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Summary Expression Gene Literature (40) GO Terms (5) Nucleotides (135) Proteins (24) Interactants (816) Wiki
XB-GENEPAGE- 5879292

Gene Symbol: dlx3

Gene Name: distal-less homeobox 3

Synonyms: xdlx3 , ai4 , tdo , Xdll-2 , dlx3-b , dlx3-a
Add Xenopus synonyms , Nomenclature history

Gene Function: homeodomain and LIM zinc binding domain transcription factor

Protein Function:
May have a regulatory function in the initial formation of the epidermis.


Interactants: Loading ...

OMIM Disease Associations: AMELOGENESIS IMPERFECTA, TYPE IV; AI4 [+]
 
Xenbase Gene ID XB-GENE-5879293 XB-GENE-5879348 XB-GENE-6254455
Gene Symbol dlx3 dlx3.L dlx3.S
Chromosome Chr10 chr9_10L chr9_10S
Molecules tropicalis laevis.L laevis.S
Gene Genomic sequence Genomic sequence Genomic sequence
CDS Gene model
Entrez Gene
Entrez Gene
Entrez Gene
mRNA Refseq Refseq NCBI Nucleotide
Protein Refseq TrEMBL TrEMBL Refseq Swiss-Prot NCBI Protein TrEMBL
Genomic tropicalis laevis.L laevis.S
Genome Browser
Links
Genomic Synteny Genomicus
Expression tropicalis laevis.L laevis.S
Ensembl Ensembl
UniGene Str.1302 Xl.59850 [+] Xl.838
RNA-Seq profile Stage profile: Stage profile:       Tissue heatmap:
Experimental regulation Regulation heatmap:
Images 63 expression image(s) for tropicalis and laevis
Data Mining tropicalis laevis.L laevis.S
XenMine dlx3 dlx3.L dlx3.S
Phenotype tropicalis laevis.L laevis.S
Smith Morpholino Screen    
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM:Gene, HGNC, GeneCards DLX3 OMIM, MalaCards, KEGG Disease, DECIPHER Ensembl, Protein Atlas, Allen Brain Atlas
mouse
MGI, AGR Dlx3 MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
zebrafish
ZFIN, AGR dlx3b ZFIN Ensembl
chicken
GEISHA DLX3 Ensembl
fruit fly
worm
WORMBASE
Publications
First: Xenopus Distal-less related homeobox genes are expressed in the developing forebrain and are induced by planar signals. [Development 1993]
Most recent: Identification of new regulators of embryonic patterning and morphogenesis in Xenopus gastrulae by RNA sequencing. [Dev Biol 2017]
View All Papers 13 paper(s) referencing morpholinos
Functional Ontologies tropicalis laevis.L laevis.S
GO 4 terms 4 terms 3 terms
PANTHER dlx3
KEGG Pathways K09315 K09315 K09315
KOG [K] Transcription factor DLX and related proteins with LIM Zn-binding and HOX domains
Reagents tropicalis laevis.L laevis.S
CRISPR / TALEN CRISPR tools CRISPR tools CRISPR tools
Clones EXRC - 2 clone(s)    
GE Dharmacon GE Dharmacon GE Dharmacon
Source BioScience Source BioScience Source BioScience
Morpholino dlx3 MO1 , dlx3 MO2 dlx3 MO1 , dlx3 MO2 dlx3 MO1 , dlx3 MO2
ORF dlx3 ORF2 , dlx3 ORF1 dlx3 ORF1
Affymetrix 1.0 Str.1302.1.S1_a_at Xl.838.1.S1_at [+]
Affymetrix 2.0 Xl2.838.1.S1_at [+] Xl2.838.1.S1_at

Symbol legend[+]
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Major funding for Xenbase is provided by the National Institute of Child Health and Human Development, grant P41 HD064556