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Summary Expression Gene Literature (9) GO Terms (16) Nucleotides (245) Proteins (63) Interactants (599) Wiki
XB-GENEPAGE-5799693
Gene Symbol:
tcf12

Gene Name:
transcription factor 12 (HTF4, helix-loop-helix transcription factors 4)

Synonyms:
HEB , XE1.1 ( Add synonyms , Nomenclature history )

Gene Function:
helix-loop-helix transcription factor

Protein Function :
Transcriptional regulator. Involved in the initiation of neuronal differentiation. Activates transcription by binding to the E box-containing promoter.


InterPro :
Gastrin rcpt , GPCR Rhodpsn 7TM , Cholcskin rcpt , GPCR Rhodpsn [+]

Interactants:
Loading ...

Diseases: 


Disease Ontology:
craniosynostosis

OMIM:
CRANIOSYNOSTOSIS 3; CRS3

External Links:
1/3
 
Xenbase Gene ID XB-GENE-5799694 XB-GENE-5799717 XB-GENE-17341445
Gene Symbol tcf12 tcf12.L tcf12.S
Chromosome Chr03 chr3L chr3S
Molecules tropicalis laevis.L laevis.S
Genomic Sequence Version 9.1 Version 9.2 Version 9.2
CDS Gene model Gene model Gene model
Entrez Gene 100188922
399451
398335
mRNA NCBI Nucleotide NCBI Nucleotide NCBI Nucleotide
Protein NCBI Protein NCBI Protein NCBI Protein
Genomic
 tropicalis laevis.L laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics tropicalis laevis.L laevis.S
Embryonic Protein Expression Stage profile: Stage profile:
Data Mining tropicalis laevis.L laevis.S
XenMine tcf12 tcf12.L tcf12.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards TCF12 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Tcf12 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Tcf12 Ensembl
zebrafish
ZFIN, AGR tcf12 ZFIN Ensembl
chicken
GEISHA TCF12 Ensembl
fruit fly
worm
Publications
First Identification of non-tissue-specific helix-loop-helix genes in Xenopus laevis., Gene 1995  
Most Recent Id genes are essential for early heart formation., Genes Dev 2017                  
All View All Papers 2 paper(s) referencing morpholinos 1 paper(s) referencing Disease Ontology
Functional Ontologies tropicalis laevis.L laevis.S
GO 14 terms 5 terms 1 terms
PANTHER tcf12
KEGG Pathways
KOG [K] Helix loop helix transcription factor
Reagents tropicalis laevis.L laevis.S
CRISPRscan Tracks tcf12
Morpholinos tcf12 MO1 , tcf12 MO2 tcf12 MO1 , tcf12 MO2 tcf12 MO1 , tcf12 MO2
ORFs MGC83272 ORF2
Clones Horizon Source BioScience Horizon Source BioScience Horizon

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info   [+] Expand list
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