Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Summary Expression Gene Literature (18) GO Terms (23) Nucleotides (87) Proteins (38) Interactants (462) Wiki
XB-GENEPAGE-494749
Gene Symbol:
lmx1b.1

Gene Name:
LIM homeobox transcription factor 1, beta, gene 1

Synonyms:
Xlmx1b , lmx1.2 , nps1 , lmx1b ( Add synonyms , Nomenclature history )

Gene Function:
homeodomain transcription factor

Protein Function :
Required for early specification of the kidney glomus, lying upstream of wt1 in the pathway controlling glomus differentiation. The balance in levels and expression patterns of binding partners such as...[+]



Interactants:
Loading ...

Diseases: 


Disease Ontology:
open-angle glaucoma [+]

OMIM:
NAIL-PATELLA SYNDROME; NPS [+]

External Links:
 
Xenbase Gene ID XB-GENE-494750 XB-GENE-17339856 XB-GENE-494754
Gene Symbol lmx1b.1 lmx1b.1.L lmx1b.1.S
Chromosome Chr8 chr8L chr8S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.1 Version 9.1
CDS Gene model Gene model Gene model
Entrez Gene 100495130
108698243
399182
mRNA NCBI Nucleotide NCBI Nucleotide NCBI Nucleotide
Protein NCBI Protein NCBI Protein NCBI Protein NCBI Protein  More.. RefSeq Swiss-Prot  More..
Genomic
X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine lmx1b.1 lmx1b.1.L lmx1b.1.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards LMX1B OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Lmx1b MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Lmx1b Ensembl
zebrafish
ZFIN, AGR lmx1bb ZFIN Ensembl
chicken
GEISHA LMX1B Ensembl
fruit fly
worm
Publications
First An epidermal signal regulates Lmx-1 expression and dorsal-ventral pattern during Xenopus limb regeneration., Dev Biol 2001              
Most Recent Hyperinnervation improves Xenopus laevis limb regeneration., Dev Biol 2018                      
All View All Papers 4 paper(s) referencing morpholinos 1 paper(s) referencing Disease Ontology
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 19 terms 7 terms 11 terms
PANTHER lmx1b.1
KEGG Pathways K09371 K09371
KOG [R] Transcription factor, contains HOX domain
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks lmx1b.1
Morpholinos (on-target & off-target) lmx1b.1 MO4 lmx1b.1 MO3 , lmx1b.1 MO4 lmx1b.1 MO1 , lmx1b.1 MO2 , lmx1b.1 MO3 , lmx1b.1 MO4
Clones Horizon Source BioScience Horizon Horizon Source BioScience
Plasmids Addgene Addgene

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info