Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Summary Expression Gene Literature (18) GO Terms (20) Nucleotides (145) Proteins (52) Interactants (73) Wiki
XB-GENEPAGE-5953133
Gene Symbol:
rbbp8

Gene Name:
retinoblastoma binding protein 8

Synonyms:
ctip ( Add synonyms , Nomenclature history )

Gene Function:
Predicted RNA-binding protein, contains SWAP and G-patch domains

Protein Function :
Endonuclease that cooperates with the MRE11-RAD50-NBN (MRN) complex in DNA-end resection, the first step of double-strand break (DSB) repair through the homologous recombination (HR) pathway. Functions...[+]



Interactants:
Loading ...

Diseases: 


Disease Ontology:
Seckel syndrome [+]

OMIM:
JAWAD SYNDROME; JWDS [+]

External Links:
 
Xenbase Gene ID XB-GENE-5953134 XB-GENE-5953161 XB-GENE-17334925
Gene Symbol rbbp8 rbbp8.L rbbp8.S
Chromosome Chr6 chr6L chr6S
Molecules X. tropicalis X. laevis.L X. laevis.S
Genomic Sequence Version 10.0 Version 9.1 Version 9.1
CDS Gene model Gene model Gene model
Entrez Gene 100380142
444252
108695266
mRNA NCBI Nucleotide NCBI Nucleotide NCBI Nucleotide
Protein NCBI Protein NCBI Protein  More.. RefSeq Swiss-Prot  More.. NCBI Protein NCBI Protein  More..
Genomic
X. tropicalis X. laevis.L X. laevis.S
Genome Browser
(Click image to open in Genome Browser)
Genomic Synteny Genomicus PANTHER
Expression                  Development Stages    Embryonic TissuesAdult Tissues
Summary for
More Information
Xenbase Expression Details In situ images Single cell data at SPRING Ensembl In situ: Single cell: RNA-Seq:
Proteomics X. tropicalis X. laevis.L X. laevis.S
Embryonic Protein Expression Stage profile:
Data Mining X. tropicalis X. laevis.L X. laevis.S
XenMine rbbp8 rbbp8.L rbbp8.S
Orthology
Knowledgebases Entrez Gene Genetic Phenotypes Gene Expression
human
HGNC, AGR, Monarch, OMIM, GeneCards RBBP8 OMIM Ensembl, Allen Brain Atlas, Protein Atlas
mouse
MGI, AGR Rbbp8 MGI, IMPC Ensembl, Allen Brain Atlas, Eurexpress, MGI
rat
RGD, AGR Rbbp8 Ensembl
zebrafish
ZFIN, AGR rbbp8 ZFIN Ensembl
chicken
GEISHA RBBP8 Ensembl
fruit fly
Publications
First RBP-Jkappa/SHARP recruits CtIP/CtBP corepressors to silence Notch target genes., Mol Cell Biol 2005  
Most Recent Dna2 initiates resection at clean DNA double-strand breaks., Nucleic Acids Res 2017              
All View All Papers 1 paper(s) referencing OMIMs 1 paper(s) referencing Disease Ontology
Functional Ontologies X. tropicalis X. laevis.L X. laevis.S
GO 19 terms 7 terms 7 terms
PANTHER rbbp8
KEGG Pathways K20773 K20773
KOG [R] Predicted RNA-binding protein, contains SWAP and G-patch domains
Reagents X. tropicalis X. laevis.L X. laevis.S
CRISPRscan Tracks rbbp8
ORFs rbbp8.L ORF1
Clones Horizon Source BioScience Horizon Source BioScience Horizon
Plasmids Addgene Addgene

Symbol legend: Blast sequence    View sequence    Literature or expression images   Hover cursor for info