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Summary Expression Gene Literature (2) GO Terms (57) Nucleotides (137) Proteins (44) Interactants (121) Wiki
XB-GENEPAGE-5914265
Gene Symbol:
rnf8

Gene Name:
ring finger protein 8, E3 ubiquitin protein ligase

Synonyms:
rnf8-b , rnf8-a ( Add synonyms , Nomenclature history )

Gene Function:
FHA domain

Protein Function :
E3 ubiquitin-protein ligase that plays a key role in DNA damage signaling via 2 distinct roles: by mediating the 'Lys-63'-linked ubiquitination of histones H2A and H2AX and promoting the recruitment of...[+]



Interactants:
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Diseases: 


External Links:
 
Xenbase Gene ID XB-GENE-5914266 XB-GENE-5914276 XB-GENE-6254223
Gene Symbol rnf8 rnf8.L rnf8.S
Chromosome Chr5 chr5L chr5S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.2 Version 9.2
CDS Gene model Gene model Gene model
Entrez Gene 100216121
431911
380076
mRNA NCBI Nucleotide NCBI Nucleotide NCBI Nucleotide
Protein NCBI Protein RefSeq  More.. RefSeq Swiss-Prot  More.. RefSeq Swiss-Prot  More..
Genomic
X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine rnf8 rnf8.L rnf8.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC, AGR, Monarch, OMIM, GeneCards RNF8 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Rnf8 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Rnf8 Ensembl
zebrafish
ZFIN, AGR rnf8 ZFIN Ensembl
chicken
GEISHA RNF8 Ensembl
fruit fly
Publications
First Comparative expression analysis of cysteine-rich intestinal protein family members crip1, 2 and 3 during Xenopus laevis embryogenesis., Int J Dev Biol 2014                                                
Most Recent A Tissue-Mapped Axolotl De Novo Transcriptome Enables Identification of Limb Regeneration Factors., Cell Rep 2017                            
All View All Papers
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 48 terms 25 terms 26 terms
PANTHER rnf8
KEGG Pathways K10667 K10667 K10667
KOG [T] FOG: FHA domain
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks rnf8
ORFs rnf8.L ORF1 rnf8.S ORF1
Clones Horizon Source BioScience Horizon Source BioScience Horizon Source BioScience
Plasmids Addgene Addgene

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