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XB-GENEPAGE-
493205
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Gene Symbol: tsku
Gene Name: tsukushi, small leucine rich proteoglycan Synonyms: lrrc54 , tsukushi , X-TSK , tsk , e2ig4 , x-tsk-b1 , tsukushin , tsku-a , tsku-b Add Xenopus synonyms , Nomenclature history Gene Function: modulator of nodal, fgf, and bmp signaling Protein Function  :
Dorsalizing factor. Function as an inhibitor of bone morphogenetic proteins (BMP) during gastrulation.
Interactants: Loading ... 
OMIM Disease Associations: |
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| Xenbase Gene ID | XB-GENE-493206 | XB-GENE-866233 | XB-GENE-6251980 | ||||||||||
| Gene Symbol | tsku | tsku.L | tsku.S | ||||||||||
| Chromosome | Chr02 | chr2L | chr2S | ||||||||||
| Molecules | tropicalis | laevis.L | laevis.S | ||||||||||
| Gene |
Genomic sequence
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Genomic sequence
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Genomic sequence
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| CDS |
Gene model
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Entrez Gene
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Entrez Gene
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Entrez Gene
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| mRNA |
Refseq
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Refseq
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Refseq
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| Protein
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Refseq
Swiss-Prot
TrEMBL
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Refseq
TrEMBL
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Refseq
TrEMBL
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| Genomic | tropicalis | laevis.L | laevis.S | ||||||||||
| Genome Browser |
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| Links |
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| Genomic Synteny | Genomicus | ||||||||||||
| Expression | tropicalis | laevis.L | laevis.S | ||||||||||
| Ensembl | Ensembl | ||||||||||||
| UniGene | Str.20457 | Xl.3858 Xl.86846 [+] | Xl.3858 | ||||||||||
| RNA-Seq profile | Stage profile: |
Stage profile:
Tissue heatmap:
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| Experimental regulation |
Regulation heatmap:
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| Images | 3 expression image(s) for tropicalis and laevis | ||||||||||||
| Data Mining | tropicalis | laevis.L | laevis.S | ||||||||||
| XenMine | tsku | tsku.L | tsku.S | ||||||||||
| Phenotype | tropicalis | laevis.L | laevis.S | ||||||||||
| Smith Morpholino Screen | |||||||||||||
| Orthology |
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| Publications | |||||||||||||
| First: |
Tsukushi functions as an organizer inducer by inhibition of BMP activity in cooperation with chordin. [Dev Cell 2004]
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| Most recent: |
Tsukushi modulates Xnr2, FGF and BMP signaling: regulation of Xenopus germ layer formation. [PLoS One 2007]
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| View All Papers 3 paper(s) referencing morpholinos | |||||||||||||
| Functional Ontologies | tropicalis | laevis.L | laevis.S | ||||||||||
| GO | 5 terms | 0 term | 0 term | ||||||||||
| PANTHER | tsku | ||||||||||||
| KEGG Pathways | K08130 | K08130 | K08130 | ||||||||||
| KOG |
[R] FOG: Leucine rich repeat
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| Reagents | tropicalis | laevis.L | laevis.S | ||||||||||
| CRISPR / TALEN | CRISPR tools | CRISPR tools | CRISPR tools | ||||||||||
| Clones | |||||||||||||
| GE Dharmacon | GE Dharmacon | GE Dharmacon | |||||||||||
| Source BioScience | Source BioScience | Source BioScience | |||||||||||
| Morpholino | tsku MO1 | tsku MO1 | tsku MO1 | ||||||||||
| ORF | tsku ORF1 | tsku ORF2 | |||||||||||
| Affymetrix 1.0 | Str.1913.1.S1_at | ||||||||||||
| Affymetrix 2.0 | Xl2.3858.1.S1_at [+] | Xl2.10799.1.S1_at | |||||||||||
Symbol legend[+]
