[provisional- machine annotated only] Gene Symbol: ercc1 [Predicted: Source is Human Entrez Gene] Gene Name: excision repair cross-complementing rodent repair deficiency, complementation group 1 (includes overlapping antisense sequence) [Predicted: Source is Human Entrez Gene] Add Xenopus synonyms Gene Function: structure-specific endonuclease component Interactants: gtf2h4(1) , rpa1(1) , xpa(1) , View All

Molecules		tropicalis	laevis
Gene		JGI XT Genome 7.1 JGI XT Genome 4.1 Ensembl 4.1	JGI XL Genome 6.0
		Entrez Gene	Entrez Gene
mRNA		Refseq >NM_001113921|Xenopus (Silurana) tropicalis excision repair cross-complementing rodent repair deficiency, complementation group 1 (includes overlapping antisense sequence) (ercc1), mRNA CAGGGAGAGACGGATAAATGGAGCATCATTAACTTTCAGCTGACCAGTATGGAAAAGAAAAATTATAACTCGAGAGAAGGGGGACCCAAAATATTTCTATCCAAGGAGCCAGTTTCTCATCCGGAGGAGACGAAGAGTACTGTACCAAAACACCAAGTTAGCAGTGTGGGTGTAAGAGAAAATGAAGTTTGCATTATGGAGCAAGCAGCGAATCAAACTACAAAGTCTGTAGGAGTGAGAAGCAGTATTATTGTCAGCACCCGACAGCGAGGAAACTCACTACTTAAATATTTGCGAAATGTGCCATGGGAGTTCGGAAACATTATTCCCGACTATGTACTTGGGGAAACCTGCTGTGCTCTCTTTCTGAGTCTGCGTTACCATAATCTGAATCCAGAGTACATACATTTGCGTCTGAGGTCCCTTGGTCAATCCTTTGCACTACGTGTGCTTCTTGTACAAGTGGATGTGAAAGACCCTCATTTTTCTCTTAAAGAGTTGGCAAAGATCTGTATCCTTTCTGATTGCACACTAATACTAAGCTGGAGTCCTGAGGAGGCTGCCCGGTACCTTGAGACATACAAATGTTATGAGCAGAAGCCTGCAGATGTGCTGAAAGAAAGAACTGAGAAGGACCTTATGTCCAGAATGGCAGAGTGTCTCACAACTGTTAAGTATGTAAACAAGACAGACAGCTGTACTTTATTCACCACATTTGGGACTTTGTTTGACCTTGCAAATGCATCACGTGAAGATCTTTCTTTATGCCCTGGCCTTGGACCTCAGAAAGCTAAAAGACTATATGACACATTTCATGAACCATTCCTAAAAACAAGCACAATGACATTTCAGTGAAAGTCTTTGGAACTAACGGAACAGCAATGATTCCACGTGACTGGGACAACCTAAAGCTATGTAAAAGGATTTTTTTTAGGGAACTAATTTCTGTTACATAATTTCTGTTAAGTGTGAAAAATTAAAATGTTGTGTGGCTATTTCCAATTTGCAACTTTTAATTTGACATTTATTTGTTTGCACATTTTGTATGCCATAGGGCTGGTTTACCTATCTAACCTGTAGTGCAAAAGTGCATTTATTAAAACTCTATTTTTGCGTAAAAAAAAAAAAAAAA	Refseq >NM_001087029|Xenopus laevis excision repair cross-complementing rodent repair deficiency, complementation group 1 (includes overlapping antisense sequence) (ercc1), mRNA CTGGATTGCGATATGTGCTTGTAATTTATGGATCTGTTGTCCTGGCAGCAGCAAACGTTTAGCTGACCAGTATGGAAGAAAAAAATTATAATTCAAGAGAAGGAGGACTCCAAAGATTTCTTATTCCATCACCATCATCCATCACCCAGGAGGCAGTTTCTCAACCGAAATGCTCGTTCTTTCAGGCCTCAGAAAAAGTAGAAACAGTCCCAAAAGCTGGGAGTTATGCAGATTACATTTTTCAGAAGGAGGCATGGGATCCTGTACAAAAAGGCCAATTTAGCAATATGGCTGCAAGTGAAAATGCAGTTTCTATTGTGAAGCAAACAACAAATCAAACCACAAAGTCCGCAGGAGCGGGAAGCTGCATTCTTGTCAGCACCCGACAGAGAGGAAACTCGCTACTTAAATATTTGCGAAATGTACCATGGGAGTTCAGTGACATTGTTCCAGACTATATACTTGGGGAAACCTGCTGTTCTCTCTTTCTGAGTCTACGATACCATAATCTGAATCCAGAGTACATACACTCTCGTCTGAGGTCCCTTGGTCAATCCTTTGCACTTCGTGTGCTTCTTGTACAAGTGGACGTGAAAGACCCTCATTTTTCCCTTAAAGAGTTGGCAAAGATCTGTATCCTGTCTGATTGCACACTAATACTGAGCTGGAGTCCTGAGGAGGCTGCTCGGTACCTTGAGACATATAAATGTTATGAACAGAAACCTGCAGATGCTCTGAAAGAAAGAACTGAGAAGGACTTCATGTCTACGATGACAGAGTGTCTCACAACTGTTAAGTATGTAAACAAGACAGACAGCTGCACTCTATTTACCACGTTTGGGACTCTGTTTGACCTTGCAAATGCATCACGTGAAGATCTTTCTTTATGCCCTGGCCTCGGACCCCAGAAATTGCTAGGAGAGTTGAGAATCGGAGACTGAACATCGATCTCAAGCTATCTCCTGAATTGGCATTACTTGACTTTCAGACGACCTCCTCTCCCAAGATGAAACTTTGGAATAAGTATAAACATTTTATTTTCATGGTCCTTGCAGCTACACGTAAATTAATTTTGGATTCAAGAAAACTCCCCAGATTTAAAAGATGTTTTGTTTTATCTTAGGTCTCTTTGTTTGGATGCAGCAGTTTTAGATATGGTAGCTCTGGCTTTATGGACACATTTTAAAAATGTTGGTCCCTATACTTTAACTTTCTGGGTTCTGAGAATAAAGCCATAATTGAAAAATGTATGTTCAGTTCTGACAGAGATTCTATTTTACATACTCACAGGAGTTTTAATATTTGATGGAAGATGTGCTTTTTTCTGTATAAGATGTAGTTAATTGTTTTGTTGGACTGACGGACAGGACTTTTCTTTTTACTGTTATGTTTGTTTTTATTTTTTTTAGTTTTGTTTTCTATGTTATTTTATGGTCTAATCTAAGGCATCATTCAATGTTTATTTTCTTTGGATTGATAGGTAATAATCCTGTACTGTTACATTAACTGATGGGCTTATGTCAGCCAATCCTTTGTTATGTTGTTTATTTCTCATGCTGTTTATTTGAAAATGCTAATAAACACAATTGAAAAGAAAAAAAAAAAAAAAA
Protein		Refseq >NP_001107393|excision repair cross-complementing rodent repair deficiency, complementation group 1 (includes overlapping antisense sequence) [Xenopus (Silurana) tropicalis] MEKKNYNSREGGPKIFLSKEPVSHPEETKSTVPKHQVSSVGVRENEVCIMEQAANQTTKSVGVRSSIIVSTRQRGNSLLKYLRNVPWEFGNIIPDYVLGETCCALFLSLRYHNLNPEYIHLRLRSLGQSFALRVLLVQVDVKDPHFSLKELAKICILSDCTLILSWSPEEAARYLETYKCYEQKPADVLKERTEKDLMSRMAECLTTVKYVNKTDSCTLFTTFGTLFDLANASREDLSLCPGLGPQKAKRLYDTFHEPFLKTSTMTFQ	Refseq >NP_001080498|excision repair cross-complementing 1 [Xenopus laevis] MEEKNYNSREGGLQRFLIPSPSSITQEAVSQPKCSFFQASEKVETVPKAGSYADYIFQKEAWDPVQKGQFSNMAASENAVSIVKQTTNQTTKSAGAGSCILVSTRQRGNSLLKYLRNVPWEFSDIVPDYILGETCCSLFLSLRYHNLNPEYIHSRLRSLGQSFALRVLLVQVDVKDPHFSLKELAKICILSDCTLILSWSPEEAARYLETYKCYEQKPADALKERTEKDFMSTMTECLTTVKYVNKTDSCTLFTTFGTLFDLANASREDLSLCPGLGPQKLLGELRIGD

