Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Summary Expression Gene Literature (126) GO Terms (16) Nucleotides (322) Proteins (42) Interactants (292) Wiki
XB-GENEPAGE-495081
Gene Symbol:
yes1

Gene Name:
YES proto-oncogene 1, Src family tyrosine kinase

Synonyms:
yes , c-yes ( Add synonyms , Nomenclature history )

Gene Function:
serine/threonine kinase

Protein Function :
Non-receptor protein tyrosine kinase that is involved in the regulation of cell growth and survival, apoptosis, cell-cell adhesion, cytoskeleton remodeling, differentiation, G2/M progression and cytoki...[+]


InterPro :
Kinase-like dom sf , SH2 dom sf , SH3-like dom sf , Ser-Thr/Tyr kinase cat dom [+]

Interactants:
Loading ...

Diseases: 


External Links:
 
Xenbase Gene ID XB-GENE-495082 XB-GENE-866413 XB-GENE-17338415
Gene Symbol yes1 yes1.L yes1.S
Chromosome Chr6 chr6L chr6S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.1 Version 9.1
CDS Gene model Gene model
Entrez Gene 493548
379629
mRNA RefSeq NCBI Nucleotide
Protein NCBI Protein RefSeq  More.. NCBI Protein RefSeq  More..
Genomic
 X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics X. tropicalis X. laevis.L X. laevis.S
Embryonic Protein Expression Stage profile: Stage profile:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine yes1 yes1.L yes1.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards YES1 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Yes1 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Yes1 Ensembl
zebrafish
ZFIN, AGR yes1 ZFIN Ensembl
chicken
GEISHA YES1 Ensembl
fruit fly
worm
Publications
First The yes proto-oncogene is present in amphibians and contributes to the maternal RNA pool in the oocyte., Oncogene Res 1989  
Most Recent Wbp2nl has a developmental role in establishing neural and non-neural ectodermal fates., Dev Biol 2017                      
All View All Papers 2 paper(s) referencing morpholinos
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 13 terms 6 terms 0 term
PANTHER yes1
KEGG Pathways K05705 K05705
KOG [T] Tyrosine kinases
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks yes1
ORFs yes1 ORF1 yes1.L ORF1
Clones Horizon Source BioScience Horizon Source BioScience
Plasmids Addgene Addgene

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info   [+] Expand list