Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Summary Expression Gene Literature (67) GO Terms (22) Nucleotides (328) Proteins (50) Interactants (587) Wiki
XB-GENEPAGE-493908
Gene Symbol:
actn1

Gene Name:
actinin alpha 1

Synonyms:
alpha actinin , actinin , a-actinin ( Add synonyms , Nomenclature history )

Gene Function:
Ca2+-binding actin-bundling protein [KOG]

Protein Function :



Interactants:
Loading ...

Diseases: 


Disease Ontology:
platelet-type bleeding disorder 15

OMIM:
BLEEDING DISORDER, PLATELET-TYPE, 15; BDPLT15

External Links:
 
Xenbase Gene ID XB-GENE-493909 XB-GENE-493913 XB-GENE-17333838
Gene Symbol actn1 actn1.L actn1.S
Chromosome Chr08 chr8L chr8S
Molecules tropicalis laevis.L laevis.S
Genomic Sequence Version 9.1 Version 9.2 Version 9.2
CDS Gene model Gene model Gene model
Entrez Gene 780123
399422
431885
mRNA RefSeq RefSeq RefSeq
Protein RefSeq RefSeq RefSeq
Genomic
tropicalis laevis.L laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics tropicalis laevis.L laevis.S
Embryonic Protein Expression Stage profile: Stage profile:
Data Mining tropicalis laevis.L laevis.S
XenMine actn1 actn1.L actn1.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards ACTN1 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Actn1 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Actn1 Ensembl
zebrafish
ZFIN, AGR actn1 ZFIN Ensembl
chicken
GEISHA ACTN1 Ensembl
fruit fly
worm
Publications
First Locomotion of Xenopus epidermis cells in primary culture., J Cell Sci 1981  
Most Recent Regulation of actin assembly by PI(4,5)P2 and other inositol phospholipids: An update on possible mechanisms., Biochem Biophys Res Commun 2018  
All View All Papers 7 paper(s) referencing morpholinos 1 paper(s) referencing Disease Ontology
Functional Ontologies tropicalis laevis.L laevis.S
GO 22 terms 22 terms 22 terms
PANTHER actn1
KEGG Pathways K05699 K05699 K05699
KOG [Z] Ca2+-binding actin-bundling protein (actinin), alpha chain (EF-Hand protein superfamily)
Reagents tropicalis laevis.L laevis.S
CRISPRscan Tracks actn1
Morpholinos actn1 MO1 actn1 MO1 actn1 MO1
ORFs actn1 ORF1 actn1.L ORF1 MGC81191 ORF1
Clones Horizon Source BioScience Horizon Source BioScience Horizon

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info   [+] Expand list
Xenbase: The Xenopus Model Organism Knowledgebase.
Version: 4.14.0
Major funding for Xenbase is provided by grant P41 HD064556