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Summary Expression Gene Literature (16) GO Terms (17) Nucleotides (116) Proteins (35) Interactants (78) Wiki
XB-GENEPAGE-5829757
Gene Symbol:
dbf4b

Gene Name:
DBF4 zinc finger B

Synonyms:
dbf4 , Drf1 ( Add synonyms , Nomenclature history )

Gene Function:
Protein kinase essential for the initiation of DNA replication

Protein Function :
Regulatory subunit for cdc7 which activates its kinase activity thereby playing a central role in DNA replication and cell proliferation. Specifically required during the initiation of DNA replication ...[+]



Interactants:
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Diseases: 


External Links:
 
Xenbase Gene ID XB-GENE-5829758 XB-GENE-5829790 XB-GENE-17339658
Gene Symbol dbf4b dbf4b.L dbf4b.S
Chromosome Chr10 chr9_10L
Molecules tropicalis laevis.L laevis.S
Genomic Sequence Version 9.1 Version 9.2
CDS Gene model Gene model
Entrez Gene 100379975
398696
mRNA NCBI Nucleotide RefSeq
Protein NCBI Protein RefSeq Swiss-Prot Swiss-Prot
Genomic
tropicalis laevis.L laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics tropicalis laevis.L laevis.S
Embryonic Protein Expression Stage profile:
Data Mining tropicalis laevis.L laevis.S
XenMine dbf4b dbf4b.L dbf4b.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards DBF4B OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
rat
RGD, AGR Dbf4b Ensembl
zebrafish
ZFIN, AGR dbf4b ZFIN Ensembl
chicken
GEISHA DBF4B Ensembl
fruit fly
worm
Publications
First Sensitivity of the origin decision point to specific inhibitors of cellular signaling and metabolism., Exp Cell Res 2002  
Most Recent Chk1 Inhibition of the Replication Factor Drf1 Guarantees Cell-Cycle Elongation at the Xenopus laevis Mid-blastula Transition., Dev Cell 2017                  
All View All Papers
Functional Ontologies tropicalis laevis.L laevis.S
GO 15 terms 5 terms 0 term
PANTHER dbf4b
KEGG Pathways
KOG [LD] Protein kinase essential for the initiation of DNA replication
Reagents tropicalis laevis.L laevis.S
CRISPRscan Tracks dbf4b
Morpholinos dbf4b MO1 dbf4b MO1 dbf4b MO1
Clones Horizon Source BioScience Horizon Source BioScience

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info   [+] Expand list
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