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Summary Expression Gene Literature (5) GO Terms (5) Nucleotides (201) Proteins (20) Interactants (113) Wiki
XB-GENEPAGE- 493205

Gene Symbol: tsku

Gene Name: tsukushi, small leucine rich proteoglycan

Synonyms: lrrc54 , tsukushi , X-TSK , tsk , e2ig4 , x-tsk-b1 , tsukushin , tsku-a , tsku-b
Add Xenopus synonyms , Nomenclature history


Gene Function: modulator of nodal, fgf, and bmp signaling

Protein Function:
Dorsalizing factor. Function as an inhibitor of bone morphogenetic proteins (BMP) during gastrulation.


Interactants: Loading ...

OMIM Disease Associations:
 
Xenbase Gene ID XB-GENE-493206 XB-GENE-866233 XB-GENE-6251980
Gene Symbol tsku tsku.L tsku.S
Chromosome scaffold_2 chr2L chr2S
Molecules tropicalis laevis.L laevis.S
Gene GBrowse 7.1 JBrowse 7.1 GBrowse 4.1 JGI Genome 4.1 Ensembl 4.1 GBrowse 9.1 JBrowse 9.1 GBrowse 7.2 JBrowse 7.2 GBrowse 6.0 GBrowse 9.1 JBrowse 9.1 GBrowse 7.2 JBrowse 7.2 GBrowse 6.0
Entrez Gene
Entrez Gene
Entrez Gene
mRNA Refseq Refseq Refseq
Protein Refseq Swiss-Prot Refseq TrEMBL Refseq TrEMBL
Genomic tropicalis laevis.L laevis.S
Genome Browser
Links
Genomic Synteny Genomicus   Metazome
Expression tropicalis laevis.L laevis.S
Ensembl Ensembl
UniGene Str.20457 Xl.3858 Xl.86846 [+] Xl.3858
RNA-Seq profile Stage profile: Stage profile:       Tissue heatmap:
Experimental regulation Regulation heatmap:
Images 3 expression image(s) for tropicalis and laevis
Data Mining tropicalis laevis.L laevis.S
XenMine tsku tsku.L tsku.S
Phenotype tropicalis laevis.L laevis.S
Smith Morpholino Screen    
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM:Gene, HGNC, GeneCards TSKU OMIM, MalaCards, KEGG Disease, DECIPHER Ensembl, Protein Atlas, Allen Brain Atlas
mouse
MGI Tsku MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
zebrafish
ZFIN tsku ZFIN Ensembl
chicken
GEISHA TSKU Ensembl
fruit fly
worm
WORMBASE
Publications
First: Tsukushi functions as an organizer inducer by inhibition of BMP activity in cooperation with chordin. [Dev Cell 2004]
Most recent: Sex chromosome differentiation and the W- and Z-specific loci in Xenopus laevis. [Dev Biol 2017]
View All Papers 3 paper(s) referencing morpholinos
Functional Ontologies tropicalis laevis.L laevis.S
GO 5 terms 0 term 0 term
EC
PANTHER tsku
KEGG Pathways K08130 K08130 K08130
KOG [R] FOG: Leucine rich repeat
Reagents tropicalis laevis.L laevis.S
CRISPR / TALEN CRISPR tools CRISPR tools CRISPR tools
Clones
GE Dharmacon GE Dharmacon GE Dharmacon
Source BioScience Source BioScience Source BioScience
Morpholino tsku MO1 tsku MO1 tsku MO1
ORF tsku ORF1 tsku ORF2
Affymetrix 1.0 Str.1913.1.S1_at
Affymetrix 2.0 Xl2.3858.1.S1_at [+] Xl2.10799.1.S1_at

Symbol legend[+]

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