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Summary Expression Gene Literature (3) GO Terms (8) Nucleotides (100) Proteins (22) Interactants (15) Wiki
XB-GENEPAGE- 5910468

Gene Symbol: c21orf59

Gene Name: chromosome 21 open reading frame 59

Synonyms: kur , kurly
Add Xenopus synonyms , Nomenclature history


Gene Function:

Protein Function:
Plays a role in motile cilium function, possibly by acting on outer dynein arm assembly (PubMed:26904945). Seems to be important for initiation rather than maintenance of cilium motility. Required for ...[+]


Interactants: Loading ...

OMIM Disease Associations: CILIARY DYSKINESIA, PRIMARY, 26; CILD26
 
Xenbase Gene ID XB-GENE-5910469 XB-GENE-5910499 XB-GENE-17342827
Gene Symbol c21orf59 c21orf59.L c21orf59.S
Chromosome scaffold_77 chr2L chr2S
Molecules tropicalis laevis.L laevis.S
Gene GBrowse 8.0 JBrowse 8.0 GBrowse 7.1 JBrowse 7.1 GBrowse 4.1 JGI Genome 4.1 Ensembl 4.1 GBrowse 9.1 JBrowse 9.1 GBrowse 7.2 JBrowse 7.2 GBrowse 6.0 GBrowse 9.1 JBrowse 9.1
Entrez Gene
Entrez Gene
mRNA NCBI Nucleotide Refseq
Protein NCBI Protein TrEMBL Refseq Swiss-Prot
Genomic tropicalis laevis.L laevis.S
Genome Browser
Links
Genomic Synteny Genomicus   Metazome
Expression tropicalis laevis.L laevis.S
Ensembl Ensembl
UniGene Str.53349 Xl.4468
RNA-Seq profile Stage profile: Stage profile:       Tissue heatmap:
Experimental regulation Regulation heatmap:
Images 0 expression image(s) for tropicalis and laevis
Data Mining tropicalis laevis.L laevis.S
XenMine c21orf59 c21orf59.L c21orf59.S
Phenotype tropicalis laevis.L laevis.S
Smith Morpholino Screen    
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
C21orf59 OMIM, MalaCards, KEGG Disease, DECIPHER Ensembl, Protein Atlas, Allen Brain Atlas
mouse
MGI, IMPC Eurexpress, MGI, Allen Brain Atlas
zebrafish
ZFIN c10h21orf59 ZFIN Ensembl
chicken
fruit fly
worm
WORMBASE
Publications
First: Zebrafish mutations affecting cilia motility share similar cystic phenotypes and suggest a mechanism of cyst formation that differs from pkd2 morphants. [Dev Biol 2008]
Most recent: c21orf59/kurly Controls Both Cilia Motility and Polarization. [Cell Rep 2016]
View All Papers 1 paper(s) referencing morpholinos
Functional Ontologies tropicalis laevis.L laevis.S
GO 5 terms 3 terms 0 term
EC
PANTHER c21orf59
KEGG Pathways
KOG
Reagents tropicalis laevis.L laevis.S
CRISPR / TALEN CRISPR tools CRISPR tools CRISPR tools
Clones
GE Dharmacon GE Dharmacon GE Dharmacon
Source BioScience Source BioScience
Morpholino c21orf59 MO1 , c21orf59 MO2 , c21orf59 MO3 c21orf59 MO1 , c21orf59 MO2 , c21orf59 MO3 c21orf59 MO1 , c21orf59 MO2 , c21orf59 MO3
ORF c21orf59 ORF1
Affymetrix 1.0 Str.11895.1.S1_at Xl.4468.1.S1_at
Affymetrix 2.0 Xl2.4468.1.S1_at

Symbol legend[+]

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