clock Summary [species: Xenopus laevis and Xenopus tropicalis] - Xenbase Gene Catalog

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Summary

Gene Literature (97)

Nucleotides (95)

Interactants (106)

XB-GENEPAGE-495447

Gene Symbol: clock Gene Name: clock circadian regulator Synonyms: clk, Xclk, XClock Add Xenopus synonyms Gene Function: circadian regulator (transcription factor) Interactants: arntl(11) , ccrn4l(9) , notch1(8) , per2(6) , cdk1(5) , per1(5) , cry1(4) View All

XB-GENE-495448

XB-GENE-6254406

Molecules		tropicalis	laevis
Gene		JGI XT Genome 7.1 JGI XT Genome 4.1 Ensembl 4.1	JGI XL Genome 6.0
		Entrez Gene	Entrez Gene
mRNA		Refseq >NM_001128655\|Xenopus (Silurana) tropicalis clock homolog (clock), mRNA GGGACGTTTAAGCAGCGATCCGGGACAGCCGGCTGTGTAGGGAAAAGCGGGACTGTCCCCGCGTAAAGCGGAGCTGCTGGGCGAGTTGAAATTAGAAATGCTGCTGCTTCACAGAACTAGAGCTGAAGCTTCTGTCTAATAGACCACTCGTCCTGCGACCAGTTCATTTTCCTGAGCTAGAGTGCTATAAGATAAGTCTACAAATGTCTCCTACGAGGCTAAAGTGTGACCTTTTCTTCTCCTTTCCATAAGCATACATAAGATGAGCTCCACTGCAGACAGAGATGACGGTAGTATTTTTGATGGACTTGTGGAAGAAGATGACAAGGATAAAGCAAAGAGGGTGTCTCGGAACAAATCGGAGAAAAGGAGAAGAGATCAGTTCAATATTCTCATTAAGGAGCTTGGCTCTATGTTGCCAGGCAATGCCCGAAGGATGGACAAATCCACTGTGCTGCAGAAAAGCATTGACTTCCTACGGAAGCATAAAGAAATTAGTGCACAGTCGGATGCTAGTGAAATACGACAAGACTGGAAACCTACGTTCCTTAGTAATGAGGAATTTACTCAACTCATGCTGGAGGCACTGGATGGATTTTTCCTGGCAGTTATGACAGATGGAAACATAATATATGTATCTGAAAGTGTGACTTCCTTACTTGAACACTTACCGTCTGATCTTGTTGATCAGAGTATATTTAATTTTGTCCCCGAGGGGGAACATTCAGAAGTGTATAAAATTCTATCTACGCGGATGTTGGAAAGTGGTTCTTTGTCATCAGAGTATCTTAAAACAAAAAATGAACTTGAATTCTGTTGCCACATGTTAAGAGGCACAGCTGACCCCAAAGAGCCATCAACCTACGAATTTGTAAAGTTTATTGGAAATTTCAAGTCCTTAAATAACGTGCCCAGCTCTACACATAATGGTTTTGATGGTGCATTACAGAGGTCACTGCGGCCGCCCTATGAAGAGAGAGTGTGCTTTGTAGCTACTGTAAGGCTAGCTACGCCACAGTTCATTAAGGAAATGTGTACTGTAGAGGAATCCACTGAAGAGTTCACATCAAGGCACAGTCTGGAATGGAAGTTTCTTTTCTTGGACCACAGGGCCCCTCCAATAATTGGATATTTGCCTTTTGAAGTGCTGGGGACTTCCGGCTATGATTACTATCATGTGGATGACCTGGAAAACCTTGCAAAATGCCATGAACACTTAATGCAGTATGGGAAAGGCAAGTCATGCTATTATAGGTTCCTGACAAAAGGGCAACAGTGGATATGGCTGCAGACACGCTATTATATCACCTACCATCAGTGGAATTCCAGGCCAGAGTTTATAGTTTGTACGCATACTGTAGTAAGCTATGCTGAGGTTGGGGCAGAAAGAAGACGTGAGCGGGGCATTGAAGATTCCCCTCCTGCCATAACTGCAGATAAAAATCAGGACTCTGTCTCAGACAATCACATGAACACAGTTAGCCTGAAGGAAGCTTTGGAAAGATTTGATGACAGCCGAACACCCTCACCATCATCCAAAAGCTCAATTAAATCATCATCTCACACTGCTGTGTCGGACCCATCATCAACACCAACAAAGATCACAACAGAAACAAGCACACCTCCCAGACAAGCTATAACTGGCCTTGACAAGAGGAGGTCGTCAGTCAGCAGCCAGTCTATGAGTTCTCAGTCAGTCAGCCAGGCGCTGTCACAGTCAGTGATGAAACAAACAGCATCTATGCAGCTCCAGCAAGGAATGGCACAGCCCATGTTTCAGTTCACGGCTCAGTTTGGAGCTATGAAGCATCTGAAGGACCAGCTGGAGCAGAGAACTCGGATCATTGAAGAAAATATCCAACGGCAACAGGAGGAGCTGCGTAAGATTCAAGAGCAGCTGCATATGGTCCATGGGCAGGGAATCCAGATGTTCTTACAACAACCAGGACCAGGGCTAAATTTTGGGCCAGTGCAAGTCTCTTCTGCAAACAGTGCAAGCATTCAGCAGTTACCACAGCTCACCATGCAAGGCCAGGTGGTCCAAACTAATCAACTTCAAGCTGGCATGAACACTGGGCATGTGGGAGCTCAGCACATAATGCAGCAGCAACAGTTACAGACTACAAGCCAGCAAGGCCAGCAGAATATTCATGGAGGGCACAGCCAGCAGACTTCTCTGTCTAGCCAGACGTCTGGAACACTCACTAGTCCTTTGTACAACACTATGGTGATCTCCCAGCCACCTTCTGGTAGTATGGTACAGATGCCTTCCAACATACAGCAGAGCAACCAGGGAGCCTCTGTCACTACATTTCCTCAGGACAGGCAGATTAGGTTTTCTCAAGCTCAACAAATTGTTACTAAGCTGGTGACCACTCCTGTGGCTTGTGGGACAGTTATGGTCCCAAGCACAATGTTTATGGGCCCAGTGGTTACTGCCTACCCTACATTTGCTACACAGCAACAGCAGCAGCAGCAGCAACCCCAGACCTTATCAATAACCCAGCACCAACCAAATCAGCAAGACCAGCAGTCAATGCCTACAGTACAGCAGCCTGCTCAAGCGCAATTAGCCCAGCAGCCACAGCAGTTTTTGCAGACCTCTAGGTTGGTCCATGGAAACCAGTCCACACAGCTCATCCTTTCCCCTTTCCCTGTGCAACAGAACACTTTTGCCCCATCACACCAGCAGCAGTTATCCCATCATAGGACTGACAGTATGAGTGATCCTTCCAAGGTGCAGCAACAGTAGTACCACTATGAGTCACGTTACACTGCTGCCTGGAAAGGAGACAATAGGATCTGGTGGCAGTTTGGCATTTATAATCACTACGGATACAGCGCAATGAATGTTTGGTACGAGGCAGCGGAGCTCATTGAGATCATGCACGGATTGAAACTTGGCATGTACAATGCTCTGCTGCTCTATGGACTTGTTTGATGCAGAAGATAATTGGACGTGCAATGTTCTACACCAGTCTGGTACTGGAGATGCCTTCACAAACCACTAGGACAGCCTGGGAAATGCTCAAATGTTTGATGAACACAGGTTATATCTTTGCCCCTTTGCTGAGGATCATAATGCTGCCCCTACTTGCCACAGGATTTCAGATTTTAATTATAGGATATCAAGTAGTTTTAGGCATTAATATAAATAATTTCATAACAGAACTATTTTAGTACATTTACACAGAATAACAAAAAATGACTATTTAACAGTTAAAGTTACATCCTACAGTACTTAATACAATATATTTTAATGTGAAGCAGTGCAGTTTTCAGGACAGCCCCTAAATAAGATTCTTGAGGTGTCCTAGTTTGTGTTATCAGAACCAAGAGAGCCAGTGGGCTCAGCACAGCAAATGTATGCATGCCTGCTGGGCCTGTGCCACTGATAGGATACATTAGCTGGGCCTGTGCCACTGATAGATACAATAGCTTCTATATCACTATTCCTAGCAGGCCTGAATACTGATCAGATTTTACATTAAGTGGAGTATGTATTAACATTGGAGGCAAACATCACTGGTGATATTGCCCATAAGTCGAAAGCAAAGGCAAAGATCTAATTGGTTGCTATGGGCAGCATCGCCAGTGATGCTTGTCCCCAGTGTTAATAAATACACTCGTGAAGTTACTAATGAATACAGCAGACTCCCATTGTGAAACCTGATCTTCATCCTTACACACTGCGCTTAGCAAATCAGCCCACGTTTGATATGAAAAGTCACTTCTGAAGTTTTTGCTTGCGGCCTGGGCTATGTTTAGCTGAGGCAGAGTGCAGCAGAACAGGTTTTTCCAGTCCCCATGATTAAACAAAAGCAGGGCTGCACACCCTTTAGCACTTTGTTCATGTCCCAGTGCTCCCCCCCCATCAGCTTCAACCAGTGGAGGATTCCGGGAGTTGTACTTCAACAACTGAAGGGCTGGAAATTGGCCGATGTGCTAATAAGTCTTACTGTTACCATCTCAGGCTACTATATCTGCCCCCTACCTACAGCCACACAGTGCCCCCTATTTGCAACCCCTACAGACAGCCCTGCCTGTGCCCTGTCAGATTATTAGGCCACTTGCTGGTAAGTTTTCATTGGCCAGTTATACTGACTGACTTGGGAACTGACCCAGCCAGATACAAATGCTTCGGCTGGATTCCAGGTTCACATTCCATGTTAGATTTTAGGTGATAGGCAAGAGATGACTTGTGCTATTACTGCCCGGAGCTAATAGGTCTCTAACTCAGGCCCAATCATCCCTTCCATGGCCCTGCCATGTCCTTCCTCTAAGCATTGGGTTCTACCATTTAATAACTGTGTTTTCCCATCGCTGTGTCAATGTATTTCTGCCTACTGACCATGCCTGTCGGCCATTTTGTTTTCAGAGCGTTGCAGGCATCTCCGGAACCAGATGAAGTAAATATCAGGTAAACCTATTCTTTTTCTGTGGGACTTGTGTGTGTTTGGTTTCAGAAATGAGACAGAATTTCACTATTTTTTTTAATGATATAACACTATTTTGAGGATGTTGGAAATCAGAGTCTATATTGTACAGCCGGTGTAAAATATTCTGTAAATACTGACATATATATATGGATAATATAAGGAAGCAGAATTTTATATGATGCATGGCTGTAGGAGTTAATGTTTCTATAAAGCCCCCCGGTTTCTGAAACACATCTCCCCCCGCCCCCACACACTTTTTAAAAAAAAAATACTTTGTTTACAGTTTTGTTGCTGTTTCTGCGTGTTCTCTTATTGGTCGATCGTATCATGTTGTGGGGAGCTATTGGTTCATTTCTGAATGCCTTCAGCGTGTCAGAGGTGTTGCTGCCCAGCCATCCATGCTTATTAGAGCCCCATTTTATCCCCATGGTTTTATATGGAAGCATTTGCACTTTTCTGCAGATGGTTTAACAGAAAAAACTCTTACCTCTCAAAGCTTTGTCTATTTATGTCAAAAATGTTAAGCTAAAAAAAAACCTTAAGAAACTACTTATTGGAAGTTCCGTTCTAGGAGTGTTTTTTACAAAATGATATACAAATATATATACAGTGTATTTTTACCATATGTATGTGTTGTAAAGGAAAGTGATTTACTCTCACTAAGTGTCTCCTTTGCAGTGCATCCTCACACATGCTTTACTGGTGTCTGGCGCTGCCGCTGGGGTGCCCCCTGTTATTGGGGTGCTCGGTGTGCCTACACCTCAGTGCTAATGAAGTGCTTATTGGAGAGGAACTGTCATTGCTATCAAATGCACCCAAATTGTAGTGGATGTTAAATAAATCTCTTCCACAAAAAAAAAAAAAAAAAA	Refseq >NM_001090385\|Xenopus laevis clock homolog (clock), mRNA CACACGAGCCAAGGAGCTGGATATTAACTGCGTTGCGGGACGTTTAAGAAGAGATCGGGGACTGCGGGCTGTGTTGCCAAAATTGAGGCTGTCCCGCGAAAAGTGCTACATTTGGGCGGGTTGAAATTAGAAATGCTGCTGTGTCACAGAAACTTGAGCTGAAGCTTTCTTCTAATAGACCATCCTGCAACCAATTAATTTCCTGGGCTAAAGTGCTTGTAAGATACATCTACAAATGTCTCCTACGAGGCTCAAGTGTGACCTTTTCTTCTCCTTTCCATAAGCATACATAAGATGAGCTCCACTGCAGACAGAGATGACGGTAGTATATTTGATGGACTGGTAGAAGAAGATGACAAGGATAAAGCAAAGAGGGTGTCTCGGAACAAATCGGAGAAACGGAGAAGAGATCAGTTCAATATTCTCATTAAGGAGCTTGGGTCTATGTTGCCAGGCAATGCCAGAAGAATAGACAAATCCACAGTGCTGCAGAAAAGCATTGACTTCCTACAGAAGCATAAAGAAATCAGTGCACAGTCGGATGCTAGCGAAATACGACAAGACTGGAAACCTACTTTCCTTAGTAATGAAGAATTTACTCAACTCATGCTGGAGGCGCTGGATGGATTTTTCCTGGCAGTTATGACAGATGGAAACATAATATATGTATCTGAAAGCGTGACCTCCTTACTTGAACACTTACCATCTGATCTTGTTGATCAGAGTATATTTAATTTTGTCCCCGAGGGGGAACATTCAGAAGTGTATAAAATTCTGTCTACGCGGATGTTGGAAAGTGGTTCTTTGTCATCGGAGTATCTTAAAACAAAAAATGAACTAGAATTCTGTTGCCACATGCTAAGAGGCACAGCCGATCCTAAAGAGCCATCAACGTACGAATTTGTAAAGTTTATTGGAAACTTCAAGTCTTTAAATAATGTGCCCAACTCTACACATAATGGATTTGATGGTGCATTACAGAGGTCTCTGCGGCCACCCTATGAAGAGAGAGTGTGCTTTGTAGCCACTGTAAGGCTAGCTACTCCACAGTTCATTAAGGAAATGTGCACTGTAGAGGAATCCAATGAAGAGTTCACATCAAGGCACAGTCTGGAATGGAAGTTTCTTTTCTTGGACCACAGGGCCCCTCCAATCATTGGATATTTGCCTTTTGAGGTGCTAGGAACTTCTGGCTATGATTATTATCACGTGGATGACCTGGAAAACCTTGCAAAATGCCATGAACACTTAATGCAGTATGGAAAAGGCAAGTCATGCTATTACAGGTTCCTGACAAAAGGACAGCAATGGATATGGCTGCAGACGCGCTACTATATCACCTACCATCAGTGGAATTCCAGGCCAGAGTTTATAGTTTGTACGCATACTGTAGTAAGCTATGCAGAGGTTGGAGCAGAAAGAAGACGTGAGCGGGGCAATGAAGATTCCCCTCCTGCCATAACTGCAGAAAAAAATCAGGACTCTGTCTCAGACAATCACATGAACACAGTCAGTCTGAAGGAAGCTTTGGAAAGATTTGATGACAGCCGAACGCCTTCACCGTCATCCAAAAGCTCAATTAAATCATCCTCTCACACAGCAGTTTCCGACCCATCATCAACGCCAACAAAGATCCCAACAGACACAAGCACACCACCTAGACAAGCTTTAACTGGCCTTGACAAGAGGAGGTCATCAATCAGCAGCCAGTCTATGAGCTCTCAGTCAGTCAGTCAGCCTCTGTCGCAGTCAGTGATGAAGCAAACAGCATCTATTCAGCTCCAGCAAGGAATGACACAGCCCATGTTTCAGTTCACGGCGCAGTTTGGAGCTATGAAGCACCTGAAGGACCAGCTGGAGCAGAGAACTCGGATCATTGAAGAAAACATCCAGCGGCAGCAGGAGGAGCTGCGTAAGATTCAGGACCAGTTGCAAATGGTCCATGGGCAGGGAATCCAGATGTATTTACAGCAACCAGCACCAGGGCTAAATTTTGGGCCAGTACAGTACTCTTCTGGAAATAGCCCAAGCATTCAGCAGTTACCGCAGTTCACCATGCAAGGCCAAGTGGTCCAGACTAACCAACTTCAAGGTGTCATGAACACTGGGCATGTGGGAGCTCAGCACATAATGCAGCAGCAACAGTTACACAATACAAGCCAGCAAGGCCAGCAGAACATTCATGGAGGACACAACCAGCAGACTTCACTGTCTAGCCAGACATCGGGAACTCTCACTAGTCCTTTGTACAACACAATGGTGATCTCCCAGCCACCTTCAGGTAGTATGGTACAGATGCCTTCCAACATACAGCAGAGCAACCAGGGAGCCTCTGTTACTACATTTCCTCAGGACAGGCAGATTAGGTTTTCTCAAGCTCAGCAAATTGTCACTAAGCTGGTGACCACTCCTATGGCTTGTGGAACAGTTATGGTCCCAAGCACAATGTTTATGGGCCCAGTGGTTACTGCCTACCCTACATTTACTACACAGCAGCAGCAACCTCAAACCTTATCATTCACCCAGCATCAACAAAATCAGCAAGACCAACAGACAGTGCCTACAATACAGCAGCCTGCTCACGCACAACTAGCCCAGCAGCCACAACAGTTTTTGCAGACCTCGAGGTTGGTTCATGGAAACCAGTCCACACAGCTGATTCTTTCCCCTTTCCCTGTGCAACAGAACACTTTTGCCCCATCCCACCAGCAGCAGTTATCCCATCACAGGACTGACACTATGAGTGATCCTTCCAAGGTGCAGCAACAGTAGTACCACTATGAGTCCCTTTAAACTGCTGTCTGAAAGAGATGACAGAATTTGGCGGAATTATGGCGTTTATAATCACTATGGATACAGCGCAATGAATGTTTGGTACGAGGCAGCAGAGCTCGCTGAGATCAGGCACCAACTGAAACTCGGCATGTGCGATGCTCTGCTGCACTACAGACTAGTCAGGCGTAGAACATAATAGACGTGCAATGCTCTAGACAACTCTGCTACTGGAGATGCCTTCAACAACCACTAGGACAGGCCCCCGCTATATATTATATTCTTCTATTTCTGCCCTTATGCTGAGGGAATATATTGCTCTCTCTCGGCACGAGC
Protein		Refseq >NP_001122127\|clock [Xenopus (Silurana) tropicalis] MSSTADRDDGSIFDGLVEEDDKDKAKRVSRNKSEKRRRDQFNILIKELGSMLPGNARRMDKSTVLQKSIDFLRKHKEISAQSDASEIRQDWKPTFLSNEEFTQLMLEALDGFFLAVMTDGNIIYVSESVTSLLEHLPSDLVDQSIFNFVPEGEHSEVYKILSTRMLESGSLSSEYLKTKNELEFCCHMLRGTADPKEPSTYEFVKFIGNFKSLNNVPSSTHNGFDGALQRSLRPPYEERVCFVATVRLATPQFIKEMCTVEESTEEFTSRHSLEWKFLFLDHRAPPIIGYLPFEVLGTSGYDYYHVDDLENLAKCHEHLMQYGKGKSCYYRFLTKGQQWIWLQTRYYITYHQWNSRPEFIVCTHTVVSYAEVGAERRRERGIEDSPPAITADKNQDSVSDNHMNTVSLKEALERFDDSRTPSPSSKSSIKSSSHTAVSDPSSTPTKITTETSTPPRQAITGLDKRRSSVSSQSMSSQSVSQALSQSVMKQTASMQLQQGMAQPMFQFTAQFGAMKHLKDQLEQRTRIIEENIQRQQEELRKIQEQLHMVHGQGIQMFLQQPGPGLNFGPVQVSSANSASIQQLPQLTMQGQVVQTNQLQAGMNTGHVGAQHIMQQQQLQTTSQQGQQNIHGGHSQQTSLSSQTSGTLTSPLYNTMVISQPPSGSMVQMPSNIQQSNQGASVTTFPQDRQIRFSQAQQIVTKLVTTPVACGTVMVPSTMFMGPVVTAYPTFATQQQQQQQQPQTLSITQHQPNQQDQQSMPTVQQPAQAQLAQQPQQFLQTSRLVHGNQSTQLILSPFPVQQNTFAPSHQQQLSHHRTDSMSDPSKVQQQ	Refseq >NP_001083854\|clock homolog [Xenopus laevis] MSSTADRDDGSIFDGLVEEDDKDKAKRVSRNKSEKRRRDQFNILIKELGSMLPGNARRIDKSTVLQKSIDFLQKHKEISAQSDASEIRQDWKPTFLSNEEFTQLMLEALDGFFLAVMTDGNIIYVSESVTSLLEHLPSDLVDQSIFNFVPEGEHSEVYKILSTRMLESGSLSSEYLKTKNELEFCCHMLRGTADPKEPSTYEFVKFIGNFKSLNNVPNSTHNGFDGALQRSLRPPYEERVCFVATVRLATPQFIKEMCTVEESNEEFTSRHSLEWKFLFLDHRAPPIIGYLPFEVLGTSGYDYYHVDDLENLAKCHEHLMQYGKGKSCYYRFLTKGQQWIWLQTRYYITYHQWNSRPEFIVCTHTVVSYAEVGAERRRERGNEDSPPAITAEKNQDSVSDNHMNTVSLKEALERFDDSRTPSPSSKSSIKSSSHTAVSDPSSTPTKIPTDTSTPPRQALTGLDKRRSSISSQSMSSQSVSQPLSQSVMKQTASIQLQQGMTQPMFQFTAQFGAMKHLKDQLEQRTRIIEENIQRQQEELRKIQDQLQMVHGQGIQMYLQQPAPGLNFGPVQYSSGNSPSIQQLPQFTMQGQVVQTNQLQGVMNTGHVGAQHIMQQQQLHNTSQQGQQNIHGGHNQQTSLSSQTSGTLTSPLYNTMVISQPPSGSMVQMPSNIQQSNQGASVTTFPQDRQIRFSQAQQIVTKLVTTPMACGTVMVPSTMFMGPVVTAYPTFTTQQQQPQTLSFTQHQQNQQDQQTVPTIQQPAHAQLAQQPQQFLQTSRLVHGNQSTQLILSPFPVQQNTFAPSHQQQLSHHRTDTMSDPSKVQQQ

