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Summary Expression Gene Literature (5) GO Terms (6) Nucleotides (90) Proteins (26) Interactants (85) Wiki
XB-GENEPAGE- 5823873

Gene Symbol: cacna1s

Gene Name: calcium channel, voltage-dependent, L type, alpha 1S subunit

Synonyms: cav1.1 , ca(v)1.1 , DHPR, alpha sub-unit
Add Xenopus synonyms , Nomenclature history


Gene Function: calcium ion transport

Protein Function :
Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone...[+]


Interactants: Loading ...

Disease Ontology:
   HYPOKALEMIC PERIODIC PARALYSIS

OMIM Diseases:
   HYPOKALEMIC PERIODIC PARALYSIS, TYPE 1; HOKPP1 [+]
 

Xenbase Gene ID XB-GENE-5823874 XB-GENE-17331165 XB-GENE-5823879
Gene Symbol cacna1s cacna1s.L cacna1s.S
Chromosome Chr02 chr2L chr2S
Molecules tropicalis laevis.L laevis.S
Gene Genomic sequence Genomic sequence Genomic sequence
CDS Gene model
Entrez Gene
Entrez Gene
mRNA NCBI Nucleotide NCBI Nucleotide
Protein NCBI Protein TrEMBL TrEMBL TrEMBL NCBI Protein TrEMBL
Genomic tropicalis laevis.L laevis.S
Genome Browser
Links
Genomic Synteny Genomicus PANTHER
Expression tropicalis laevis.L laevis.S
Ensembl Ensembl
UniGene Str.29286 [+] Xl.57854 [+]
RNA-Seq profile Stage profile: Stage profile:       Tissue heatmap:
Experimental regulation Regulation heatmap:
Images 10 expression image(s) for tropicalis and laevis
Data Mining tropicalis laevis.L laevis.S
XenMine cacna1s cacna1s.L cacna1s.S
Phenotype tropicalis laevis.L laevis.S
Smith Morpholino Screen    
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM:Gene, HGNC, GeneCards CACNA1S OMIM, MalaCards, KEGG Disease, DECIPHER Ensembl, Protein Atlas, Allen Brain Atlas
mouse
MGI, AGR Cacna1s MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
zebrafish
ZFIN, AGR ZFIN, AGR cacna1sa cacna1sb ZFIN Ensembl
chicken
GEISHA CATSPER2 Ensembl
fruit fly
worm
WORMBASE
Publications
First: Expression of L-type Ca2+ channel during early embryogenesis in Xenopus laevis. [Int J Dev Biol 1995]
Most recent: Stac3 enhances expression of human CaV1.1 in Xenopus oocytes and reveals gating pore currents in HypoPP mutant channels. [J Gen Physiol 2018]
View All Papers 1 paper(s) referencing OMIMs 1 paper(s) referencing Disease Ontology
Functional Ontologies tropicalis laevis.L laevis.S
GO 5 terms 0 term 3 terms
PANTHER cacna1s
KEGG Pathways K04857
KOG [PT] Voltage-gated Ca2+ channels, alpha1 subunits
Reagents tropicalis laevis.L laevis.S
CRISPR / TALEN CRISPR tools CRISPR tools CRISPR tools
Clones
GE Dharmacon GE Dharmacon GE Dharmacon
Source BioScience Source BioScience
Antibody Cacna1s Ab1 , Cacna1s Ab2 Cacna1s Ab1 , Cacna1s Ab2
Affymetrix 1.0 Str.29286.1.S1_at Xl.11094.1.S1_at
Affymetrix 2.0 Xl2.11094.1.S1_at

Symbol legend[+]
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