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Summary Expression Gene Literature (3) GO Terms (11) Nucleotides (406) Proteins (55) Interactants (199) Wiki
XB-GENEPAGE-494338
Gene Symbol:
actn4

Gene Name:
actinin alpha 4

Synonyms:
mgc79707 , mgc80841 ( Add synonyms , Nomenclature history )

Gene Function:
Ca2+-binding actin-bundling protein [KOG]

Protein Function :


InterPro :
EF-hand Ca insen , Spectrin repeat , EF hand dom , EF-hand-dom pair [+]

Interactants:
Loading ...

Diseases: 


Disease Ontology:
focal segmental glomerulosclerosis 1

OMIM:
FOCAL SEGMENTAL GLOMERULOSCLEROSIS 1; FSGS1

External Links:
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Xenbase Gene ID XB-GENE-494339 XB-GENE-17340657 XB-GENE-494343
Gene Symbol actn4 actn4.L actn4.S
Chromosome Chr8 chr8L chr8S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.1 Version 9.1
CDS Gene model Gene model Gene model
Entrez Gene 448522
734930
446865
mRNA RefSeq NCBI Nucleotide NCBI Nucleotide
Protein NCBI Protein RefSeq  More.. NCBI Protein RefSeq  More.. NCBI Protein RefSeq  More..
Genomic
 X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics X. tropicalis X. laevis.L X. laevis.S
Embryonic Protein Expression Stage profile: Stage profile:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine actn4 actn4.L actn4.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC, AGR, Monarch, OMIM, GeneCards ACTN4 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Actn4 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Actn4 Ensembl
zebrafish
ZFIN, AGR actn4 ZFIN Ensembl
chicken
GEISHA ACTN4 Ensembl
fruit fly
Publications
First Robust identification of Ptbp1-dependent splicing events by a junction-centric approach in Xenopus laevis., Dev Biol 2017              
Most Recent Disabled-2: a positive regulator of the early differentiation of myoblasts., Cell Tissue Res 2020                                
All View All Papers
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 11 terms 2 terms 4 terms
PANTHER actn4
KEGG Pathways K05699 K05699 K05699
KOG [Z] Ca2+-binding actin-bundling protein (actinin), alpha chain (EF-Hand protein superfamily)
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks actn4
ORFs actn4 ORF1 MGC131041 ORF1 actn4.S ORF1
Clones Horizon Source BioScience Horizon Horizon
Plasmids Addgene Addgene

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