Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Summary Expression Gene Literature (275) GO Terms (5) Nucleotides (2530) Proteins (45) Interactants (634) Wiki
XB-GENEPAGE-5776261
Gene Symbol:
prss1

Gene Name:
serine protease 1

Synonyms:
trypsin , trp1 , try1 ( Add synonyms , Nomenclature history )

Gene Function:
This gene encodes a trypsinogen, which is a member of the trypsin family of serine proteases

Protein Function :


InterPro :
Peptidase S1A , Peptidase S1 PA , Trypsin dom , TRYPSIN HIS [+]

Interactants:
Loading ...

Diseases: 


Disease Ontology:
pancreatitis

OMIM:
PANCREATITIS, HEREDITARY; PCTT [+]

External Links:
 
Xenbase Gene ID XB-GENE-5776262 XB-GENE-5776767 XB-GENE-17334863
Gene Symbol prss1 prss1.L prss1.S
Chromosome scaffold_486 chr7L chr7S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 9.1 Version 9.2 Version 9.2
CDS Gene model Gene model Gene model
Entrez Gene 548509
397853
108697139
mRNA RefSeq NCBI Nucleotide NCBI Nucleotide
Protein NCBI Protein RefSeq NCBI Protein Swiss-Prot  More.. NCBI Protein
Genomic
 X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine prss1 prss1.L prss1.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards PRSS1 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Prss1 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Prss1 Ensembl
zebrafish
ZFIN, AGR prss1 ZFIN Ensembl
chicken
GEISHA LOC107048991 Ensembl
fruit fly
worm
Publications
First The mucosubstance coating the pneumonocytes in the lungs of Xenopus laevis and Lacerta viridis., Histochem J 1975  
Most Recent Novel Mutations in the TMPRSS3 Gene may Contribute to Taiwanese Patients with Nonsyndromic Hearing Loss., Int J Mol Sci 2020                
All View All Papers 5 paper(s) referencing morpholinos 3 paper(s) referencing OMIMs 5 paper(s) referencing Disease Ontology
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 3 terms 4 terms 0 term
PANTHER prss1
KEGG Pathways K01312 K01312
KOG [E] Trypsin
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks prss1
ORFs prss1 ORF1 prss1.L ORF1
Clones Horizon Source BioScience Horizon Source BioScience Horizon
Plasmids Addgene Addgene

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info   [+] Expand list
Xenbase: The Xenopus Model Organism Knowledgebase.
Version: 4.15.0
Major funding for Xenbase is provided by grant P41 HD064556