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Summary Expression Gene Literature (5) GO Terms (18) Nucleotides (254) Proteins (29) Interactants (29) Wiki
XB-GENEPAGE- 5821473

Gene Symbol: uhrf1

Gene Name: ubiquitin-like with PHD and ring finger domains 1

Synonyms:
Add Xenopus synonyms , Nomenclature history

Gene Function: zinc-finger protein

Protein Function :
Multidomain protein that acts as a key epigenetic regulator by bridging DNA methylation and chromatin modification. Specifically recognizes and binds hemimethylated DNA at replication forks via its YDG...[+]


Interactants: Loading ...

Disease Ontology:
  

OMIM Diseases:
  
 

Xenbase Gene ID XB-GENE-5821474 XB-GENE-17344332 XB-GENE-5821540
Gene Symbol uhrf1 uhrf1.L uhrf1.S
Chromosome Chr01 chr1L chr1S
Molecules tropicalis laevis.L laevis.S
Gene Genomic sequence Genomic sequence Genomic sequence
CDS Gene model
Entrez Gene
Entrez Gene
Entrez Gene
mRNA NCBI Nucleotide Refseq
Protein NCBI Protein Refseq Swiss-Prot
Genomic tropicalis laevis.L laevis.S
Genome Browser
Links
Genomic Synteny Genomicus
Expression tropicalis laevis.L laevis.S
Ensembl Ensembl
UniGene Str.41698 [+] [+]
RNA-Seq profile Stage profile: Stage profile:       Tissue heatmap:
Experimental regulation Regulation heatmap:
Images 14 expression image(s) for tropicalis and laevis
Data Mining tropicalis laevis.L laevis.S
XenMine uhrf1 uhrf1.L uhrf1.S
Phenotype tropicalis laevis.L laevis.S
Smith Morpholino Screen    
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM:Gene, HGNC, GeneCards UHRF1 OMIM, MalaCards, KEGG Disease, DECIPHER Ensembl, Protein Atlas, Allen Brain Atlas
mouse
MGI, AGR Uhrf1 MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
zebrafish
ZFIN, AGR uhrf1 ZFIN Ensembl
chicken
GEISHA UHRF1 Ensembl
fruit fly
worm
WORMBASE
Publications
First: Depletion of Uhrf1 inhibits chromosomal DNA replication in Xenopus egg extracts. [Nucleic Acids Res 2013]
Most recent: Structure of the Dnmt1 Reader Module Complexed with a Unique Two-Mono-Ubiquitin Mark on Histone H3 Reveals the Basis for DNA Methylation Maintenance. [Mol Cell 2017]
View All Papers
Functional Ontologies tropicalis laevis.L laevis.S
GO 0 term 0 term 18 terms
PANTHER uhrf1
KEGG Pathways K10638
KOG [R] PHD Zn-finger protein
Reagents tropicalis laevis.L laevis.S
CRISPR / TALEN CRISPR tools CRISPR tools CRISPR tools
Clones
GE Dharmacon GE Dharmacon GE Dharmacon
Source BioScience
Antibody Uhrf1 Ab1 , Uhrf1 Ab2 , Uhrf1 Ab3 Uhrf1 Ab3 Uhrf1 Ab1 , Uhrf1 Ab2 , Uhrf1 Ab3
Affymetrix 1.0 Str.41698.1.A1_at [+] Xl.23750.1.S1_at [+]
Affymetrix 2.0 Xl2.55524.1.S1_x_at [+]

Symbol legend[+]
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