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Summary Expression Gene Literature (2) GO Terms (18) Nucleotides (124) Proteins (32) Interactants (23) Wiki
XB-GENEPAGE-5845784
Gene Symbol:
sprtn

Gene Name:
SprT-like N-terminal domain

Synonyms:
( Add synonyms , Nomenclature history )

Gene Function:
DNA binding

Protein Function :
Regulator of UV-induced DNA damage response: acts as a 'reader' of ubiquitinated pcna.



Interactants:
Loading ...

Diseases: 


Disease Ontology:
Ruijs-Aalfs syndrome

OMIM:
RUIJS-AALFS SYNDROME; RJALS

External Links:
 
Xenbase Gene ID XB-GENE-5845785 XB-GENE-17342065 XB-GENE-5845827
Gene Symbol sprtn sprtn.L sprtn.S
Chromosome Chr05 chr5S
Molecules tropicalis laevis.L laevis.S
Genomic Sequence Version 9.1 Version 9.2
CDS Gene model Gene model
Entrez Gene 100127870
100036995
mRNA RefSeq NCBI Nucleotide
Protein RefSeq Swiss-Prot Swiss-Prot NCBI Protein
Genomic
tropicalis laevis.L laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics tropicalis laevis.L laevis.S
Embryonic Protein Expression Stage profile:
Data Mining tropicalis laevis.L laevis.S
XenMine sprtn sprtn.L sprtn.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards SPRTN OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Sprtn MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Sprtn Ensembl
zebrafish
sprtn Ensembl
chicken
GEISHA SPRTN Ensembl
fruit fly
worm
Publications
First Mechanism and Regulation of DNA-Protein Crosslink Repair by the DNA-Dependent Metalloprotease SPRTN., Mol Cell 2016                  
Most Recent Replication-Coupled DNA-Protein Crosslink Repair by SPRTN and the Proteasome in Xenopus Egg Extracts., Mol Cell 2019                  
All View All Papers
Functional Ontologies tropicalis laevis.L laevis.S
GO 18 terms 0 term 2 terms
PANTHER sprtn
KEGG Pathways K24051 K24051
KOG [S] Uncharacterized conserved protein (alt_id KOG:3931)
Reagents tropicalis laevis.L laevis.S
CRISPRscan Tracks sprtn
Clones Horizon Source BioScience Horizon Source BioScience

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