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Summary Expression Gene Literature (20) GO Terms (16) Nucleotides (210) Proteins (36) Interactants (424) Wiki
XB-GENEPAGE-5759105
Gene Symbol:
vcl

Gene Name:
vinculin

Synonyms:
( Add synonyms , Nomenclature history )

Gene Function:
cytoskeletal protein

Protein Function :
Involved in cell adhesion. May be involved in the attachment of the actin-based microfilaments to the plasma membrane.


InterPro :
Argonaute hook dom , Nucleotide-bd a/b plait sf , TNRC6A RRM , TNRC6 PABC-bd [+]

Interactants:
Loading ...

Diseases: 


Disease Ontology:
hypertrophic cardiomyopathy 15 [+]

OMIM:
CARDIOMYOPATHY, DILATED, 1W; CMD1W [+]

External Links:
 
Xenbase Gene ID XB-GENE-5759106 XB-GENE-17331397 XB-GENE-5759162
Gene Symbol vcl vcl.L vcl.S
Chromosome Chr7 Scaffold19
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.1
CDS Gene model Gene model
Entrez Gene 100036705
373770
mRNA NCBI Nucleotide NCBI Nucleotide
Protein NCBI Protein RefSeq  More.. NCBI Protein NCBI Protein  More..
Genomic
 X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics X. tropicalis X. laevis.L X. laevis.S
Embryonic Protein Expression Stage profile:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine vcl vcl.L vcl.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards VCL OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Vcl MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Vcl Ensembl
zebrafish
ZFIN, AGR ZFIN, AGR vcla vclb ZFIN Ensembl
chicken
GEISHA VCL Ensembl
fruit fly
worm
Publications
First Cytoskeletal components of the vertebrate neuromuscular junction: vinculin, alpha-actinin, and filamin., J Cell Biol 1983            
Most Recent Xenopus to the rescue: A model to validate and characterize candidate ciliopathy genes., Genesis 2021    
All View All Papers 2 paper(s) referencing morpholinos 1 paper(s) referencing OMIMs 3 paper(s) referencing Disease Ontology
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 12 terms 0 term 7 terms
PANTHER vcl
KEGG Pathways K05700
KOG [W] Alpha-catenin
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks vcl
Antibodies Vcl Ab1 , Vcl Ab2 , Vcl Ab3 Vcl Ab2 , Vcl Ab3 Vcl Ab1 , Vcl Ab2 , Vcl Ab3
Morpholinos (on-target & off-target) vcl MO1
Clones Horizon Source BioScience Horizon Source BioScience
Plasmids Addgene Addgene

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