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Summary Expression Gene Literature (4) GO Terms (4) Nucleotides (224) Proteins (34) Interactants (61) Wiki
XB-GENEPAGE-493205
Gene Symbol:
tsku

Gene Name:
tsukushi, small leucine rich proteoglycan

Synonyms:
lrrc54 , tsukushi , X-TSK , tsk , e2ig4 , x-tsk-b1 , tsukushin , tsku-a , tsku-b ( Add synonyms , Nomenclature history )

Gene Function:
modulator of nodal, fgf, and bmp signaling

Protein Function :
Dorsalizing factor. Functions as an inhibitor of bone morphogenetic proteins (BMP) during gastrulation.



Interactants:
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Diseases: 


External Links:
 
Xenbase Gene ID XB-GENE-493206 XB-GENE-866233 XB-GENE-6251980
Gene Symbol tsku tsku.L tsku.S
Chromosome Chr2 chr2L chr2S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.1 Version 9.1
CDS Gene model Gene model Gene model
Entrez Gene 496792
496379
496404
mRNA RefSeq NCBI Nucleotide NCBI Nucleotide
Protein RefSeq Swiss-Prot  More.. NCBI Protein RefSeq  More.. NCBI Protein RefSeq  More..
Genomic
X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics X. tropicalis X. laevis.L X. laevis.S
Embryonic Protein Expression Stage profile: Stage profile:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine tsku tsku.L tsku.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards TSKU OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Tsku MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Tsku Ensembl
zebrafish
ZFIN, AGR tsku ZFIN Ensembl
chicken
GEISHA TSKU Ensembl
fruit fly
worm
Publications
First Tsukushi functions as an organizer inducer by inhibition of BMP activity in cooperation with chordin., Dev Cell 2004          
Most Recent Tsukushi modulates Xnr2, FGF and BMP signaling: regulation of Xenopus germ layer formation., PLoS One 2007                      
All View All Papers 3 paper(s) referencing morpholinos
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 4 terms 0 term 0 term
PANTHER tsku
KEGG Pathways K08130 K08130 K08130
KOG [R] FOG: Leucine rich repeat
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks tsku
Morpholinos (on-target & off-target) tsku MO1 tsku MO1
ORFs tsku ORF1 tsku.L ORF1 tsku.S ORF1
Clones Horizon Source BioScience Horizon Source BioScience Horizon Source BioScience
Plasmids Addgene Addgene

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