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Summary Expression Gene Literature (11) GO Terms (9) Nucleotides (310) Proteins (46) Interactants (234) Wiki
Gene Symbol:

Gene Name:
WD repeat domain 5

xwdr5 , swd3 , big-3 , wdr5-a , wdr5-b ( Add synonyms , Nomenclature history )

Gene Function:
WD40 repeat-containing protein

Protein Function :
Contributes to histone modification. May position the N-terminus of histone H3 for efficient trimethylation at 'Lys-4'. As part of the MLL1/MLL complex it is involved in methylation and dimethylation a...[+]

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External Links:
Xenbase Gene ID XB-GENE-493883 XB-GENE-6255108 XB-GENE-866297
Gene Symbol wdr5 wdr5.L wdr5.S
Chromosome scaffold_19 chr8L chr8S
Molecules tropicalis laevis.L laevis.S
Genomic Sequence Version 9.1 Version 9.2 Version 9.2
CDS Gene model Gene model Gene model
Entrez Gene 496891
mRNA RefSeq RefSeq RefSeq
Protein RefSeq Swiss-Prot RefSeq RefSeq
tropicalis laevis.L laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics tropicalis laevis.L laevis.S
Embryonic Protein Expression Stage profile: Stage profile:
Data Mining tropicalis laevis.L laevis.S
XenMine wdr5 wdr5.L wdr5.S
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
HGNC AGR, OMIM:Gene, GeneCards WDR5 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
MGI, AGR Wdr5 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
RGD, AGR Wdr5 Ensembl
ZFIN, AGR wdr5 ZFIN Ensembl
fruit fly
First WDR5 associates with histone H3 methylated at K4 and is essential for H3 K4 methylation and vertebrate development., Cell 2005    
Most Recent Mechanical strain, novel genes and evolutionary insights: news from the frog left-right organizer., Curr Opin Genet Dev 2019        
All View All Papers 2 paper(s) referencing morpholinos 1 paper(s) referencing OMIMs 2 paper(s) referencing Disease Ontology
Functional Ontologies tropicalis laevis.L laevis.S
GO 9 terms 0 term 0 term
KEGG Pathways K14963 K14963 K14963
KOG [R] WD40 repeat-containing protein
Reagents tropicalis laevis.L laevis.S
CRISPRscan Tracks wdr5
Antibodies wdr5 Ab1
Morpholinos wdr5 MO1 , wdr5 MO2 , wdr5 MO3 , wdr5 MO4 , wdr5 MO5 wdr5 MO1 , wdr5 MO2 , wdr5 MO3 , wdr5 MO4 , wdr5 MO5 wdr5 MO1 , wdr5 MO2 , wdr5 MO3 , wdr5 MO4 , wdr5 MO5
ORFs wdr5 ORF1 wdr5.S ORF1
Clones Horizon Source BioScience Horizon Source BioScience Horizon Source BioScience

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