Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Summary Expression Gene Literature (164) GO Terms (24) Nucleotides (91) Proteins (23) Interactants (305) Wiki
XB-GENEPAGE-5921461

Gene Symbol: kcnq1

Gene Name: potassium channel, voltage gated KQT-like subfamily Q, member 1

Synonyms: kv7.1 ( Add Xenopus synonyms , Nomenclature history )

Gene Function: voltage-gated potassium channel activity

Protein Function :
Potassium channel that plays an important role in a number of tissues, including heart, inner ear, stomach and colon. Associates with KCNE beta subunits that modulates current kinetics. Induces a volta...[+]

Interactants: Loading ...
Disease Ontology: familial atrial fibrillation [+]

OMIM Diseases: ATRIAL FIBRILLATION, FAMILIAL, 3; ATFB3 [+]

1/4
 
Xenbase Gene ID XB-GENE-5921462 XB-GENE-5921471 XB-GENE-17332712
Gene Symbol kcnq1 kcnq1.L kcnq1.S
Chromosome Chr04 chr4L chr4S
Molecules tropicalis laevis.L laevis.S
Gene Genomic sequence Genomic sequence Genomic sequence
CDS Gene model
Entrez Gene
Entrez Gene
mRNA NCBI Nucleotide Refseq
Protein NCBI Protein TrEMBL Refseq Swiss-Prot TrEMBL Swiss-Prot
Genomic tropicalis laevis.L laevis.S
Genome Browser
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics tropicalis laevis.L laevis.S
Embryonic Protein Expression Stage profile: Stage profile:
Data Mining tropicalis laevis.L laevis.S
XenMine kcnq1 kcnq1.L kcnq1.S
Phenotype tropicalis laevis.L laevis.S
Smith Morpholino Screen    
Orthology
MOD Entrez Gene Genetic Phenotypes Gene Expression
human
OMIM:Gene, HGNC, GeneCards KCNQ1 OMIM, MalaCards, KEGG Disease, DECIPHER Ensembl, Protein Atlas, Allen Brain Atlas
mouse
MGI, AGR Kcnq1 MGI, IMPC Ensembl, Eurexpress, MGI, Allen Brain Atlas
zebrafish
ZFIN, AGR kcnq1.1 ZFIN Ensembl
chicken
GEISHA KCNQ1 Ensembl
fruit fly
worm
WORMBASE
Publications
First I(sK) Channel in Strial Marginal Cells. Voltage-Dependence, Ion-Selectivity, Inhibition by 293B and Sensitivity to Clofilium., Audit Neurosci 1997  
Most Recent Probing the Dynamics and Structural Topology of the Reconstituted Human KCNQ1 Voltage Sensor Domain (Q1-VSD) in Lipid Bilayers Using Electron Paramagnetic Resonance Spectroscopy., Biochemistry 2019  
All View All Papers 2 paper(s) referencing morpholinos 164 paper(s) referencing OMIMs 164 paper(s) referencing Disease Ontology
Functional Ontologies tropicalis laevis.L laevis.S
GO 10 terms 19 terms 0 term
PANTHER kcnq1
KEGG Pathways K04926
KOG [P] Voltage-gated K+ channel KCNQ
Reagents tropicalis laevis.L laevis.S
CRISPR / TALEN CRISPR tools CRISPR tools CRISPR tools
Clones
GE Dharmacon GE Dharmacon GE Dharmacon
Antibody Kcnq1 Ab1 , Kcnq1 Ab2 Kcnq1 Ab1 , Kcnq1 Ab2
Affymetrix 1.0 StrJgi.2763.1.S1_s_at [+] Xl.21509.1.S1_at [+]
Affymetrix 2.0 Xl2.42496.1.A1_at [+]

Symbol legend: - Blast this sequence    - View this sequence       - Literature or expression images  
Xenbase: The Xenopus laevis and X. tropicalis resource.
Version: 4.11.0


Major funding for Xenbase is provided by grant P41 HD064556