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Summary Expression Gene Literature (5) GO Terms (14) Nucleotides (123) Proteins (32) Interactants (47) Wiki
Gene Symbol:

Gene Name:
cilia and flagella associated protein 298

kur , kurly , c21orf59 ( Add synonyms , Nomenclature history )

Gene Function:
This gene encodes a protein that plays a critical role in dynein arm assembly and motile cilia function.

Protein Function :
Plays a role in motile cilium function, possibly by acting on outer dynein arm assembly (PubMed:26904945). Seems to be important for initiation rather than maintenance of cilium motility. Required for ...[+]

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Disease Ontology:
Kartagener syndrome [+]


External Links:
Xenbase Gene ID XB-GENE-5910469 XB-GENE-5910499 XB-GENE-17342827
Gene Symbol cfap298 cfap298.L cfap298.S
Chromosome Chr2 chr2L chr2S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.1 Version 9.1
CDS Gene model Gene model Gene model
Entrez Gene 100380199
mRNA NCBI Nucleotide NCBI Nucleotide NCBI Nucleotide
Protein NCBI Protein RefSeq Swiss-Prot  More..
X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics X. tropicalis X. laevis.L X. laevis.S
Embryonic Protein Expression Stage profile: Stage profile:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine cfap298 cfap298.L cfap298.S
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
HGNC, AGR, Monarch, OMIM, GeneCards CFAP298 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
MGI, AGR Cfap298 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
RGD, AGR Cfap298 Ensembl
ZFIN, AGR cfap298 ZFIN Ensembl
fruit fly
First Zebrafish mutations affecting cilia motility share similar cystic phenotypes and suggest a mechanism of cyst formation that differs from pkd2 morphants., Dev Biol 2008  
Most Recent In Xenopus ependymal cilia drive embryonic CSF circulation and brain development independently of cardiac pulsatile forces., Fluids Barriers CNS 2020                    
All View All Papers 1 paper(s) referencing morpholinos 1 paper(s) referencing OMIMs 1 paper(s) referencing Disease Ontology
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 11 terms 4 terms 0 term
PANTHER cfap298
KEGG Pathways K24229
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks cfap298
Morpholinos cfap298 MO4 cfap298 MO1 , cfap298 MO3 , cfap298 MO2 , cfap298 MO4 cfap298 MO2
ORFs cfap298.L ORF1
Clones Horizon Source BioScience Horizon Source BioScience Horizon
Plasmids Addgene Addgene

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