Morpholino | cirbp MO1 , cirbp MO2 , cirbp MO3 | cirbp MO1 , cirbp MO2 , cirbp MO3 | cirbp MO1 , cirbp MO2 , cirbp MO3 | ||||
| ORF | cirbp.L ORF1 | cirbp.S ORF1 | |||||
| Affymetrix 1.0 | Str.8239.1.S1_x_at [+] | Xl.4515.1.S2_a_at [+] | Xl.9689.2.A1_at | ||||
| Affymetrix 2.0 | Xl2.4515.1.S1_at | Xl2.8151.1.S1_x_at [+] | |||||
Symbol legend[+]