Genomic		tropicalis
Genome Browser		Xenbase	Xenbase JGI Ensembl UCSC		Xenbase

Synteny		Metazome

Expression		tropicalis	laevis
UniGene		Str.8829	Xl.566 [+] Xl.72512 Xl.74449
Unigene EST Profile		EST Profile	EST Profile
GEO data			GEO
Images		1 expression image(s) for tropicalis and laevis

Orthology		MOD	Entrez Gene	Genetic Phenotypes	Morphants
human		OMIM:Gene, HGNC	CLOCK
mouse		MGI	Clock	All(4) Targeted, knock Out(2) Chemically Induced(1) Targeted, other(1)
zebrafish		ZFIN	clock	2 Lines(s)

Publications
First:		Albumin evolution in frogs: a test of the evolutionary clock hypothesis. [Proc Natl Acad Sci U S A 1971]
Most recent:		The Cdk1-APC/C cell cycle oscillator circuit functions as a time-delayed, ultrasensitive switch. [Nat Cell Biol 2013]
		View All Papers 2 paper(s) referencing morpholinos

Functional Ontologies
GO: Molecular:		signal transducer activity transcription factor activity
Biological:		regulation of transcription, DNA-dependent signal transduction
Cellular Component:		nucleus
EC:
KOG:		[K] Aryl-hydrocarbon receptor nuclear translocator

Reagents		tropicalis	laevis
Clones		open biosystems	open biosystems
		geneservice/RZPD imagenes	geneservice/RZPD imagenes
Affymetrix 1.0		StrJgi.1698.1.S1_at [+] Str.8829.1.A1_at Str.26995.1.S1_s_at Str.26995.1.S1_at StrEns.3055.1.S1_s_at	Xl.566.2.S1_at [+] Xl.566.1.S1_at Xl.26267.1.A1_at
Affymetrix 2.0			Xl2.566.1.S1_at [+] Xl2.566.2.S1_at

Symbol legend[+]