Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Summary Expression Gene Literature (8) GO Terms (19) Nucleotides (153) Proteins (26) Interactants (194) Wiki
XB-GENEPAGE-493390

Gene Symbol: smarcal1

Gene Name: SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1

Synonyms: harp ( Add Xenopus synonyms , Nomenclature history )

Gene Function: chromatin remodeling protein

Protein Function :
ATP-dependent annealing helicase that catalyzes the rewinding of the stably unwound DNA. Rewinds single-stranded DNA bubbles that are stably bound by replication protein A (RPA). Acts throughout the ge...[+]

Interactants: Loading ...
Disease Ontology: Schimke immuno-osseous dysplasia

OMIM Diseases: SCHIMKE IMMUNOOSSEOUS DYSPLASIA; SIOD

 
Xenbase Gene ID XB-GENE-493391 XB-GENE-866253 XB-GENE-17342986
Gene Symbol smarcal1 smarcal1.L smarcal1.S
Chromosome scaffold_33 chr9_10L
Molecules tropicalis laevis.L laevis.S
Gene Genomic sequence Genomic sequence
CDS Gene model
Entrez Gene
Entrez Gene
mRNA Refseq Refseq
Protein Refseq Swiss-Prot Swiss-Prot Refseq Swiss-Prot TrEMBL Swiss-Prot
Genomic tropicalis laevis.L laevis.S
Genome Browser
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics tropicalis laevis.L laevis.S
Embryonic Protein Expression Stage profile:
Data Mining tropicalis laevis.L laevis.S
XenMine smarcal1 smarcal1.L smarcal1.S
Phenotype tropicalis laevis.L laevis.S
Smith Morpholino Screen    
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM:Gene, HGNC, GeneCards SMARCAL1 OMIM, MalaCards, KEGG Disease, DECIPHER Ensembl, Protein Atlas, Allen Brain Atlas
mouse
MGI, AGR Smarcal1 MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
zebrafish
ZFIN, AGR smarcal1 ZFIN Ensembl
chicken
GEISHA SMARCAL1 Ensembl
fruit fly
worm
WORMBASE
Publications
First The SNF2 domain protein family in higher vertebrates displays dynamic expression patterns in Xenopus laevis embryos., Gene 2004                                                
Most Recent HELLS and CDCA7 comprise a bipartite nucleosome remodeling complex defective in ICF syndrome., Proc Natl Acad Sci U S A 2018                                  
All View All Papers 1 paper(s) referencing morpholinos 8 paper(s) referencing OMIMs 8 paper(s) referencing Disease Ontology
Functional Ontologies tropicalis laevis.L laevis.S
GO 19 terms 9 terms 0 term
PANTHER smarcal1
KEGG Pathways K14440 K14440
KOG [B] Chromatin remodeling protein HARP/SMARCAL1, DEAD-box superfamily
Reagents tropicalis laevis.L laevis.S
CRISPR / TALEN CRISPR tools CRISPR tools CRISPR tools
Clones
GE Dharmacon GE Dharmacon GE Dharmacon
Morpholino smarcal1 MO1 smarcal1 MO1 smarcal1 MO1
ORF smarcal1.L ORF1
Affymetrix 1.0 Str.11392.1.S1_at [+] Xl.14457.1.A1_at [+]
Affymetrix 2.0 Xl2.6594.1.S1_at

Symbol legend: - Blast this sequence    - View this sequence       - Literature or expression images  
Xenbase: The Xenopus laevis and X. tropicalis resource.
Version: 4.11.1


Major funding for Xenbase is provided by grant P41 HD064556