Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Summary Expression Gene Literature (25) GO Terms (14) Nucleotides (99) Proteins (47) Interactants (168) Wiki
XB-GENEPAGE-492922
Gene Symbol:
vax2

Gene Name:
ventral anterior homeobox 2

Synonyms:
xvax2 , vax3 , dres93 , vax2-a , vax2-b ( Add synonyms , Nomenclature history )

Gene Function:
homeodomain transcription factor

Protein Function :
Transcription factor that may function in dorsoventral specification of the forebrain. Regulates the expression of Wnt signaling antagonists.


InterPro :
Homeobox metazoa , HTH motif , Homeobox dom , Homeobox CS [+]

Interactants:
Loading ...

Diseases: 


External Links:
1/2
 
Xenbase Gene ID XB-GENE-492923 XB-GENE-492927 XB-GENE-6464314
Gene Symbol vax2 vax2.L vax2.S
Chromosome Chr1 chr1L chr1S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 9.1 Version 9.2 Version 9.2
CDS Gene model Gene model Gene model
Entrez Gene 100485836
398011
100337605
mRNA NCBI Nucleotide RefSeq RefSeq
Protein NCBI Protein TrEMBL RefSeq Swiss-Prot  More.. RefSeq Swiss-Prot  More..
Genomic
 X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine vax2 vax2.L vax2.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards VAX2 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Vax2 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Vax2 Ensembl
zebrafish
ZFIN, AGR vax2 ZFIN Ensembl
chicken
fruit fly
worm
Publications
First Expression of the Vax family homeobox genes suggests multiple roles in eye development., Genes Cells 1999  
Most Recent Nosip functions during vertebrate eye and cranial cartilage development., Dev Dyn 2018                  
All View All Papers 1 paper(s) referencing morpholinos 1 paper(s) referencing OMIMs 4 paper(s) referencing Disease Ontology
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 12 terms 11 terms 9 terms
PANTHER vax2
KEGG Pathways K09318 [+] K09318 K09318
KOG [K] Transcription factor EMX1 and related HOX domain proteins
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks vax2
Antibodies Vax2 Ab1 Vax2 Ab1 Vax2 Ab1
Clones Horizon Source BioScience Horizon Source BioScience Horizon Source BioScience
Plasmids Addgene Addgene

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info   [+] Expand list
Xenbase: The Xenopus Model Organism Knowledgebase.
Version: 4.15.0
Major funding for Xenbase is provided by grant P41 HD064556