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Summary Expression Gene Literature (20) GO Terms (24) Nucleotides (14255) Proteins (33) Interactants (616) Wiki
XB-GENEPAGE- 492780

Gene Symbol: cirbp

Gene Name: cold inducible RNA binding protein

Synonyms: Xcirp , cirp , cirbp-a , cirp1 , cirbp-b , cirbp2 , xCIRP2 , CIRP2
Add Xenopus synonyms , Nomenclature history

Gene Function: cytoplasmic RNA-binding protein

Protein Function :
Cold-inducible mRNA binding protein. Acts cooperatively with elavl1/elrA to stabilize AU-rich element (ARE)-containing mRNAs by binding to them and inhibiting their deadenylation. Essential for embryon...[+]


Interactants: Loading ...

Disease Ontology Associations:

OMIM Disease Associations: COLD-INDUCIBLE RNA-BINDING PROTEIN; CIRBP
 
Xenbase Gene ID XB-GENE-492781 XB-GENE-6256647 XB-GENE-492785
Gene Symbol cirbp cirbp.L cirbp.S
Chromosome Chr01 chr1L chr1S
Molecules tropicalis laevis.L laevis.S
Gene Genomic sequence Genomic sequence Genomic sequence
CDS Gene model
Entrez Gene
Entrez Gene
Entrez Gene
mRNA Refseq Refseq Refseq
Protein Refseq Swiss-Prot TrEMBL TrEMBL TrEMBL Refseq Swiss-Prot TrEMBL Refseq Swiss-Prot TrEMBL
Genomic tropicalis laevis.L laevis.S
Genome Browser
Links
Genomic Synteny Genomicus
Expression tropicalis laevis.L laevis.S
Ensembl Ensembl
UniGene Str.47654 Str.26251 [+] Xl.4515 Xl.8151 [+]
RNA-Seq profile Stage profile: Stage profile:       Tissue heatmap:
Experimental regulation Regulation heatmap:
Images 18 expression image(s) for tropicalis and laevis
Data Mining tropicalis laevis.L laevis.S
XenMine cirbp cirbp.L cirbp.S
Phenotype tropicalis laevis.L laevis.S
Smith Morpholino Screen    
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM:Gene, HGNC, GeneCards CIRBP OMIM, MalaCards, KEGG Disease, DECIPHER Ensembl, Protein Atlas, Allen Brain Atlas
mouse
MGI, AGR Cirbp MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
zebrafish
ZFIN, AGR ZFIN, AGR cirbpb cirbpa ZFIN Ensembl
chicken
GEISHA CIRBP Ensembl
fruit fly
worm
WORMBASE
Publications
First: XCIRP (Xenopus homolog of cold-inducible RNA-binding protein) is expressed transiently in developing pronephros and neural tissue. [Gene 1998]
Most recent: Asymmetric distribution of biomolecules of maternal origin in the Xenopus laevis egg and their impact on the developmental plan. [Sci Rep 2018]
View All Papers 3 paper(s) referencing morpholinos
Functional Ontologies tropicalis laevis.L laevis.S
GO 18 terms 24 terms 18 terms
PANTHER cirbp
KEGG Pathways K13195 K13195 K13195
KOG [A] Alternative splicing factor SRp20/9G8 (RRM superfamily)
Reagents tropicalis laevis.L laevis.S
CRISPR / TALEN CRISPR tools CRISPR tools CRISPR tools
Clones
GE Dharmacon GE Dharmacon GE Dharmacon
Source BioScience Source BioScience Source BioScience
Antibody Cirbp Ab1 Cirbp Ab1 Cirbp Ab1
Morpholino cirbp MO1 , cirbp MO2 , cirbp MO3 cirbp MO1 , cirbp MO2 , cirbp MO3 cirbp MO1 , cirbp MO2 , cirbp MO3
ORF cirbp.L ORF1 cirbp.S ORF1
Affymetrix 1.0 Str.8239.1.S1_x_at [+] Xl.4515.1.S2_a_at [+] Xl.9689.2.A1_at
Affymetrix 2.0 Xl2.4515.1.S1_at Xl2.8151.1.S1_x_at [+]

Symbol legend[+]
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