Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Summary Expression Gene Literature (3) GO Terms (17) Nucleotides (150) Proteins (22) Interactants (131) Wiki
XB-GENEPAGE- 5900919

Gene Symbol: kdm7a

Gene Name: lysine (K)-specific demethylase 7A

Synonyms: kdm7 , Jhdm1d
Add Xenopus synonyms , Nomenclature history


Gene Function: transcriptional regulator

Protein Function :
Histone demethylase required for brain development. Specifically demethylates dimethylated 'Lys-9' and 'Lys-27' (H3K9me2 and H3K27me2, respectively) of histone H3 and monomethylated histone H4 'Lys-20'...[+]


Interactants: Loading ...

Disease Ontology:
  

OMIM Diseases:
  
 

Xenbase Gene ID XB-GENE-5900920 XB-GENE-17343126 XB-GENE-5900967
Gene Symbol kdm7a kdm7a.L kdm7a.S
Chromosome Chr03 chr3L chr3S
Molecules tropicalis laevis.L laevis.S
Gene Genomic sequence Genomic sequence Genomic sequence
CDS Gene model
Entrez Gene
Entrez Gene
mRNA Refseq Refseq
Protein Refseq Swiss-Prot TrEMBL TrEMBL Refseq TrEMBL
Genomic tropicalis laevis.L laevis.S
Genome Browser
Links
Genomic Synteny Genomicus PANTHER
Expression tropicalis laevis.L laevis.S
Ensembl Ensembl
UniGene Str.52832 [+] Xl.13425 [+]
RNA-Seq profile Stage profile: Stage profile:       Tissue heatmap:
Experimental regulation Regulation heatmap:
Images 0 expression image(s) for tropicalis and laevis
Data Mining tropicalis laevis.L laevis.S
XenMine kdm7a kdm7a.L kdm7a.S
Phenotype tropicalis laevis.L laevis.S
Smith Morpholino Screen    
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
KDM7A OMIM, MalaCards, KEGG Disease, DECIPHER Ensembl, Protein Atlas, Allen Brain Atlas
mouse
MGI, AGR Kdm7a MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
zebrafish
ZFIN, AGR ZFIN, AGR kdm7aa kdm7ab ZFIN Ensembl
chicken
GEISHA KDM7A Ensembl
fruit fly
worm
WORMBASE
Publications
First: A genetic map of Xenopus tropicalis. [Dev Biol 2011]
Most recent: KDM3A-mediated demethylation of histone H3 lysine 9 facilitates the chromatin binding of Neurog2 during neurogenesis. [Development 2017]
View All Papers 1 paper(s) referencing morpholinos
Functional Ontologies tropicalis laevis.L laevis.S
GO 17 terms 0 term 3 terms
PANTHER kdm7a
KEGG Pathways K11445 K11445
KOG [B] F-box protein JEMMA and related proteins with JmjC, PHD, F-box and LRR domains
Reagents tropicalis laevis.L laevis.S
CRISPR / TALEN CRISPR tools CRISPR tools CRISPR tools
Clones
GE Dharmacon GE Dharmacon GE Dharmacon
Source BioScience Source BioScience
ORF kdm7a.S ORF1
Affymetrix 1.0 StrJgi.5962.1.S1_at [+] Xl.13425.1.A1_at [+]
Affymetrix 2.0 Xl2.13425.1.S1_at [+]

Symbol legend[+]
Xenbase: The Xenopus laevis and X. tropicalis resource.
Version: 4.9.2
Major funding for Xenbase is provided by the National Institute of Child Health and Human Development, grant P41 HD064556