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Summary Expression Gene Literature (128) GO Terms (9) Nucleotides (507) Proteins (44) Interactants (274) Wiki
XB-GENEPAGE-5810263
Gene Symbol: tpx2

Gene Name: TPX2, microtubule-associated

Synonyms: dil2 , dil-2 , hctp4 , repp86 , tpx2-a , tpx2-b ( Add synonyms , Nomenclature history )

Gene Function: Immunoglobin and related proteins

Protein Function :
Spindle assembly factor. Required for normal assembly of mitotic spindles. Mediates the binding kif15 and aurka to spindle microtubules. Required for targeting kif15 to microtubule minus ends. Activate...[+]

Interactants: Loading ...
Disease Ontology: prostate cancer

OMIM Diseases: PROSTATE CANCER

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Xenbase Gene ID XB-GENE-5810264 XB-GENE-6251919 XB-GENE-6255926
Gene Symbol tpx2 tpx2.L tpx2.S
Chromosome scaffold_4312 Scaffold147859 Scaffold60603
Molecules tropicalis laevis.L laevis.S
Gene Genomic sequence
CDS Gene model
Entrez Gene
Entrez Gene
Entrez Gene
mRNA RefSeq RefSeq RefSeq
Protein RefSeq TrEMBL Swiss-Prot RefSeq TrEMBL Swiss-Prot RefSeq Swiss-Prot
Genomic tropicalis laevis.L laevis.S
Genome Browser
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics tropicalis laevis.L laevis.S
Embryonic Protein Expression
Data Mining tropicalis laevis.L laevis.S
XenMine tpx2 tpx2.L tpx2.S
Phenotype tropicalis laevis.L laevis.S
Smith Morpholino Screen    
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM:Gene, HGNC, GeneCards TPX2 OMIM, MalaCards, KEGG Disease, DECIPHER Ensembl, Protein Atlas, Allen Brain Atlas
mouse
MGI, AGR Tpx2 MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
zebrafish
ZFIN, AGR tpx2 ZFIN Ensembl
chicken
GEISHA TPX2 Ensembl
fruit fly
worm
WORMBASE
Publications
First Localization of the kinesin-like protein Xklp2 to spindle poles requires a leucine zipper, a microtubule-associated protein, and dynein., J Cell Biol 1998                  
Most Recent TPX2 silencing exerts anti‑tumor effects on hepatocellular carcinoma by regulating the PI3K/AKT signaling pathway., Int J Mol Med 2019            
All View All Papers 2 paper(s) referencing morpholinos 3 paper(s) referencing OMIMs 6 paper(s) referencing Disease Ontology
Functional Ontologies tropicalis laevis.L laevis.S
GO 9 terms 9 terms 8 terms
PANTHER tpx2
KEGG Pathways K16812 K16812 K16812
KOG [RP] FOG: Immunoglobin and related proteins
Reagents tropicalis laevis.L laevis.S
CRISPR / TALEN CRISPR tools CRISPR tools CRISPR tools
Clones
Dharmacon Dharmacon Dharmacon
Morpholino tpx2 MO1 tpx2 MO1 tpx2 MO1
ORF tpx2 ORF1 tpx2.S ORF1
Affymetrix 1.0 Str.45402.1.A1_at [+] Xl.4592.2.A1_at
Affymetrix 2.0 Xl2.658.1.S1_at Xl2.4592.1.S1_at

Symbol legend: - Blast this sequence    - View this sequence       - Literature or expression images  
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