Genomic		tropicalis
Genome Browser		Xenbase	Xenbase JGI Ensembl UCSC		Xenbase
Synteny		Metazome

Expression		tropicalis	laevis
UniGene		Str.30680 [+] Str.74309	Xl.21900
Unigene EST Profile		EST Profile	EST Profile
GEO data			GEO
Images		0 expression image(s) for tropicalis and laevis

Orthology		MOD	Entrez Gene	Genetic Phenotypes	Morphants
human		OMIM:Gene, HGNC	ERCC1	OMIM:610758
mouse		MGI	Ercc1	All(6) Targeted, knock Out(2) Targeted, other(4)
zebrafish		ZFIN	ercc1

Publications
First:		Extended X-ray absorption fine structure evidence for a single metal binding domain in Xenopus laevis nucleotide excision repair protein XPA. [Biochem Biophys Res Commun 1999]
Most recent:
		View All Papers

Functional Ontologies
GO: Molecular:		damaged DNA binding endonuclease activity
Biological:		DNA repair
Cellular Component:		nucleus
EC:
KOG:		[L] Structure-specific endonuclease ERCC1-XPF, ERCC1 component

Reagents		tropicalis	laevis
Clones		open biosystems	open biosystems
		geneservice/RZPD imagenes	geneservice/RZPD imagenes
Affymetrix 1.0		Str.30680.1.A1_at [+] Str.49148.1.S1_at	Xl.21900.1.S1_at
Affymetrix 2.0			Xl2.21900.1.S1_at

Symbol legend[+]

- Blast this sequence
   - Literature Or Expression Images