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Summary Expression Gene Literature (39) GO Terms (21) Nucleotides (277) Proteins (53) Interactants (314) Wiki
XB-GENEPAGE-5850942
Gene Symbol:
birc5

Gene Name:
baculoviral IAP repeat-containing 5

Synonyms:
Survivin , xSurvivin1 , svv1 , Su2 , BIR1 , XBIR1 , api4 , epr-1 , xsurv , birc5.1-a , birc5.1-b , loc398389 ( Add synonyms , Nomenclature history )

Gene Function:
apoptosis inhibitor

Protein Function :
Component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignme...[+]



Interactants:
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Diseases: 


External Links:
 
Xenbase Gene ID XB-GENE-5850943 XB-GENE-5851077 XB-GENE-6254428
Gene Symbol birc5 birc5.L birc5.S
Chromosome Chr02 chr2L chr2S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 9.1 Version 9.2 Version 9.2
CDS Gene model Gene model Gene model
Entrez Gene 733532
398418
394382
mRNA RefSeq RefSeq RefSeq
Protein RefSeq Swiss-Prot  More.. RefSeq Swiss-Prot  More.. RefSeq Swiss-Prot  More..
Genomic
X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics X. tropicalis X. laevis.L X. laevis.S
Embryonic Protein Expression Stage profile: Stage profile:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine birc5 birc5.L birc5.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC AGR, OMIM:Gene, GeneCards BIRC5 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Birc5 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Birc5 Ensembl
zebrafish
ZFIN, AGR ZFIN, AGR birc5b birc5a ZFIN Ensembl
chicken
GEISHA BIRC5 Ensembl
fruit fly
worm
Publications
First Cloning and functional expression of the cDNA encoding an inwardly-rectifying potassium channel expressed in pancreatic beta-cells and in the brain., FEBS Lett 1995  
Most Recent Borealin-nucleosome interaction secures chromosome association of the chromosomal passenger complex., J Cell Biol 2019  
All View All Papers 1 paper(s) referencing morpholinos
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 18 terms 15 terms 17 terms
PANTHER birc5
KEGG Pathways K08731 K08731 K08731
KOG [DR] Apoptosis inhibitor IAP1 and related BIdomain proteins
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks birc5
Antibodies birc5 Ab1 birc5 Ab1 birc5 Ab1
ORFs birc5.1.S ORF1 , birc5.1.S ORF2
Clones Horizon Source BioScience Horizon Source BioScience Horizon Source BioScience
Plasmids Addgene Addgene

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info   [+] Expand list
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