Gene Symbol: bambi Gene Name: BMP and activin membrane-bound inhibitor Synonyms: mgc89501 Add Xenopus synonyms Gene Function: negative regulator of TGF-beta (pseudoreceptor) Interactants: bmp4(10) , tgfb1(9) , chrd(7) , nog(5) , smad7(4) , t(4) , ventx2.2(4) View All	1/2

Molecules		tropicalis	laevis
Gene		JGI XT Genome 7.1 JGI XT Genome 4.1 Ensembl 4.1	JGI XL Genome 6.0
		Entrez Gene	Entrez Gene
mRNA		Refseq >NM_001008193|Xenopus (Silurana) tropicalis BMP and activin membrane-bound inhibitor (bambi), mRNA CGCAGGGATTACAATAGCCGCTGCCGCTGTCCGTGTTGCTTTACTGTGGATTTTGGGAAGCTGATCCCGCAGAGCAGGGGTTATTCCCCACCGAGAGCCATTCCTCGCCCACTAGCGAAGGGTTCGGCGCTTCTTCCCTGGGCTCTGGATGCTAAAGCTGGGCTGGATGGTGGGATCTCTCTGGCGCTGAAGACGTGCAAGCCTGCCCGCAGGGACCTTTAAATGGATCGCCAAGCCAGCCTGATATCTCTCTGGCTTCAGTTAGAGCTGTGTGCCATGGCCATCCTACTAACCAAGGGGGAAATCAGATGCTACTGTGACGCTCCACACTGTGTTGCGACTGGCTACATGTGCAAGTCGGAGCTGAATGCCTGCTTCTCAAGGCTCCTTAACCCCCAGAACACAAACTCTCCTCTCACCCACGGCTGCTTGGACTCCCTGACCAGCACCACGGAGCTGTGCAAGGCAAACACCGAGCAGAATCACACAGGTGCGCCGGCGCTGAGGTTGGAGTGCTGTCACGAAGATATGTGCAATTACAGAGGTCTGCACGATGTTCTGTCTCATCCCAGGAGTGATACATCAGGTACAGGAGGCAGACACCAACATGACAACACAAGGAACCTCATCACGAAGGTCCACGAATTGACCTCATCCAAAGAACTGTGGTTCAGGGCAGCTGTCATAGCCGTGCCCATAGCTGGGGGACTGATCCTGGTGCTCCTCATAATGCTTGCACTTCGAATGCTGCGCAGCGAAAACAAAAGACTAAAAGATCAGAGACAACAGATGCTGTCACGGCTTCACTACAGCTTTCACGGCCACCATTCAAAAAAGGGCCAGATGGCCAAATTAGACTTGGAGTGCATGGTGCCAGTGACTGGTCACGAAAACTGCTGCCTGACCTGTGACAAACTGAGGCACACGGACCTTAGCAATGACAAAATCATCTCATTGGTCCATTGGGGGATGTACAGCGGACACGGCAAGCTGGAATTTGTATGACCGCCTTCCTGAGACAATGGTCCAGTAGGGGGCCTTTTGGATCCTGCTGGATGGGAGCACTTTATCTTTATTTTTAAACAAAAATGAACTGATCCTTAGGTGGACAAAATTGGGATCTTTGCACAGCAAATATTTAATGTTTCCTGTGTGGGGTCCAAAAATGTCATATTTGCACAGAAAGAGCAACGGACTCTCTTTTATTTGCTTAACATTGAAAAATGTAGAAGCTGTACACACTGTCACAATGTGTTTTTTTTTTTGAGTTTTAGGGAGCTAATATTGTTATTGAAATAAACTGTACACAATGTACAAATTCCTATATATGTTTATTGTATAGAAGGTTATTTTTTTTTTTTTTTTAAATATATATTTTTGTCTGGAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA	Refseq >NM_001087664|Xenopus laevis BMP and activin membrane-bound inhibitor (bambi), mRNA ATCGAATTCCCCGGGGCGACTCCGAGGGATTACAATAGCTACAGCTGTCTCTATTGCTTTACCGTGGACTTTAGGAAGCTGATCCGACTGGACAGGGATTATTCCCCACACAGGGCGACTCCGTGCCCCCCGCTTCTTTCCTCGGGATCTGGATGGTGACGCTGGGCTGGATGGTGGAATCTCTCCGGCGCTGAAGACTTGCAGACCTGCCCGCGGGGACCTTTAAATGGATCGCCAATCCAGTCTGATCTCCCTGTGGCTTCAGTTAGAGCTGTGCGCCATGGCCGTGCTGCTGACTAAAGGGGAAATCCGATGCTACTGTGACGCCCCGCAGTGTGTTGCAACTGGCTACATGTGCAAGTCGGAGCTCAACGCCTGCTTTACTAAGCTCCTGTACCCCCAGAACACAAACTCTCCTCTCACCCACGGGTGCCTGGACTCCCTGGGCAGCACCACAGAGCCGTGCAAGGGCAGCGCAGGGCAGAATCCCACAGCAGCGCCGACGCTCAGGTTGGAGTGCTGTCATGAAGATATGTGCAATTACAGAGGTCTGCACGATGTTCTGTCTCATCCCAGGAGTGATGCATCAGGTCCAGGGGGCAGACACCAACACGACAACACAAGGAACCTCATCACGAAGGTCCACGAGTTGACCTCATCCAAAGAACTGTGGTTCAGGGCAGCTGTCATAGCCGTGCCCATAGCTGGTGGACTGATCCTGGTGCTCCTCATAATGCTTGCACTTCGGATGCTGCGTAGCGAAAACAAAAGACTAAAAGATCAGAGGCAACAGATGCTGTCGCGGCTTCACTACAGCTTTCACGGGCACCATTCAAAAAAGGGCCAGATGGCCAAACTAGACTTGGAGTGTATGGTGCCAGTGACTGGTCACGAAAACTGCTGCCTGACCTGTGACAAACTGAGGCACACGGACCTTAGCAATGACAAAATCATCTCATTGGTCCATTGGGGGATGTACAGCGGACATGGCAAACTGGAATTTGTATGACCGCCTTCCCGGCACAATGGTCCAGTAGGGGGTCTTCTGGATCCTGCTGGATGGGAGCACTTTATCTTTCTTTCCTTTTAAACAAAACAAACTGATCTTTAGGAGGACGAAAAATTTGGGATCTTTGCACAGCAAATATTTAATGTTTCCTGTGTGGGGTCCAAAAAATGTCATATTTGCACAGAAAGAGCGATGGACTCTGTTTTTATTTGCTTAACATTGAAAAATGTGGAAGCTGTACACACTGTCACAATGTGTTTTTGTTTTGTTTTTTTGAGTTTTAGGGAGCTAATATTGTTATTGAAATAAACTGTACACAATGTACAAGTTCCTATATACAGTATGTTTATTGTATAGAAGCTGTTTTTTTTTTTTTTTTAAATATATATTTTTGTCTGGAACATTAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
Protein		Refseq >NP_001008194|BMP and activin membrane-bound inhibitor precursor [Xenopus (Silurana) tropicalis] MDRQASLISLWLQLELCAMAILLTKGEIRCYCDAPHCVATGYMCKSELNACFSRLLNPQNTNSPLTHGCLDSLTSTTELCKANTEQNHTGAPALRLECCHEDMCNYRGLHDVLSHPRSDTSGTGGRHQHDNTRNLITKVHELTSSKELWFRAAVIAVPIAGGLILVLLIMLALRMLRSENKRLKDQRQQMLSRLHYSFHGHHSKKGQMAKLDLECMVPVTGHENCCLTCDKLRHTDLSNDKIISLVHWGMYSGHGKLEFV	Refseq >NP_001081133|BMP and activin membrane-bound inhibitor precursor [Xenopus laevis] MDRQSSLISLWLQLELCAMAVLLTKGEIRCYCDAPQCVATGYMCKSELNACFTKLLYPQNTNSPLTHGCLDSLGSTTEPCKGSAGQNPTAAPTLRLECCHEDMCNYRGLHDVLSHPRSDASGPGGRHQHDNTRNLITKVHELTSSKELWFRAAVIAVPIAGGLILVLLIMLALRMLRSENKRLKDQRQQMLSRLHYSFHGHHSKKGQMAKLDLECMVPVTGHENCCLTCDKLRHTDLSNDKIISLVHWGMYSGHGKLEFV

