Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Summary Expression Gene Literature (30) GO Terms (9) Nucleotides (55) Proteins (30) Interactants (372) Wiki
Gene Symbol:

Gene Name:
engrailed homeobox 1

xen1 , en-1 , engrailed-1 , engrailed 1 , eng1 , en1-a , en1-b ( Add synonyms , Nomenclature history )

Gene Function:
homeodomain transcription factor

Protein Function :

Loading ...


External Links:
Xenbase Gene ID XB-GENE-5737237 XB-GENE-6254268 XB-GENE-5737240
Gene Symbol en1 en1.L en1.S
Chromosome scaffold_5298 chr9_10L chr9_10S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 9.1 Version 9.2 Version 9.2
CDS Gene model Gene model Gene model
Entrez Gene 100493090
mRNA NCBI Nucleotide RefSeq NCBI Nucleotide
Protein NCBI Protein NCBI Protein NCBI Protein RefSeq  More.. NCBI Protein NCBI Protein  More..
X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine en1 en1.L en1.S
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
HGNC AGR, OMIM:Gene, GeneCards EN1 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
MGI, AGR En1 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
RGD, AGR En1 Ensembl
ZFIN, AGR ZFIN, AGR en1a en1b ZFIN Ensembl
GEISHA EN1 Ensembl
fruit fly
First Examining pattern formation in mouse, chicken and frog embryos with an En-specific antiserum., Development 1991            
Most Recent Bioinformatics Screening of Genes Specific for Well-Regenerating Vertebrates Reveals c-answer, a Regulator of Brain Development and Regeneration., Cell Rep 2019                                
All View All Papers 6 paper(s) referencing morpholinos 2 paper(s) referencing OMIMs 1 paper(s) referencing Disease Ontology
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 7 terms 4 terms 4 terms
KEGG Pathways K09319 K09319
KOG [R] Transcription factor Engrailed, contains HOX domain
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks en1
Antibodies En2 Ab3 , Neuronal Ab5 , En2 Ab1 En2 Ab1 , En2 Ab3 , Neuronal Ab5 En2 Ab1 , En2 Ab3 , Neuronal Ab5
Morpholinos en1 MO1 , en1 MO2 en1 MO1 , en1 MO2 en1 MO1 , en1 MO2
ORFs en1.L ORF1
Clones Horizon Source BioScience Horizon Source BioScience Horizon Source BioScience
Plasmids Addgene Addgene

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info   [+] Expand list
Xenbase: The Xenopus Model Organism Knowledgebase.
Version: 4.15.0
Major funding for Xenbase is provided by grant P41 HD064556