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Summary Expression Gene Literature (14) GO Terms (9) Nucleotides (178) Proteins (34) Interactants (187) Wiki
XB-GENEPAGE-493952
Gene Symbol:
itga5

Gene Name:
integrin subunit alpha 5

Synonyms:
VLA-5 , Integrin alpha5 ( Add synonyms , Nomenclature history )

Gene Function:
cell surface receptor subunit

Protein Function :
Integrin alpha-5/beta-1 (ITGA5:ITGB1) is a receptor for fibronectin. It recognizes the sequence R-G-D in its ligands. ITGA5:ITGB1 acts as a receptor for fibrillin-1 (FBN1) and mediates R-G-D-dependent ...[+]



Interactants:
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Diseases: 


External Links:
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Xenbase Gene ID XB-GENE-493953 XB-GENE-866304 XB-GENE-17340799
Gene Symbol itga5 itga5.L itga5.S
Chromosome Chr02 chr2L chr2S
Molecules tropicalis laevis.L laevis.S
Genomic Sequence Version 9.1 Version 9.2 Version 9.2
CDS Gene model Gene model Gene model
Entrez Gene 100492002
394366
397842
mRNA NCBI Nucleotide RefSeq NCBI Nucleotide
Protein NCBI Protein RefSeq Swiss-Prot NCBI Protein
Genomic
tropicalis laevis.L laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics tropicalis laevis.L laevis.S
Embryonic Protein Expression Stage profile: Stage profile:
Data Mining tropicalis laevis.L laevis.S
XenMine itga5 itga5.L itga5.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards ITGA5 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Itga5 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Itga5 Ensembl
zebrafish
ZFIN, AGR itga5 ZFIN Ensembl
chicken
GEISHA ITGA5 Ensembl
fruit fly
worm
Publications
First Fibronectin-rich fibrillar extracellular matrix controls cell migration during amphibian gastrulation., Int J Dev Biol 1990                
Most Recent LIN28B increases neural crest cell migration and leads to transformation of trunk sympathoadrenal precursors., Cell Death Differ 2020  
All View All Papers 4 paper(s) referencing morpholinos 1 paper(s) referencing OMIMs 2 paper(s) referencing Disease Ontology
Functional Ontologies tropicalis laevis.L laevis.S
GO 4 terms 7 terms 3 terms
PANTHER itga5
KEGG Pathways K06484 K06484
KOG [W] Vitronectin receptor, alpha subunit
Reagents tropicalis laevis.L laevis.S
CRISPRscan Tracks itga5
Antibodies Itgb1 Ab3 , Itgb1 Ab4 , Itga5 Ab1 , Itga5 Ab2 Itgb1 Ab3 , Itgb1 Ab4 , Itga5 Ab1 , Itga5 Ab2 Itga5 Ab2
Morpholinos itga5 MO1 itga5 MO1 itga5 MO1
Clones Horizon Horizon Source BioScience Horizon

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