Genomic		tropicalis
Genome Browser		Xenbase	Xenbase JGI Ensembl UCSC		Xenbase
Synteny		Metazome

Expression		tropicalis	laevis
UniGene		Str.6638 [+] Str.46794	Xl.4715
Unigene EST Profile		EST Profile	EST Profile
GEO data			GEO
Images		11 expression image(s) for tropicalis and laevis

Orthology		MOD	Entrez Gene	Genetic Phenotypes	Morphants
human		OMIM:Gene, HGNC	BAMBI
mouse		MGI	Bambi	All(4) Targeted, knock Out(3) Targeted, other(1)
zebrafish		ZFIN ZFIN	bambia bambib

Publications
First:		Silencing of TGF-beta signalling by the pseudoreceptor BAMBI. [Nature 1999]
Most recent:		fus/TLS orchestrates splicing of developmental regulators during gastrulation. [Genes Dev 2012]
		View All Papers 5 paper(s) referencing morpholinos

Functional Ontologies
GO: Molecular:
Biological:
Cellular Component:
EC:
KOG:

Reagents		tropicalis	laevis
Clones		EXRC - 2 clone(s)
		open biosystems	open biosystems
		geneservice/RZPD imagenes	geneservice/RZPD imagenes
Affymetrix 1.0		Str.6638.1.S1_at	Xl.4715.1.S1_at [+] Xl.4715.1.S1_s_at
Affymetrix 2.0			Xl2.4715.1.S1_at

Symbol legend[+]

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