Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Summary Expression Gene Literature (10) GO Terms (18) Nucleotides (256) Proteins (66) Interactants (633) Wiki
XB-GENEPAGE-5799693
Gene Symbol:
tcf12

Gene Name:
transcription factor 12 (HTF4, helix-loop-helix transcription factors 4)

Synonyms:
HEB , XE1.1 ( Add synonyms , Nomenclature history )

Gene Function:
helix-loop-helix transcription factor

Protein Function :
Transcriptional regulator. Involved in the initiation of neuronal differentiation. Activates transcription by binding to the E box-containing promoter.



Interactants:
Loading ...

Diseases: 


Disease Ontology:
craniosynostosis

OMIM:
CRANIOSYNOSTOSIS 3; CRS3

External Links:
1/3
 
Xenbase Gene ID XB-GENE-5799694 XB-GENE-5799717 XB-GENE-17341445
Gene Symbol tcf12 tcf12.L tcf12.S
Chromosome Chr3 chr3L chr3S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.2 Version 9.1
CDS Gene model Gene model Gene model
Entrez Gene 100188922
399451
398335
mRNA NCBI Nucleotide NCBI Nucleotide NCBI Nucleotide
Protein NCBI Protein NCBI Protein  More.. NCBI Protein NCBI Protein  More.. NCBI Protein NCBI Protein  More..
Genomic
X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics X. tropicalis X. laevis.L X. laevis.S
Embryonic Protein Expression Stage profile: Stage profile:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine tcf12 tcf12.L tcf12.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards TCF12 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Tcf12 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Tcf12 Ensembl
zebrafish
ZFIN, AGR tcf12 ZFIN Ensembl
chicken
GEISHA TCF12 Ensembl
fruit fly
worm
Publications
First Identification of non-tissue-specific helix-loop-helix genes in Xenopus laevis., Gene 1995  
Most Recent Epigenetic homogeneity in histone methylation underlies sperm programming for embryonic transcription., Nat Commun 2020                
All View All Papers 2 paper(s) referencing morpholinos 1 paper(s) referencing Disease Ontology
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 17 terms 5 terms 1 terms
PANTHER tcf12
KEGG Pathways
KOG [K] Helix loop helix transcription factor
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks tcf12
Morpholinos (on-target & off-target) tcf12 MO1 , tcf12 MO2 tcf12 MO1 , tcf12 MO2 tcf12 MO1 , tcf12 MO1 , tcf12 MO2
ORFs MGC83272 ORF2
Clones Horizon Source BioScience Horizon Source BioScience Horizon
Plasmids Addgene Addgene

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info