Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Summary Expression Gene Literature (19) GO Terms (23) Nucleotides (14250) Proteins (32) Interactants (436) Wiki
XB-GENEPAGE- 492780

Gene Symbol: cirbp

Gene Name: cold inducible RNA binding protein

Synonyms: Xcirp , cirp , cirbp-a , cirp1 , cirbp-b , cirbp2 , xCIRP2 , CIRP2
Add Xenopus synonyms , Nomenclature history


Gene Function: cytoplasmic RNA-binding protein

Protein Function:
Cold-inducible mRNA binding protein. Acts cooperatively with elavl1/elrA to stabilize AU-rich sequence (ARE)-containing mRNAs by binding to them and inhibiting their deadenylation. Essential for embryo...[+]


Interactants: YYY

OMIM Disease Associations:
 
Xenbase Gene ID XB-GENE-492781 XB-GENE-6256647 XB-GENE-492785
Gene Symbol cirbp cirbp.L cirbp.S
Chromosome scaffold_1 chr1L chr1S
Molecules tropicalis laevis.L laevis.S
Gene GBrowse 7.1 JBrowse 7.1 GBrowse 4.1 JGI Genome 4.1 Ensembl 4.1 GBrowse 9.1 JBrowse 9.1 GBrowse 7.2 JBrowse 7.2 GBrowse 6.0 GBrowse 9.1 JBrowse 9.1 GBrowse 7.2 JBrowse 7.2
Entrez Gene
Entrez Gene
Entrez Gene
mRNA Refseq Refseq Refseq
Protein Refseq Swiss-Prot TrEMBL Refseq Swiss-Prot TrEMBL Refseq Swiss-Prot TrEMBL
Genomic tropicalis laevis.L laevis.S
Genome Browser
GBrowse
tropicalis genome v7.1 gene model
GBrowse
laevis genome v9.1 gene model
GBrowse
laevis genome v9.1 gene model
Links
Genomic Synteny Genomicus   Metazome
Expression tropicalis laevis.L laevis.S
Ensembl Ensembl
UniGene Str.47654 Str.26251 [+] Xl.4515 Xl.8151 [+]
RNA-Seq profile Stage profile: Stage profile:       Tissue heatmap:
Images 9 expression image(s) for tropicalis and laevis
Data Mining tropicalis laevis.L laevis.S
XenMine cirbp cirbp.L cirbp.S
Phenotype tropicalis laevis.L laevis.S
Smith Morpholino Screen    
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM:Gene, HGNC, GeneCards CIRBP OMIM, MalaCards, KEGG Disease, DECIPHER Ensembl, Protein Atlas, Allen Brain Atlas
mouse
MGI Cirbp MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
zebrafish
ZFIN ZFIN cirbpb cirbpa ZFIN Ensembl
chicken
GEISHA CIRBP Ensembl
fruit fly
worm
WORMBASE
Publications
First: XCIRP (Xenopus homolog of cold-inducible RNA-binding protein) is expressed transiently in developing pronephros and neural tissue. [Gene 1998]
Most recent: A Tissue-Mapped Axolotl De Novo Transcriptome Enables Identification of Limb Regeneration Factors. [Cell Rep 2017]
View All Papers 3 paper(s) referencing morpholinos
Functional Ontologies tropicalis laevis.L laevis.S
GO 16 terms 23 terms 17 terms
EC
PANTHER cirbp
KEGG Pathways K13195 K13195 K13195
KOG [A] Alternative splicing factor SRp20/9G8 (RRM superfamily)
Reagents tropicalis laevis.L laevis.S
CRISPR / TALEN CRISPR tools CRISPR tools CRISPR tools
Clones
GE Dharmacon GE Dharmacon GE Dharmacon
Source BioScience Source BioScience Source BioScience
Antibody Cirbp Ab1 Cirbp Ab1 Cirbp Ab1
Morpholino cirbp MO1 , cirbp MO2 , cirbp MO3 cirbp MO1 , cirbp MO2 , cirbp MO3 cirbp MO1 , cirbp MO2 , cirbp MO3
ORF cirbp ORF2 cirbp ORF1
Affymetrix 1.0 Str.8239.1.S1_x_at [+] Xl.4515.1.S2_a_at [+] Xl.9689.2.A1_at
Affymetrix 2.0 Xl2.4515.1.S1_at Xl2.8151.1.S1_x_at [+]

Symbol legend[+]

My Xenbase: [ Log-in / Register ]
version: [4.5.0]

Major funding for Xenbase is provided by the National Institute of Child Health and Human Development, grant P41 HD064556