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XB-GENEPAGE-
493705
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Gene Symbol: wnt8a
Gene Name: Wnt family member 8A Synonyms: Xwnt8 , Xwnt-8 , wnt-8 , wnt8 Add Xenopus synonyms , Nomenclature history Gene Function: secreted growth factor/developmental regulator Protein Function  :
Ligand for members of the frizzled family of seven transmembrane receptors. Plays a role in ventral mesodermal patterning during embryogenesis. Mimics Nieuwkoop center activity. Causes dorsal mesoderma...[+]
Interactants: Loading ... 
Disease Ontology Associations: OMIM Disease Associations: WINGLESS-TYPE MMTV INTEGRATION SITE FAMILY, MEMBER 8A; WNT8A |
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1/5 | Xenbase Gene ID | XB-GENE-493706 | XB-GENE-866281 | XB-GENE-17343348 | ||||
| Gene Symbol | wnt8a | wnt8a.L | wnt8a.S | ||||
| Chromosome | Chr03 | chr3L | chr3S | ||||
| Molecules | tropicalis | laevis.L | laevis.S | ||||
| Gene |
Genomic sequence
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Genomic sequence
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Genomic sequence
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| CDS |
Gene model
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Entrez Gene
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Entrez Gene
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| mRNA |
Refseq
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Refseq
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| Protein
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Refseq
TrEMBL
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Refseq
Swiss-Prot
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| Genomic | tropicalis | laevis.L | laevis.S | ||||
| Genome Browser |
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| Links |
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| Genomic Synteny | Genomicus | ||||||
| Expression | tropicalis | laevis.L | laevis.S | ||||
| Ensembl | Ensembl | ||||||
| UniGene | Str.15027 | Xl.49 | |||||
| RNA-Seq profile | Stage profile: |
Stage profile:
Tissue heatmap:
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| Experimental regulation |
Regulation heatmap:
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| Images | 99 expression image(s) for tropicalis and laevis | ||||||
| Data Mining | tropicalis | laevis.L | laevis.S | ||||
| XenMine | wnt8a | wnt8a.L | wnt8a.S | ||||
| Phenotype | tropicalis | laevis.L | laevis.S | ||||
| Smith Morpholino Screen | tneu118d19 | ||||||
| Orthology |
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| human |
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| mouse |
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| zebrafish |
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| chicken |
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| fruit fly |
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| worm |
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| Publications | |||||||
| First: |
Enhanced c-myc gene expression during forelimb regenerative outgrowth in the young Xenopus laevis. [Proc Natl Acad Sci U S A 1990]
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| Most recent: | Molecular modeling of the complex between the xWNT8 protein and the CRD domain of the mFZD8 receptor. [Dokl Biochem Biophys null] | ||||||
| View All Papers 107 paper(s) referencing morpholinos 8 paper(s) referencing OMIMs 13 paper(s) referencing Disease Ontologies | |||||||
| Functional Ontologies | tropicalis | laevis.L | laevis.S | ||||
| GO | 6 terms | 13 terms | 0 term | ||||
| PANTHER | wnt8a | ||||||
| KEGG Pathways | K00714 | K00714 | |||||
| KOG |
[T] Wnt family of developmental regulators
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| Reagents | tropicalis | laevis.L | laevis.S | ||||
| CRISPR / TALEN | CRISPR tools | CRISPR tools | CRISPR tools | ||||
| Clones | EXRC - 1 clone(s) | EXRC - 2 clone(s) | |||||
| GE Dharmacon | GE Dharmacon | GE Dharmacon | |||||
| Source BioScience | Source BioScience | ||||||
| Morpholino | wnt8a MO1 , wnt8a MO2 , wnt8a MO3 , wnt8a MO4 , wnt8a MO5 , wnt8a MO6 | wnt8a MO1 , wnt8a MO2 , wnt8a MO3 , wnt8a MO4 , wnt8a MO5 , wnt8a MO6 | wnt8a MO1 , wnt8a MO2 , wnt8a MO3 , wnt8a MO4 , wnt8a MO5 , wnt8a MO6 | ||||
| ORF | wnt8a.L ORF1 | ||||||
| Affymetrix 1.0 | Str.15027.1.S1_at | Xl.49.1.S1_at | |||||
| Affymetrix 2.0 | Xl2.49.1.S1_a_at | ||||||
Symbol legend[+]
